Results 61 to 70 of about 106,611 (161)

Efficient gene targeting in golden Syrian hamsters by the CRISPR/Cas9 system. [PDF]

open access: yesPLoS ONE, 2014
The golden Syrian hamster is the model of choice or the only rodent model for studying many human diseases. However, the lack of gene targeting tools in hamsters severely limits their use in biomedical research.
Zhiqiang Fan   +8 more
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, Volume 16, Issue 8, Page 1477-1490, August 2026.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

MOESM5 of DNA double-strand break repair is impaired in presenescent Syrian hamster fibroblasts

open access: yes, 2016
Additional file 5: Table S1. Colocalization of gH2AX with 53BP1, DNA-PK, pATM and p-ATM/ATR substrates in Syrian hamster fibroblasts at two time points after BL ...
Andrey Kropotov (3418292)   +6 more
core   +1 more source

Strategies for inducing diabetes in laboratory animals: Advances from chemical, surgical, immunologic, dietary, and genetic approaches

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 8, Page 1548-1566, August 2026.
This review summarizes the principal experimental approaches used to induce diabetes in animal models. Strategies include chemical agents (streptozotocin, alloxan, dithizone, gold thioglucose), dietary interventions (high‐fat and high‐sugar diets), surgical methods (total or partial pancreatectomy), genetic models (db/db, ob/ob, Goto‐Kakizaki [GK ...
Milad Faraji   +2 more
wiley   +1 more source

A Case Report in a Syrian Hamster with Hyperadrenocorticism Diagnosed and Treated with Therapeutic Trial

open access: yesFolia Veterinaria, 2022
This case report describes a practical approach for diagnosing and treating a 17-month-old Syrian hamster with hyperadrenocorticism based on: history, systemic signs, dermatological lesions, and therapeutic trial.
Petrou P.
doaj   +1 more source

Models of Oral Epithelial Dysplasia: A Systematic Review and Temporal Analysis

open access: yesJournal of Oral Pathology &Medicine, Volume 55, Issue 7, Page 755-773, August 2026.
ABSTRACT Background Oral squamous cell carcinoma (OSCC) is the most common malignancy of the head and neck, associated with substantial morbidity and mortality worldwide. Oral epithelial dysplasia (OED) can precede OSCC, offering a critical window for preventive and therapeutic intervention.
Zilefac Brian Ngokwe   +4 more
wiley   +1 more source

The Neural Distribution of Vasotocin, Oxytocin, Dopamine, and Serotonin in Two Australian Skinks With Contrasting Social Lives

open access: yesJournal of Comparative Neurology, Volume 534, Issue 7, July 2026.
1. We investigated two skink species differing primarily in social ecology. 2. Using immunohistochemistry, we investigated the distribution of four neurotransmitters known to play a role in vertebrate social behavior. 3. We generally found these transmitters in more brain regions in the family‐living species.
Jai Lake   +5 more
wiley   +1 more source

DMBA and Immunosuppression in the Syrian Golden Hamster

open access: yes, 1976
The immunosuppresive effects of topically applied 9, 10 dimethyl 1, 2 benzanthracene (DMBA) were investigated in the Syrian Golden hamster. Tri-weekly doses of DMBA were administered, zith some hamsters receiving both DMBA and X-radiation. DMBA and DMBA-
A. R. Gould
core   +1 more source

Molecular Prerequisites for Diminished Cold Sensitivity in Ground Squirrels and Hamsters

open access: yesCell Reports, 2017
Summary: Thirteen-lined ground squirrels and Syrian hamsters are known for their ability to withstand cold during hibernation. We found that hibernators exhibit cold tolerance even in the active state.
Vanessa Matos-Cruz   +5 more
doaj   +1 more source

Anticancer and Anti‐Inflammatory Potential of Betalains: A Systematic Review on Preclinical Studies

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
Betalains derived from diverse natural sources, including beetroot (Beta vulgaris), Opuntia ficus‐indica, yellow prickly pear, and Atriplex hortensis “rubra” leaf and seed extracts, as well as purified betalains (amaranthin, celosianin, betanin, betaxanthins, and related derivatives), exhibit significant anticancer and anti‐inflammatory activities in ...
Aroob Fatima   +7 more
wiley   +1 more source

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