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América sin Nombre. N. 1 (dic. 1999) [PDF]
Neruda con la perspectiva de 25 ...
América sin Nombre
core +1 more source
ABSTRACT Introduction Hantavirus cardiopulmonary syndrome (HCPS) is a severe zoonotic disease caused by Orthohantavirus andesense (Andes virus, ANDV), with significant public health burden in Chile. Despite decades of surveillance, knowledge gaps remain regarding the ecological drivers of notification burden and the individual‐level determinants of in ...
Benjamín Diethelm‐Varela +7 more
wiley +1 more source
Hantaviruses, including the Sin Nombre virus (SNV) and Andes virus (ANDV), are associated with severe global health risks, causing high mortality rates in hantavirus pulmonary syndrome (HPS) patients.
Punya Shrivastava-Ranjan +10 more
doaj +1 more source
Neutralizing Antibodies in Survivors of Sin Nombre and Andes Hantavirus Infection
We evaluated titers of homotypic and heterotypic neutralizing antibodies (NAbs) to Andes and Sin Nombre hantaviruses in plasma samples from 20 patients from Chile and the United States. All but 1 patient had high titers of NAb. None of the plasma samples
Francisca Valdivieso +6 more
doaj +1 more source
SEASONAL VARIATION IN SIN NOMBRE VIRUS INFECTIONS IN DEER MICE: PRELIMINARY RESULTS [PDF]
The proportion of deer mice (Peromyscus maniculatus) with recently acquired Sin Nombre virus (SNV) infections is an indicator of epizootic intensity and may be key in predicting outbreaks of hantavirus cardio-pulmonary syndrome in humans. We investigated whether incidence of recent infections was related to season, sex, reproductive status, or habitat ...
M Denise, Dearing +4 more
openaire +2 more sources
Hantaviruses are rodent-borne viruses that cause severe disease in infected humans. In the New World, major hantaviruses include Andes virus (ANDV) and Sin Nombre virus (SNV) causing hantavirus pulmonary syndrome.
Rebecca L. Brocato +10 more
doaj +1 more source
Background All viruses in the family Bunyaviridae possess a tripartite genome, consisting of a small, a medium, and a large RNA segment. Bunyaviruses therefore possess considerable evolutionary potential, attributable to both intramolecular changes and ...
Calisher Charles H +4 more
doaj +1 more source
Plasma Exchange for Hantavirus Pulmonary Syndrome: A Mechanistic Case for an Untested Intervention
ABSTRACT Hantavirus pulmonary syndrome (HPS) carries a case fatality rate of 35%–40% and has no approved pharmacologic treatment. Its pathophysiology is rooted in the plasma compartment: cytokines, viral antigens, immune complexes, and platelet‐binding glycoproteins circulate as drivers of immunopathologic endothelial injury, noncardiogenic pulmonary ...
Menatalla Nadim +2 more
wiley +1 more source
Temporal and Spatial Analysis of Sin Nombre Virus Quasispecies in Naturally Infected Rodents [PDF]
ABSTRACT Sin Nombre virus (SNV) is thought to establish a persistent infection in its natural reservoir, the deer mouse ( Peromyscus maniculatus ), despite a strong host immune response. SNV-specific neutralizing antibodies were routinely detected in deer mice which maintained virus RNA in the blood and ...
R, Feuer +4 more
openaire +2 more sources
Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease
Rodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Giuseppe Gallo +2 more
wiley +1 more source

