Results 41 to 50 of about 15,106 (130)

Metabolic Reprogramming and GM‐CSF Secretion in Areca Nut‐Activated Fibroblasts Drive Oral Precancer Progression

Oral Diseases, EarlyView.
ABSTRACT Objective Oral cancer, with a rising global incidence and poor prognosis, is associated with areca nut use in South and Southeast Asia. In this study, we addressed the effects of areca nut extract (ANE) on oral carcinogenesis by modulating fibroblast behavior in oral tissue.
Yen‐Yun Wang, Chang‐Wei Su, Chih‐Huang Tseng, Pang‐Yu Chen, Hieu D. H. Nguyen, Leong‐Perng Chan, Yuk‐Kwan Chen, Shih Sheng Jiang, Steven Lo, Shyng‐Shiou F. Yuan   +9 more
wiley   +1 more source

The Changing Landscape of Hantavirus Infections: A Narrative Review of Epidemiology, Pathogenesis, and Countermeasures

Reviews in Medical Virology, Volume 36, Issue 5, September 2026.
ABSTRACT Hantaviruses are emerging zoonotic pathogens of increasing global public health significance. Their epidemiological landscape is rapidly changing due to ecological disruption, climate variability, urbanisation, and evolving human–animal interfaces.
Francesco De Maria, Francesco Branda, Giancarlo Ceccarelli, Fabio Scarpa, Massimo Ciccozzi, Alessandro Russo   +5 more
wiley   +1 more source

The Golgi Apparatus of Neocortical Glial Cells During Hibernation in the Syrian Hamster

Frontiers in Neuroanatomy, 2019
Hibernating mammals undergo torpor periods characterized by a general decrease in body temperature, metabolic rate, and brain activity accompanied by complex adaptive brain changes that appear to protect the brain from extreme conditions of hypoxia and ...
Gonzalo León-Espinosa, Gonzalo León-Espinosa, Javier DeFelipe, Javier DeFelipe, Javier DeFelipe, Alberto Muñoz, Alberto Muñoz, Alberto Muñoz   +7 more
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, Volume 16, Issue 8, Page 1477-1490, August 2026.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Review on the current status of Syrian hamsters as an animal model for COVID-19 transmission, pathogenesis, treatment and vaccine research

All Life
Animal models have historically played a crucial role in understanding emerging infectious diseases and developing preventive measures such as vaccines and therapeutics.
Biruh Mebratu Belay, Abebe Tesfaye Gessese, Mebrie Zemene Kinde, Gashaw Getaneh Dagnaw   +3 more
doaj   +1 more source

Models of Oral Epithelial Dysplasia: A Systematic Review and Temporal Analysis

Journal of Oral Pathology &Medicine, Volume 55, Issue 7, Page 755-773, August 2026.
ABSTRACT Background Oral squamous cell carcinoma (OSCC) is the most common malignancy of the head and neck, associated with substantial morbidity and mortality worldwide. Oral epithelial dysplasia (OED) can precede OSCC, offering a critical window for preventive and therapeutic intervention.
Zilefac Brian Ngokwe, Satutya Wicaksono, Michael McCullough, Antonio Celentano, Tami Yap   +4 more
wiley   +1 more source

Using a Syrian (Golden) Hamster Biological Model for the Evaluation of Recombinant Anthrax Vaccines

Life, 2021
In this paper, we demonstrate that a Syrian hamster biological model can be applied to the study of recombinant anthrax vaccines. We show that double vaccination with recombinant proteins, such as protective antigen (PA) and fusion protein LF1PA4 ...
Tatiana Kravchenko, Galina Titareva, Irina Bakhteeva, Tatiana Kombarova, Alexander Borzilov, Raisa Mironova, Kseniya Khlopova, Vitalii Timofeev   +7 more
doaj   +1 more source

The Neural Distribution of Vasotocin, Oxytocin, Dopamine, and Serotonin in Two Australian Skinks With Contrasting Social Lives

Journal of Comparative Neurology, Volume 534, Issue 7, July 2026.
1. We investigated two skink species differing primarily in social ecology. 2. Using immunohistochemistry, we investigated the distribution of four neurotransmitters known to play a role in vertebrate social behavior. 3. We generally found these transmitters in more brain regions in the family‐living species.
Jai Lake, Martin J. Whiting, Geoffrey M. While, David Kabelik, Dustin R. Rubenstein, Daniel Hoops   +5 more
wiley   +1 more source

The H2S–Nrf2–Antioxidant Proteins Axis Protects Renal Tubular Epithelial Cells of the Native Hibernator Syrian Hamster from Reoxygenation-Induced Cell Death

Biology, 2019
During hibernation, repeated cycles of ischemia-reperfusion (I-R) leave vital organs without injury. Studying this phenomenon may reveal pathways applicable to improving outcomes in I-R injury-induced human diseases.
Theodoros Eleftheriadis, Georgios Pissas, Evdokia Nikolaou, Vassilios Liakopoulos, Ioannis Stefanidis   +4 more
doaj   +1 more source

Efficient gene targeting in golden Syrian hamsters by the CRISPR/Cas9 system. [PDF]

PLoS ONE, 2014
The golden Syrian hamster is the model of choice or the only rodent model for studying many human diseases. However, the lack of gene targeting tools in hamsters severely limits their use in biomedical research.
Zhiqiang Fan, Wei Li, Sang R Lee, Qinggang Meng, Bi Shi, Thomas D Bunch, Kenneth L White, Il-Keun Kong, Zhongde Wang   +8 more
doaj   +1 more source