Results 41 to 50 of about 7,320 (164)

Development of a Comparative European Orthohantavirus Microneutralization Assay With Multi- Species Validation and Evaluation in a Human Diagnostic Cohort

Frontiers in Cellular and Infection Microbiology, 2020
Orthohantaviruses (family Hantaviridae, order Bunyavirales) can cause two serious syndromes in humans: hemorrhagic fever with renal syndrome (HFRS), associated with the Old World orthohantaviruses, and hantavirus cardiopulmonary syndrome (HCPS ...
Tabitha E. Hoornweg, Ilse Zutt, Ankje de Vries, Miriam Maas, Marieke N. Hoogerwerf, Tatjana Avšič-Županc, Miša Korva, Johan H. J. Reimerink, Chantal B. E. M. Reusken   +8 more
doaj   +1 more source

Rodent-Borne Orthohantaviruses in Vietnam, Madagascar and Japan

Viruses, 2021
Hantaviruses are harbored by multiple small mammal species in Asia, Europe, Africa, and the Americas. To ascertain the geographic distribution and virus-host relationships of rodent-borne hantaviruses in Japan, Vietnam, Myanmar, and Madagascar, RNAlater™-
Fuka Kikuchi, Kae Senoo, Satoru Arai, Kimiyuki Tsuchiya, Nguyễn Trường Sơn, Masaharu Motokawa, Marie Claudine Ranorosoa, Saw Bawm, Kyaw San Lin, Hitoshi Suzuki, Akira Unno, Keisuke Nakata, Masashi Harada, Keiko Tanaka-Taya, Shigeru Morikawa, Motoi Suzuki, Tetsuya Mizutani, Richard Yanagihara   +17 more
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Increased Heparanase Levels in Urine during Acute Puumala Orthohantavirus Infection Are Associated with Disease Severity

Viruses, 2022
Old–world orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS), characterized by acute kidney injury (AKI) with transient proteinuria. It seems plausible that proteinuria during acute HFRS is mediated by the disruption of the glomerular ...
Luz E. Cabrera, Constanze Schmotz, Moin A. Saleem, Sanna Lehtonen, Olli Vapalahti, Antti Vaheri, Satu Mäkelä, Jukka Mustonen, Tomas Strandin   +8 more
doaj   +1 more source

Isolation and Genetic Characterization of Puumala Orthohantavirus Strains from France [PDF]

Pathogens, 2021
Puumala orthohantavirus (PUUV) causes a mild form of haemorrhagic fever with renal syndrome (HFRS) called nephropathia epidemica (NE), regularly diagnosed in Europe. France represents the western frontier of the expansion of NE in Europe with two distinct areas: an endemic area (north-eastern France) where PUUV circulates in rodent populations, with ...
Johann Vulin, Séverine Murri, Sarah Madrières, Maxime Galan, Caroline Tatard, Sylvain Piry, Gabriele Vaccari, Claudia D’Agostino, Nathalie Charbonnel, Guillaume Castel, Philippe Marianneau   +10 more
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First Molecular Evidence of Seewis Virus in Croatia

Life, 2023
Orthohantaviruses are mainly carried and transmitted by wild rodents, although during the last decade, they have also been identified in multiple species of shrews and moles.
Petra Svoboda Karić, Barbara Anđelić Dmitrović, Stella Mrmić, Antonia Paić, Linda Bjedov, Zrinka Štritof, Josip Margaletić, Ivan-Christian Kurolt   +7 more
doaj   +1 more source

Data-driven models for replication kinetics of Orthohantavirus infections

Mathematical Biosciences, 2022
The Hantaviridae constitute a family of viruses harbored by mice, rats, shrews, voles, moles and bats. Intriguingly, only viruses harbored by mice and rats may cause disease in humans with up to 40% case fatality rate in the Americas. Transmission of virus from rodents to humans occurs via the respiratory route and results in replication of the virus ...
Adams, Alison, Murphy, Quiyana M., Dougherty, Owen P., Sawyer, Aubrey M., Bai, Fan, Edholm, Christina J., Williams, Evan P., Allen, Linda J. S., Jonsson, Colleen B.   +8 more
openaire   +3 more sources

Longitudinal Assessment of Cytokine Expression and Plasminogen Activation in Hantavirus Cardiopulmonary Syndrome Reveals Immune Regulatory Dysfunction in End-Stage Disease

Viruses, 2021
Pathogenic New World orthohantaviruses cause hantavirus cardiopulmonary syndrome (HCPS), a severe immunopathogenic disease in humans manifested by pulmonary edema and respiratory distress, with case fatality rates approaching 40%.
Peter Simons, Yan Guo, Virginie Bondu, Susan L. Tigert, Michelle Harkins, Samuel Goodfellow, Cana Tompkins, Devon Chabot-Richards, Xuexian O. Yang, Laura Gonzalez Bosc, Steven Bradfute, Daniel A. Lawrence, Tione Buranda   +12 more
doaj   +1 more source

First Evidence of Akodon-Borne Orthohantavirus in Northeastern Argentina

EcoHealth, 2021
Orthohantaviruses (genus Orthohantavirus, family Hantaviridae) are the etiologic agents of Hantavirus Pulmonary Syndrome in the Americas. In South America, orthohantaviruses are highly diverse and are hosted by sigmodontine rodents (subfamiliy Sigmodontinae, family Cricetidae), an also diverse group of rodents.
Burgos, Eliana Florencia, Vadell, María Victoria, Bellomo, Carla María, Martinez, Valeria Paula, Salomón, Oscar Daniel, Gomez Villafañe, Isabel Elisa   +5 more
openaire   +3 more sources

Identification and validation of specific B-cell epitopes of hantaviruses associated to hemorrhagic fever and renal syndrome.

PLoS Neglected Tropical Diseases, 2019
BACKGROUND:Orthohantavirus infection is a neglected global health problem affecting approximately 200,000 people/year, spread by rodent hosts and associated to fatal human diseases, such as hemorrhagic fever with renal syndrome (HFRS) and orthohantavirus
Fernando de Paiva Conte, Bianca Corrêa Tinoco, Thiago Santos Chaves, Renata Carvalho de Oliveira, Janaina Figueira Mansur, Ronaldo Mohana-Borges, Elba Regina Sampaio de Lemos, Patricia Cristina da Costa Neves, Rodrigo Nunes Rodrigues-da-Silva   +8 more
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Orthohantavirus pulmonary syndrome in Santa Cruz and Tarija, Bolivia, 2018 [PDF]

International Journal of Infectious Diseases, 2020
Orthohantaviruses are still a significant public health threat in endemic countries, with high case fatality rates (CFR). In Bolivia, the reporting of small outbreaks occurred until 2012. The findings of 40 laboratory-confirmed cases diagnosed in two departments are reported herein.This was an observational, retrospective and cross-sectional study ...
Juan Pablo Escalera-Antezana, Roberto Torrez-Fernandez, Dagner Montalvan-Plata, Claudia Marcela Montenegro-Narváez, Jorge Luis Aviles-Sarmiento, Lucia Elena Alvarado-Arnez, D. Katterine Bonilla-Aldana, Alfonso J. Rodríguez-Morales   +7 more
openaire   +3 more sources