Virological characterization of a new isolated strain of Andes virus involved in the recent person-to-person transmission outbreak reported in Argentina. [PDF]
PLoS Neglected Tropical DiseasesOn November 2, 2018, a person-to-person transmission outbreak of Andes virus (Orthohantavirus andesense) began in the small town of Epuyén, Argentina. The strain demonstrated a high capacity for sustained transmission among the human population requiring
Rocio Coelho +10 more
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Neutralizing Monoclonal Antibodies against the Gn and the Gc of the Andes Virus Glycoprotein Spike Complex Protect from Virus Challenge in a Preclinical Hamster Model [PDF]
mBio, 2020 Hantaviruses are the etiological agent of hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The latter is associated with case fatality rates ranging from 30% to 50%.
James Duehr +10 more
doaj +4 more sources
The Major Cellular Sterol Regulatory Pathway Is Required for Andes Virus Infection [PDF]
PLoS Pathogens, 2014 The Bunyaviridae comprise a large family of RNA viruses with worldwide distribution and includes the pathogenic New World hantavirus, Andes virus (ANDV). Host factors needed for hantavirus entry remain largely enigmatic and therapeutics are unavailable.
Emily Bruce, Paul Bates, Fang-Hua Lee
exaly +6 more sources
Therapeutic Efficacy of Human Monoclonal Antibodies against Andes Virus Infection in Syrian Hamsters [PDF]
Emerging Infectious Diseases, 2021 Andes virus, an orthohantavirus endemic to South America, causes severe hantavirus cardiopulmonary syndrome associated with human-to-human transmission. No approved treatments or vaccines against this virus are available.
Brandi N. Williamson +5 more
doaj +2 more sources
Transmission potential of Andes virus from human to human [PDF]
New Microbes and New InfectionsHiroshi Nishiura, Yuri Amemiya
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Viruses, 2019 Andes virus (ANDV) and Sin Nombre virus (SNV) are the main causative agents responsible for hantavirus cardiopulmonary syndrome (HCPS) in the Americas.
Bryce M Warner +9 more
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Host mTORC1 Signaling Regulates Andes Virus Replication [PDF]
Journal of Virology, 2013 ABSTRACT Hantavirus pulmonary syndrome (HPS) is a severe respiratory disease characterized by pulmonary edema, with fatality rates of 35 to 45%. Disease occurs following infection with pathogenic New World hantaviruses, such as Andes virus (ANDV), which targets lung microvascular endothelial cells.
Shannon, McNulty +3 more
openaire +3 more sources
New Andes virus isolate haplotype obtained during prospective close contacts follow-up of an Hantavirus cardiopulmonary syndrome fatal case, Chile [PDF]
Current Research in Microbial SciencesAndes virus (ANDV) is a zoonotic orthohantavirus that causes hantavirus cardiopulmonary syndrome. Transmission occurs mainly through contact with infected rodent excreta and, less frequently, between humans. Viral isolation from human samples is rare; in
Aldo Barrera +11 more
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Hantavirus pulmonary syndrome: encephalitis caused by virus Andes
Journal of NeuroVirology, 2011 Hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome (HPS) are rodent-borne emerging diseases caused by members of the genus Hantavirus, family Bunyaviridae. Some species of hantavirus may cause encephalitis, but this is the first report in Andes virus associated to HPS.
Talamonti, Lionel +5 more
exaly +4 more sources
In Vitro and In Vivo Activity of Ribavirin against Andes Virus Infection
PLoS ONE, 2011 Pathogenic hantaviruses are a closely related group of rodent-borne viruses which are responsible for two distinct diseases in humans, hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome (HPS, otherwise known as hantavirus cardiopulmonary syndrome, HCPS). The antiviral effect of ribavirin against Old World hantaviruses, most notably
Heinz Feldmann +2 more
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