Results 31 to 40 of about 106,611 (161)

The ventral striatum of the Syrian hamster

, 1999
The Syrian hamster, Mesocricetus auratus, was first used in laboratory experiments some fifty years ago in the Middle East, from animals captured in the wild.
LUKE R. JOHNSON, Wood, Ruth I., Johnson, Luke R., RUTH I. WOOD   +3 more
core   +1 more source

Insulin deficiency and reduced expression of lipogenic enzymes in cardiomyopathic hamster

Journal of Lipid Research, 2001
Evidence is given that the heart of the cardiomyopathic UM-X7.1 hamster has a lipid composition different from that of the same tissue isolated from animals of the Syrian hamster parent strain.
Alba Vecchini, Luciano Binaglia, Marc Bibeau, Marilena Minieri, Felicia Carotenuto, Paolo Di Nardo   +5 more
doaj   +1 more source

Generation and characterization of an Il2rg knockout Syrian hamster model for XSCID and HAdV-C6 infection in immunocompromised patients

Disease Models & Mechanisms, 2020
Model animals are indispensable for the study of human diseases, and in general, of complex biological processes. The Syrian hamster is an important model animal for infectious diseases, behavioral science and metabolic science, for which more ...
Rong Li, Baoling Ying, Yanan Liu, Jacqueline F. Spencer, Jinxin Miao, Ann E. Tollefson, James D. Brien, Yaohe Wang, William S. M. Wold, Zhongde Wang, Karoly Toth   +10 more
doaj   +1 more source

Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2

Nature Communications, 2021
Until today effective antivirals for COVID-19 treatment are not widely available. Here, Zhao et al. characterize a dual-functional cross-linking peptide, 8P9R, that can inhibit SARS-CoV-2 virus entry in vitro and suppresses viral replication in vivo in ...
Hanjun Zhao, Kelvin K. W. To, Hoiyan Lam, Xinxin Zhou, Jasper Fuk-Woo Chan, Zheng Peng, Andrew C. Y. Lee, Jianpiao Cai, Wan-Mui Chan, Jonathan Daniel Ip, Chris Chung-Sing Chan, Man Lung Yeung, Anna Jinxia Zhang, Allen Wing Ho Chu, Shibo Jiang, Kwok-Yung Yuen   +15 more
doaj   +1 more source

Conformational Stability of Syrian Hamster Prion Protein PrP(90−231)

, 2016
Conformational Stability of Syrian Hamster Prion Protein PrP(90 ...
Teresa J. T. Pinheiro (198296), Michael T. Bowers (252202), Megan Grabenauer (2068348), Narinder Sanghera (510849), James H. Scrivens (1727059), Susan E. Slade (2047675), Thomas Wyttenbach (1564150)   +6 more
core   +1 more source

Comprehensive Transcriptome Analyses of the Fructose-Fed Syrian Golden Hamster Liver Provides Novel Insights into Lipid Metabolism. [PDF]

PLoS ONE, 2016
Dyslipidemia has been widely proven to contribute to cardiovascular diseases and other metabolic disorders, especially in insulin resistance and type 2 diabetes.
Ziyang Li, Chaoliang Xiong, Suo Mo, Haiying Tian, Mengqian Yu, Tingting Mao, Qian Chen, Haitao Luo, Quanzhen Li, Jianxin Lu, Yi Zhao, Wei Li   +11 more
doaj   +1 more source

Kisspeptins and RFRP-3 act in concert to synchronize rodent reproduction with seasons

Frontiers in Neuroscience, 2013
Seasonal mammals use the photoperiodic variation in the nocturnal production of the pineal hormone melatonin to synchronize their reproductive activity with seasons. In rodents, the short day profile of melatonin secretion has long been proven to inhibit
Valerie eSimonneaux, Caroline eAncel, François eGauer, Vincent-Joseph ePoirel   +3 more
doaj   +1 more source

History and prospects of intracytoplasmic sperm injection (ICSI) and the development of golden hamster ICSI embryos

Reproductive Medicine and Biology, 2021
Background Golden (Syrian) hamsters have many advantages for the study of reproductive biology and developmental biology, including a consistent estrous cycle, a stable superovulation response, and a short gestation period.
Nami Morishita, Masanori Ochi, Toshitaka Horiuchi   +2 more
doaj   +1 more source

Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection

Nature Communications, 2021
Here, Ferren et al. isolate Syrian hamster brainstem and lung tissue to establish ex vivo culture systems to study SARS-CoV-2 local viral tropism, immune response and tissue pathology.
Marion Ferren, Valérie Favède, Didier Decimo, Mathieu Iampietro, Nicole A. P. Lieberman, Jean-Luc Weickert, Rodolphe Pelissier, Magalie Mazelier, Olivier Terrier, Anne Moscona, Matteo Porotto, Alexander L. Greninger, Nadia Messaddeq, Branka Horvat, Cyrille Mathieu   +14 more
doaj   +1 more source

An Oral Antiviral Combination Against Severe COVID‐19 Enabled by the Synergistic Mechanisms of Action of Auranofin and Remdesivir

Advanced Science, EarlyView.
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun, Rohan Narayan, Santhosh Kambaiah Nagaraj, Rishad Shiraz, Abinaya Kaliappan, Sumandeep Kaur, Ankur Singh, Siva Shanmugam Selvaraj, Gudepalya Renukaiah Rudramurthy, Chakenahalli Naveenkumar, Shridhar Narayanan, Radha Krishan Shandil, Shailly Tomar, Shashank Tripathi   +13 more
wiley   +1 more source