Results 41 to 50 of about 7,448 (158)

Remodelling of P-bodies and the cytoskeleton by <i>Orthohantavirus puumalaense</i> (Puumala virus). [PDF]

J Gen Virol
Orthohantaviruses are emerging zoonotic pathogens that can cause life-threatening diseases in humans. Their tripartite, negative-sense RNA genome is encapsidated by the viral nucleoprotein, but the subcellular localization and dynamics of these viral RNAs and proteins remain poorly characterized.
Schwarzer-Sperber HS, Petrich A, Schade M, Nilson N, Chibrac-Ahad L, Lehmann MJ, Paulick K, Weiss S, Dluzak T, Bourquain D, Witkowski PT, Krüger DH, Herrmann A, Schwarzer R.   +13 more
europepmc   +5 more sources

First Evidence of Akodon-Borne Orthohantavirus in Northeastern Argentina

EcoHealth, 2021
Orthohantaviruses (genus Orthohantavirus, family Hantaviridae) are the etiologic agents of Hantavirus Pulmonary Syndrome in the Americas. In South America, orthohantaviruses are highly diverse and are hosted by sigmodontine rodents (subfamiliy Sigmodontinae, family Cricetidae), an also diverse group of rodents.
Burgos, Eliana Florencia, Vadell, María Victoria, Bellomo, Carla María, Martinez, Valeria Paula, Salomón, Oscar Daniel, Gomez Villafañe, Isabel Elisa   +5 more
openaire   +3 more sources

Seoul Orthohantavirus in Wild Black Rats, Senegal, 2012–2013 [PDF]

Emerging Infectious Diseases, 2020
Hantaviruses cause hemorrhagic fever in humans worldwide. However, few hantavirus surveillance campaigns occur in Africa. We detected Seoul orthohantavirus in black rats in Senegal, although we did not find serologic evidence of this disease in humans. These findings highlight the need for increased surveillance of hantaviruses in this region.
Diagne, Moussa, Dieng, Idrissa, Granjon, Laurent, Lucaccioni, Héloïse, Sow, Abdourahmane, Ndiaye, Oumar, Faye, Martin, Bâ, Khalilou, Bâ, Yamar, Diallo, Mamoudou, Faye, Oumar, Duplantier, Jean-Marc, Diallo, Mawlouth, Handschumacher, Pascal, Faye, Ousmane, Sall, Amadou   +15 more
openaire   +6 more sources

Infection with New York Orthohantavirus and Associated Respiratory Failure and Multiple Cerebral Complications

Emerging Infectious Diseases, 2019
We report a case of infection with New York orthohantavirus in a woman who showed renal impairment and hemorrhage, complicated by hydrocephalus, in Long Island, New York, USA.
Rajeev Fernando, David Capone, Susan Elrich, Raymond Mantovani, Luther Quarles, Alison D’Amato, Nathan Lowe, Ashwin Malhotra, Teresa Khoo, Sara Zufan, Maria Morales-Betoulle, Shelley M. Brown, Deborah Cannon, James C. Graziano, John D. Klena, Shannon Whitmer, Stuart T. Nichol, Paul Strachan, Bernard C. Camins, Luis A. Marcos   +19 more
doaj   +1 more source

In Vitro Anti-Orthohantavirus Activity of the High-and Low-Molecular-Weight Fractions of Fucoidan from the Brown Alga Fucus evanescens

Marine Drugs, 2021
The Hantaan orthohantavirus (genovariant Amur–AMRV) is a rodent-borne zoonotic virus; it is the causative agent of haemorrhagic fever with renal syndrome in humans.
Natalia V. Krylova, Artem S. Silchenko, Anastasia B. Pott, Svetlana P. Ermakova, Olga V. Iunikhina, Anton B. Rasin, Galina G. Kompanets, Galina N. Likhatskaya, Mikhail Y. Shchelkanov   +8 more
doaj   +1 more source

Andes Virus Genome Mutations That Are Likely Associated with Animal Model Attenuation and Human Person-to-Person Transmission

mSphere, 2023
We performed whole-genome sequencing with bait enrichment techniques to analyze Andes virus (ANDV), a cause of human hantavirus pulmonary syndrome.
Carla M. Bellomo, Daniel O. Alonso, Unai Pérez-Sautu, Karla Prieto, Sebastian Kehl, Rocio M. Coelho, Natalia Periolo, Nicholas Di Paola, Natalia Ferressini-Gerpe, Jens H. Kuhn, Mariano Sanchez-Lockhart, Gustavo Palacios, Valeria P. Martínez   +12 more
doaj   +1 more source

FEATURES OF HEMORRHAGIC FEVER WITH RENAL SYNDROME AMONG CHILDREN POPULATION OF THE PRIMORSKI KRAI

Acta Biomedica Scientifica, 2018
Hemorrhagic fever with renal syndrome is a widespread natural-borne infection of orthohantavirus etiology in the territory of the  Russian Federation.
O. V. Iunikhina, G. G. Kompanets
doaj   +1 more source

Orthohantavirus pulmonary syndrome in Santa Cruz and Tarija, Bolivia, 2018 [PDF]

International Journal of Infectious Diseases, 2020
Orthohantaviruses are still a significant public health threat in endemic countries, with high case fatality rates (CFR). In Bolivia, the reporting of small outbreaks occurred until 2012. The findings of 40 laboratory-confirmed cases diagnosed in two departments are reported herein.This was an observational, retrospective and cross-sectional study ...
Juan Pablo Escalera-Antezana, Roberto Torrez-Fernandez, Dagner Montalvan-Plata, Claudia Marcela Montenegro-Narváez, Jorge Luis Aviles-Sarmiento, Lucia Elena Alvarado-Arnez, D. Katterine Bonilla-Aldana, Alfonso J. Rodríguez-Morales   +7 more
openaire   +3 more sources

Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease

International Journal of Dermatology, EarlyView.
Rodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Giuseppe Gallo, Pietro Quaglino, Simone Ribero   +2 more
wiley   +1 more source

Tropism of Puumala orthohantavirus and Endoparasite Coinfection in the Bank Vole Reservoir

Viruses, 2023
In Europe, most cases of human hantavirus disease are caused by Puumala orthohantavirus (PUUV) transmitted by bank voles (Clethrionomys glareolus, syn. Myodes glareolus), in which PUUV causes inconspicuous infection. Little is known about tropism and endoparasite coinfections in PUUV-infected reservoir and spillover-infected rodents.
Schlohsarczyk, Elfi K., Drewes, Stephan, Koteja, Pawel, Röhrs, Susanne, Ulrich, Rainer G., Teifke, Jens P., Herden, Christiane, Justus Liebig University Giessen   +7 more
openaire   +5 more sources