Thottapalayam virus is genetically distant to the rodent-borne hantaviruses, consistent with its isolation from the Asian house shrew (Suncus murinus) [PDF]
Thottapalayam (TPM) virus belongs to the genus Hantavirus, family Bunyaviridae. The genomes of hantaviruses consist of three negative-stranded RNA segments (S, M and L) encoding the virus nucleocapsid (N), glycoprotein (Gn, Gc), and polymerase (L ...
Pragya D Yadav +2 more
core +1 more source
Zusammenfassung Hintergrund Kutane nichttuberkulöse Mykobakterien‐Infektionen (NTM) sind diagnostisch und therapeutisch herausfordernd. Ziel dieser Studie war die Charakterisierung kutaner NTM‐Infektionen in Deutschland über einen Zeitraum von 24 Jahren. Patienten und Methodik Eingeschlossen wurden 73 Patienten mit kutanen NTM‐Infektionen, die zwischen
Luisa Bopp +6 more
wiley +1 more source
Entomological characterization of malaria in northern Colombia through vector and parasite species identification, and analyses of spatial distribution and infection rates [PDF]
Background: Malaria remains a worldwide public health concern and, in Colombia, despite the efforts to stop malaria transmission, the incidence of cases has increased over the last few years. In this context, it is necessary to evaluate vector diversity,
Gonzalez C. +8 more
core +1 more source
Neoadjuvante Therapie bei Hautkrebs: aktuelle Datenlage und Ausblicke
Zusammenfassung Die Entwicklung von Immuncheckpoint‐Inhibitoren sowie zielgerichteten Therapien hat die Behandlung von Hauttumoren, vor allem des kutanen Plattenepithelkarzinoms, Melanoms und Merkelzellkarzinoms, grundlegend verändert. Neuste neoadjuvante Ansätze zeigen besonders bei lokal fortgeschrittenen Stadien nun praxisrelevante Ergebnisse.
Lea Daniello +2 more
wiley +1 more source
Summary: New World hantaviruses (NWHs) are endemic in North and South America and cause hantavirus cardiopulmonary syndrome (HCPS), with a case fatality rate of up to 40%. Knowledge of the natural humoral immune response to NWH infection is limited. Here,
Taylor B. Engdahl +15 more
doaj +1 more source
Community perceptions of free-roaming dogs and management practices in villages at the periphery of a protected area in Bhutan [PDF]
In Bhutan, free-roamingdogs pose health hazards to human, livestock, andwildlife. Understanding the perceptions and practices of local communitiesregarding free-roaming dogs is important to mitigate negative impacts. A community-based study was conducted
De Garine-Wichatitsky, Michel +4 more
core +1 more source
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova +6 more
wiley +1 more source
Neutralizing Antibodies in Survivors of Sin Nombre and Andes Hantavirus Infection
We evaluated titers of homotypic and heterotypic neutralizing antibodies (NAbs) to Andes and Sin Nombre hantaviruses in plasma samples from 20 patients from Chile and the United States. All but 1 patient had high titers of NAb. None of the plasma samples
Francisca Valdivieso +6 more
doaj +1 more source
Of voles and men: novel Hantavirus in vitro models [PDF]
Hantavirus-infection can cause severe disease in humans, with up to 40% case fatalities. Presently, no therapeutics or prophylaxis against hantaviral illness exists.
Sundström, Karin
core +1 more source
Helminths as architects of trained tolerance: implications for human health
Abstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Quinn Moroz +2 more
wiley +1 more source

