Results 1 to 10 of about 15,102 (162)

Syrian hamster as an ideal animal model for evaluation of cancer immunotherapy [PDF]

Frontiers in Immunology, 2023
Cancer immunotherapy (CIT) has emerged as an exciting new pillar of cancer treatment. Although benefits have been achieved in individual patients, the overall response rate is still not satisfactory. To address this, an ideal preclinical animal model for
Yangyang Jia, Lemoine Nicholas R, Wang Pengju   +2 more
exaly   +4 more sources

Golden Syrian Hamster Models for Cancer Research [PDF]

Cells, 2022
The golden Syrian hamster (Mesocricetus auratus) has long been a valuable rodent model of human diseases, especially infectious and metabolic diseases. Hamsters have also been valuable models of several chemically induced cancers such as the DMBA-induced
Zhongde Wang, Wang Zhongde
exaly   +4 more sources

Histopathologic Characterization of Experimental Peracute SARS-CoV-2 Infection in the Syrian Hamster [PDF]

Veterinary Sciences, 2023
Coronavirus Infectious Disease 2019 (COVID-19) initiated a global pandemic that thus far has resulted in the death of over 6.5 million people internationally.
Chad S. Clancy, Kimberly Meade-White, Carl Shaia, Greg Saturday, Heinz Feldmann, Kyle Rosenke   +5 more
doaj   +2 more sources

Genomic-transcriptomic analysis identifies the Syrian hamster as a superior animal model for human diseases [PDF]

BMC Genomics
Background The Syrian hamster (Mesocricetus auratus) has shown promise as a human diseases model, recapitulating features of different human diseases including COVID-19.
Chuchu Wang, Zhenguo Cheng, Jinxin Miao, Xia Xue, Yunshu Dong, Li Zhao, Haoran Guo, Jianyao Wang, Zhizhong Wang, Shuangshuang Lu, Guangming Fang, Ying Peng, Yafei Zhai, Zhongxian Zhang, Dongling Gao, Zhimin Wang, Pengju Wang, Lirong Zhang, Louisa S Chard Dunmall, Jun Wang, Wenxue Tang, Xiaowei Li, Zhongren Ding, Xiaoyan Zhao, Ling Li, Nicholas R. Lemoine, Zhongde Wang, Daniel Tonge, Wenjie Tan, Jianzeng Dong, Yaohe Wang   +30 more
doaj   +2 more sources

Syrian Hamster as an Animal Model for the Study on Infectious Diseases

Frontiers in Immunology, 2019
Infectious diseases still remain one of the biggest challenges for human health. In order to gain a better understanding of the pathogenesis of infectious diseases and develop effective diagnostic tools, therapeutic agents, and preventive vaccines, a ...
Jinxin Miao, Louisa S Chard, Zhimin Wang   +2 more
exaly   +3 more sources

Pathology and host-pathogen interactions in a golden Syrian hamster model of Nipah virus infection [PDF]

Frontiers in Veterinary Science
Nipah virus (NiV) is recognized as one of the key pathogens with pandemic potential. We have recently established a NiV hamster model, which reproduces a highly similar disease to that observed in human cases, including respiratory and neurological signs
Inés Ruedas-Torres, Stephen Findlay-Wilson, Emma Kennedy, Stuart Dowall, Francisco Javier Salguero   +4 more
doaj   +2 more sources

Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting

Frontiers in Immunology, 2023
IntroductionImmune checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer, but preclinical testing of hypotheses such as combination therapies has been complicated, in part due to species incompatibility issues.
James H. A. Clubb, James H. A. Clubb, James H. A. Clubb, Tatiana V. Kudling, Tatiana V. Kudling, Mykhailo Girych, Lyna Haybout, Lyna Haybout, Santeri Pakola, Santeri Pakola, Firas Hamdan, Firas Hamdan, Víctor Cervera-Carrascon, Víctor Cervera-Carrascon, Víctor Cervera-Carrascon, Annabrita Hemmes, Susanna Grönberg-Vähä-Koskela, Susanna Grönberg-Vähä-Koskela, Susanna Grönberg-Vähä-Koskela, João Manuel Santos, João Manuel Santos, João Manuel Santos, Dafne C. A. Quixabeira, Dafne C. A. Quixabeira, Dafne C. A. Quixabeira, Saru Basnet, Saru Basnet, Camilla Heiniö, Camilla Heiniö, Victor Arias, Victor Arias, Elise Jirovec, Elise Jirovec, Shreyas Kaptan, Riikka Havunen, Riikka Havunen, Riikka Havunen, Suvi Sorsa, Suvi Sorsa, Suvi Sorsa, Abdullah Erikat, Joel Schwartz, Marjukka Anttila, Katri Aro, Katri Aro, Tapani Viitala, Ilpo Vattulainen, Vincenzo Cerullo, Vincenzo Cerullo, Anna Kanerva, Akseli Hemminki, Akseli Hemminki, Akseli Hemminki, Akseli Hemminki   +53 more
doaj   +1 more source

Sequencing, annotation and analysis of the Syrian hamster (Mesocricetus auratus) transcriptome. [PDF]

PLoS ONE, 2014
BACKGROUND:The Syrian hamster (golden hamster, Mesocricetus auratus) is gaining importance as a new experimental animal model for multiple pathogens, including emerging zoonotic diseases such as Ebola.
Nicolas Tchitchek, David Safronetz, Angela L Rasmussen, Craig Martens, Kimmo Virtaneva, Stephen F Porcella, Heinz Feldmann, Hideki Ebihara, Michael G Katze   +8 more
doaj   +1 more source

Chondroma of the foreleg in a Syrian hamster [PDF]

Laboratory Animals, 1993
A spontaneous bone tumour in the foreleg of a Syrian hamster was shown to be a chondroma; this is only the second report of such a tumour and the first described in detail.
P, Brown, J, Henderson, T, Hilton, J, Parren   +3 more
openaire   +2 more sources

The SARS-CoV-2 Alpha variant exhibits comparable fitness to the D614G strain in a Syrian hamster model

Communications Biology, 2022
The SARS-CoV-2 Alpha variant exhibits similar transmission dynamics to an ancestral D614G variant in a Syrian hamster model, suggesting the limitations of using the hamster as the sole model to assess differences between SARS-CoV-2 strains.
Maxime Cochin, Léa Luciani, Franck Touret, Jean-Sélim Driouich, Paul-Rémi Petit, Grégory Moureau, Cécile Baronti, Caroline Laprie, Laurence Thirion, Piet Maes, Robbert Boudewijns, Johan Neyts, Xavier de Lamballerie, Antoine Nougairède   +13 more
doaj   +1 more source