Results 41 to 50 of about 25,067 (185)

Sin Nombre Virus Pathogenesis inPeromyscus maniculatus [PDF]

open access: yesJournal of Virology, 1999
ABSTRACT Sin Nombre virus (SNV), a member of the Hantavirus genus, causes acute viral pneumonia in humans and is thought to persistently infect mice. The deer mouse, Peromyscus maniculatus , has been identified as the primary reservoir host for SNV. To understand SNV infection of
Dale Netski   +2 more
semanticscholar   +3 more sources

Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies

open access: yeseLife, 2023
Hantaviruses are high-priority emerging pathogens carried by rodents and transmitted to humans by aerosolized excreta or, in rare cases, person-to-person contact.
Taylor B Engdahl   +21 more
doaj   +1 more source

Neutralizing Monoclonal Antibodies against the Gn and the Gc of the Andes Virus Glycoprotein Spike Complex Protect from Virus Challenge in a Preclinical Hamster Model

open access: yesmBio, 2020
Hantaviruses are the etiological agent of hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The latter is associated with case fatality rates ranging from 30% to 50%.
James Duehr   +10 more
doaj   +1 more source

Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection

open access: yesCell Reports, 2021
Summary: New World hantaviruses (NWHs) are endemic in North and South America and cause hantavirus cardiopulmonary syndrome (HCPS), with a case fatality rate of up to 40%. Knowledge of the natural humoral immune response to NWH infection is limited. Here,
Taylor B. Engdahl   +15 more
doaj   +1 more source

Complete genetic characterization and analysis of isolation of Sin Nombre virus [PDF]

open access: yesJournal of Virology, 1995
This study reports completion of the genetic characterization of the entire genome of Sin Nombre (SN) virus (NMH10) detected in autopsy tissues from a patient who died of hantavirus pulmonary syndrome (HPS). The large (L) genome segment was found to be 6,562 nucleotides in length and encoded a putative L polymerase that was 2,153 amino acids in length.
V E, Chizhikov   +5 more
openaire   +2 more sources

Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population [PDF]

open access: yes, 2012
Rodent gammaherpesviruses have become important models for understanding human herpesvirus diseases. In particular, interactions between murid herpesvirus 4 and Mus musculus (a non-natural host species) have been extensively studied under controlled ...
Pedersen, Amy B.   +2 more
core   +1 more source

Hantavirus and Arenavirus Antibodies in Persons with Occupational Rodent Exposure, North America

open access: yesEmerging Infectious Diseases, 2007
Rodents are the principal hosts of Sin Nombre virus, 4 other hantaviruses known to cause hantavirus pulmonary syndrome in North America, and the 3 North American arenaviruses.
Charles F. Fulhorst   +7 more
doaj   +1 more source

The Coiled-coil Domain Structure of the Sin Nombre Virus Nucleocapsid Protein [PDF]

open access: yesJournal of Molecular Biology, 2007
Hantaviruses can cause hemorrhagic fever with a renal syndrome and hantavirus pulmonary syndrome when transmitted to humans. The nucleocapsid protein of hantaviruses encapsidates viral genomic RNA and associates with transcription and replication complexes.
Sergei P, Boudko   +2 more
openaire   +2 more sources

Biodefense Implications of New-World Hantaviruses

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Hantaviruses, part of the Bunyaviridae family, are a genus of negative-sense, single-stranded RNA viruses that cause two major diseases: New-World Hantavirus Cardiopulmonary Syndrome and Old-World Hemorrhagic Fever with Renal Syndrome.
Michael Hilary D’Souza   +3 more
doaj   +1 more source

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