Results 31 to 40 of about 4,245 (147)

“Super-Spreaders” and Person-to-Person Transmission of Andes Virus in Argentina

New England Journal of Medicine, 2020
From November 2018 through February 2019, person-to-person transmission of Andes virus (ANDV) hantavirus pulmonary syndrome occurred in Chubut Province, Argentina, and resulted in 34 confirmed infections and 11 deaths. Understanding the genomic, epidemiologic, and clinical characteristics of person-to-person transmission of ANDV is crucial to designing
Martínez, Valeria P., Di Paola, Nicholas, Alonso, Daniel O., Pérez-Sautu, Unai, Bellomo, Carla M., Iglesias, Ayelén A., Coelho, Rocio M., López, Beatriz, Periolo, Natalia, Larson, Peter A., Nagle, Elyse R., Chitty, Joseph A., Pratt, Catherine B., Díaz, Jorge, Cisterna, Daniel, Campos, Josefina, Sharma, Heema, Dighero-Kemp, Bonnie, Biondo, Emiliano, Lewis, Lorena, Anselmo, Constanza, Olivera, Camila P., Pontoriero, Fernanda, Lavarra, Enzo, Kuhn, Jens H., Strella, Teresa, Edelstein, Alexis, Burgos, Miriam I., Kaler, Mario, Rubinstein, Adolfo, Kugelman, Jeffrey R., Sanchez-Lockhart, Mariano, Perandones, Claudia, Palacios, Gustavo   +33 more
openaire   +3 more sources

Knowledge, attitudes, and practices regarding hantavirus disease and acceptance of a vaccine trial in rural communities of southern Chile

Human Vaccines & Immunotherapeutics, 2017
Andes hantavirus cardiopulmonary syndrome, transmitted by Oligoryzomys longicaudatus, has no approved treatment, a case fatality rate of 35%, and documented person-to-person transmission. An Andes vaccine, highly needed for prevention, is in development.
Francisca Valdivieso, Claudia Gonzalez, Manuel Najera, Andrea Olea, Analia Cuiza, Ximena Aguilera, Gregory Mertz   +6 more
doaj   +1 more source

Zoonotic Hantaviridae with Global Public Health Significance

Viruses, 2023
Hantaviridae currently encompasses seven genera and 53 species. Multiple hantaviruses such as Hantaan virus, Seoul virus, Dobrava-Belgrade virus, Puumala virus, Andes virus, and Sin Nombre virus are highly pathogenic to humans.
Rui-Xu Chen, Huan-Yu Gong, Xiu Wang, Ming-Hui Sun, Yu-Fei Ji, Su-Mei Tan, Ji-Ming Chen, Jian-Wei Shao, Ming Liao   +8 more
doaj   +1 more source

Phylogenetics and Evolution of Potato Virus V: Another Potyvirus that Originated in the Andes

Plant Disease, 2022
Potato virus V (PVV) causes a disease of potato (Solanum tubersosum) in South and Central America, Europe, and the Middle East. We report here the complete genomic sequences of 42 new PVV isolates from the potato’s Andean domestication center in Peru and of eight historical or recent isolates from Europe. When the principal open reading frames of these
Fuentes, Segundo, Gibbs, Adrian J, Adams, Ian P, Hajizadeh, Mohammad, Kreuze, Jan, Fox, Adrian, Blouin, Arnaud, Jones, Roger A C   +7 more
openaire   +3 more sources

Proteinuria in Hantavirus Cardiopulmonary Syndrome: A Frequent Finding Linked To Mortality

International Journal of Infectious Diseases, 2021
Objectives: To determine the relative frequency and prognosis value of proteinuria in hantavirus cardiopulmonary syndrome (HCPS) due to Andes virus. Methods: This observational analytical study prospectively obtained data from patients admitted to 12 ...
René López, Mauricio Espinoza, Jerónimo Graf, Gregory Mertz, Marcela Ferrés, Mario Calvo, Cecilia Vial, Pablo A. Vial   +7 more
doaj   +1 more source

Vesicular Stomatitis Virus-Based Vaccine Protects Hamsters against Lethal Challenge with Andes Virus [PDF]

Journal of Virology, 2011
ABSTRACT Andes virus (ANDV) is a highly pathogenic South American hantavirus that causes hantavirus pulmonary syndrome (HPS). A high case fatality rate, the potential for human-to-human transmission, the capacity to infect via aerosolization, and the absence of effective therapies make it imperative that a safe, fast-acting, and ...
Kyle S, Brown, David, Safronetz, Andrea, Marzi, Hideki, Ebihara, Heinz, Feldmann   +4 more
openaire   +2 more sources

Novel infection of pericytes by Andes virus enhances endothelial cell permeability

Virus Research, 2021
Andes Virus (ANDV) non-lytically infects pulmonary microvascular endothelial cells (PMECs) causing a severe capillary leak syndrome termed Hantavirus Pulmonary Syndrome (HPS). Basolaterally, PMECs are in contact with pericytes which play critical roles in regulating PMEC permeability and immune cell recruitment.
Ramon D. Perez, Elena E. Gorbonova, Erich R. Mackow   +2 more
openaire   +2 more sources

Chloroquine, an Anti-Malaria Drug as Effective Prevention for Hantavirus Infections

Frontiers in Cellular and Infection Microbiology, 2021
We investigated whether chloroquine can prevent hantavirus infection and disease in vitro and in vivo, using the Hantaan virus newborn C57BL/6 mice model and the Syrian hamster model for Andes virus.
Valentijn Vergote, Lies Laenen, Raf Mols, Patrick Augustijns, Marc Van Ranst, Piet Maes   +5 more
doaj   +1 more source

Sin Nombre Virus and the Emergence of Other Hantaviruses: A Review of the Biology, Ecology, and Disease of a Zoonotic Pathogen

Biology, 2023
Sin Nombre virus (SNV) is an emerging virus that was first discovered in the Four Corners region of the United States in 1993. The virus causes a disease known as Hantavirus Pulmonary Syndrome (HPS), sometimes called Hantavirus Cardiopulmonary Syndrome ...
Andrew T. Jacob, Benjamin M. Ziegler, Stefania M. Farha, Lyla R. Vivian, Cora A. Zilinski, Alexis R. Armstrong, Andrew J. Burdette, Dia C. Beachboard, Christopher C. Stobart   +8 more
doaj   +1 more source

Evidence of hantavirus infection in wild rodents captured in a rural area of the state of São Paulo, Brazil Evidência de infecção por hantavírus em roedores silvestres capturados em uma área rural do estado de São Paulo, Brasil

Pesquisa Veterinária Brasileira, 2004
Hantaviruses are the etiological agents of the Hantavirus Cardio-Pulmonary Syndrome, a serious rodent-borne disease in Brazil. In order to investigate the occurrence of hantavirus infection in wild rodents, a survey was conducted in three different ...
Elba Regina S. de Lemos, Paulo S. D'Andrea, Cibele R. Bonvicino, Kátia M. Famadas, Paula Padula, Adauto A. Cavalcanti, Hermann G. Schatzmayr   +6 more
doaj   +1 more source