Results 51 to 60 of about 106,611 (161)
Hitting Coronaviruses Where It Hurts: Antiviral Strategies Targeting Viral Proteins
ChemMedChem, Volume 21, Issue 19, 14 October 2026.Viral proteins represent key vulnerabilities in human coronaviruses (HCoVs). This review outlines inhibitors targeting spike (S), main protease (Mpro), papain‐like protease (PLpro), and RNA‐dependent RNA polymerase (RdRp), mapping chemically diverse strategies that disrupt entry and replication, and provides an integrated view of current candidates ...
Álvaro de la Cruz‐Potenciano +3 more
wiley +1 more source
The Golgi Apparatus of Neocortical Glial Cells During Hibernation in the Syrian Hamster
Frontiers in Neuroanatomy, 2019 Hibernating mammals undergo torpor periods characterized by a general decrease in body temperature, metabolic rate, and brain activity accompanied by complex adaptive brain changes that appear to protect the brain from extreme conditions of hypoxia and ...
Gonzalo León-Espinosa +7 more
doaj +1 more source
Animal Models and Experimental Medicine, Volume 9, Issue 10, Page 2063-2074, October 2026.We established ABCA1‐knockout Syrian golden hamsters as a novel and physiologically relevant model for colitis research. When challenged with a high‐fat diet, ABCA1‐deficient hamsters developed exacerbated colonic inflammation and impaired mucosal barrier integrity, driven by intracellular cholesterol accumulation.
Chang Liu +10 more
wiley +1 more source
MOESM1 of DNA double-strand break repair is impaired in presenescent Syrian hamster fibroblasts
, 2016 Additional file 1: Figure S1. Detection of β-galactosidase activity in Syrian hamster early- and late-passage cells and human fibroblasts of different age.
Andrey Kropotov (3418292) +6 more
core +1 more source
The Syrian War: religious & political representations [PDF]
, 2014 Issue title: Preludes to the Islamic State: contextualizing the rise of extremism in the Syrian UprisingThe analysis of the social media content of: Syrian & foreign - opposition & loyalist - official & informal will allow us to understand the extent to
Valter, Stéphane
core +1 more source
All LifeAnimal models have historically played a crucial role in understanding emerging infectious diseases and developing preventive measures such as vaccines and therapeutics.
Biruh Mebratu Belay +3 more
doaj +1 more source
Protein O‐Glycosylation Shapes Lymphatic Endothelia and Lymph Node Macrophage Populations
The FASEB Journal, Volume 40, Issue 18, 30 September 2026.To study the functional roles of O‐glycans on lymphatic endothelia, we deleted Cosmc, the chaperone required for core‐1 O‐glycan synthesis. Loss of core‐1 O‐glycans entailed major changes in glycoprotein composition of lymphatic endothelial cells (LEC), including reduced podoplanin (Pdpn), CD44, and Lyve‐1, and increased ICAM‐1; reduced CD44 was caused
Jasmin Frey +11 more
wiley +1 more source
Deep Learning‐Based Monitoring of European Hamster Activity
Ecology and Evolution, Volume 16, Issue 9, September 2026.We evaluated the use of a deep learning‐based object detection model (YOLO) to automate camera trap video analysis for monitoring the activity of the critically endangered European hamster (Cricetus cricetus). The AI‐based approach achieved high agreement with human assessments (F1‐score and accuracy of 0.93) and reliably detected temporal activity ...
Marie Wittekind +2 more
wiley +1 more source
Biology, 2019 During hibernation, repeated cycles of ischemia-reperfusion (I-R) leave vital organs without injury. Studying this phenomenon may reveal pathways applicable to improving outcomes in I-R injury-induced human diseases.
Theodoros Eleftheriadis +4 more
doaj +1 more source
Reviews in Medical Virology, Volume 36, Issue 5, September 2026.ABSTRACT Hantaviruses are emerging zoonotic pathogens of increasing global public health significance. Their epidemiological landscape is rapidly changing due to ecological disruption, climate variability, urbanisation, and evolving human–animal interfaces.
Francesco De Maria +5 more
wiley +1 more source