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Continuing Orthohantavirus Circulation in Deer Mice in Western Montana [PDF]

open access: yesViruses, 2021
Hantavirus pulmonary syndrome (HPS) is an often-fatal disease caused by New World hantaviruses, such as Sin Nombre orthohantavirus (SNV). In the US, >800 cases of HPS have been confirmed since it was first discovered in 1993, of which 43 were reported ...
Brandi N. Williamson   +9 more
doaj   +2 more sources

Maporal Hantavirus Causes Mild Pathology in Deer Mice (Peromyscus maniculatus)

open access: yesViruses, 2016
Rodent-borne hantaviruses can cause two human diseases with many pathological similarities: hantavirus cardiopulmonary syndrome (HCPS) in the western hemisphere and hemorrhagic fever with renal syndrome in the eastern hemisphere.
Amanda McGuire   +7 more
doaj   +3 more sources

Linking Dysregulated AMPK Signaling and ER Stress in Ethanol-Induced Liver Injury in Hepatic Alcohol Dehydrogenase Deficient Deer Mice

open access: yesBiomolecules, 2019
Ethanol (EtOH) metabolism itself can be a predisposing factor for initiation of alcoholic liver disease (ALD). Therefore, a dose dependent study to evaluate liver injury was conducted in hepatic alcohol dehydrogenase (ADH) deficient (ADH−) and ADH normal
Mukund P. Srinivasan   +6 more
doaj   +3 more sources

SARS-CoV-2 infection and transmission in the North American deer mouse

open access: yesNature Communications, 2021
Deer mice are natural hosts for a number of human pathogens. Here, Griffin et al. report that intranasal exposure of the North American deer mouse to SARS-CoV-2 results in virus replication and shedding, despite causing only mild or asymptomatic illness.
Bryan D. Griffin   +27 more
doaj   +1 more source

Anthropogenic noise decreases activity and calling behavior in wild mice [PDF]

open access: yesPeerJ, 2023
Background Animals rely on sound to mediate a myriad of daily activities, and anthropogenic noise is a pollutant that alters the natural soundscape within which they are active.
Radmila Petric   +1 more
doaj   +2 more sources

Development and Characterization of a Sin Nombre Virus Transmission Model in Peromyscus maniculatus

open access: yesViruses, 2019
In North America, Sin Nombre virus (SNV) is the main cause of hantavirus cardiopulmonary syndrome (HCPS), a severe respiratory disease with a fatality rate of 35⁻40%. SNV is a zoonotic pathogen carried by deer mice (Peromyscus maniculatus), and few
Bryce M. Warner   +9 more
doaj   +1 more source

Natural History of Sin Nombre Virus in Western Colorado

open access: yesEmerging Infectious Diseases, 1999
A mark-recapture longitudinal study of immunoglobulin G (IgG) antibody to Sin Nombre virus (SNV) in rodent populations in western Colorado (1994—results summarized to October 1997) indicates the presence of SNV or a closely related hantavirus at two ...
Charles H. Calisher   +3 more
doaj   +1 more source

Profiling helper T cell subset gene expression in deer mice

open access: yesBMC Immunology, 2006
Background Deer mice (Peromyscus maniculatus) are the most common mammals in North America and are reservoirs for several zoonotic agents, including Sin Nombre virus (SNV), the principal etiologic agent of hantavirus cardiopulmonary syndrome (HCPS) in ...
Hjelle Brian   +6 more
doaj   +1 more source

Oral Vaccination With Recombinant Vesicular Stomatitis Virus Expressing Sin Nombre Virus Glycoprotein Prevents Sin Nombre Virus Transmission in Deer Mice

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Sin Nombre virus (SNV) is the major cause of hantavirus cardiopulmonary syndrome (HCPS) in North America, a severe respiratory disease with a high fatality rate. SNV is carried by Peromyscus maniculatus, or deer mice, and human infection occurs following
Bryce M. Warner   +12 more
doaj   +1 more source

In vitro maturation of cumulus-oocyte complexes for efficient isolation of oocytes from outbred deer mice. [PDF]

open access: yesPLoS ONE, 2013
BackgroundThe outbred (as with humans) deer mice have been a useful animal model of research on human behavior and biology including that of the reproductive system.
Jung Kyu Choi, Xiaoming He
doaj   +1 more source

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