Results 61 to 70 of about 7,320 (164)

THE DYNAMICS OF ORTHOHANTAVIRUS HANTAAN STRAINS REPLICATION ON THE MODEL OF MOUSE PERITONEAL MACROPHAGES

Acta Biomedica Scientifica, 2018
Orthohantaviruses (Orthohantavirus genus, Hantaviridae family) are the causative agents of a widespread natural focal infection in the  Russian Federation, hemorrhagic fever with renal syndrome (HFRS).
A. B. Pott, O. V. Iunikhina, I. N. Lyapun, G. G. Kompanets   +3 more
doaj   +1 more source

Immunogenic Properties of MVs Containing Structural Hantaviral Proteins: An Original Study

Pharmaceutics, 2022
Hemorrhagic fever with renal syndrome (HFRS) is an emerging infectious disease that remains a global public health threat. The highest incidence rate is among zoonotic disease cases in Russia. Most cases of HFRS are reported in the Volga region of Russia,
Layaly Shkair, Ekaterina Evgenevna Garanina, Ekaterina Vladimirovna Martynova, Alena Igorevna Kolesnikova, Svetlana Sergeevna Arkhipova, Angelina Andreevna Titova, Albert Anatolevich Rizvanov, Svetlana Francevna Khaiboullina   +7 more
doaj   +1 more source

Unraveling the Mechanistic Links Between Species Diversity and Infection Risk From Zoonotic Pathogens With Direct Transmission Among Reservoir Hosts: Rodent‐Orthohantavirus Systems as Models

Ecology and Evolution, Volume 15, Issue 6, June 2025.
In this review, we synthesize mechanistic evidence for diversity‐disease patterns in rodent‐orthohantavirus systems in the Americas, models of directly transmitted disease systems. We found that host regulation has been examined the most while other mechanisms have received less attention. Based on our findings, we propose that for a negative diversity‐
Andreas Eleftheriou, Angela D. Luis
wiley   +1 more source

Spatial and Temporal Evolutionary Patterns in Puumala Orthohantavirus (PUUV) S Segment [PDF]

Pathogens, 2020
The S segment of bank vole (Clethrionomys glareolus)-associated Puumala orthohantavirus (PUUV) contains two overlapping open reading frames coding for the nucleocapsid (N) and a non-structural (NSs) protein. To identify the influence of bank vole population dynamics on PUUV S segment sequence evolution and test for spillover infections in sympatric ...
Florian Binder, René Ryll, Stephan Drewes, Sandra Jagdmann, Daniela Reil, Melanie Hiltbrunner, Ulrike M. Rosenfeld, Christian Imholt, Jens Jacob, Gerald Heckel, Rainer G. Ulrich   +10 more
openaire   +4 more sources

Delayed viral clearance despite high number of activated T cells during the acute phase in Argentinean patients with hantavirus pulmonary syndrome

EBioMedicine, 2022
Summary: Background: The hallmarks of HPS are increase of vascular permeability and endothelial dysfunction. Although an exacerbated immune response is thought to be implicated in pathogenesis, clear evidence is still elusive.
Ayelén Aluminé Iglesias, Natalia Períolo, Carla María Bellomo, Lorena Cecilia Lewis, Camila Paula Olivera, Constanza Rosario Anselmo, Marina García, Rocío María Coelho, Daniel Oscar Alonso, Bonnie Dighero-Kemp, Heema Sharma, Jens H. Kuhn, Nicholas Di Paola, Mariano Sanchez-Lockhart, Gustavo Palacios, Luis Pablo Schierloh, Valeria Paula Martínez   +16 more
doaj   +1 more source

Climate Change‐Driven Heatwaves Pose Lethal Risks to Newborn Forest Bats

Ecology and Evolution, Volume 15, Issue 5, May 2025.
This is the first recorded case of forest bat mortality in temperate regions caused by heatwaves. The study suggests that forest fragmentation exposes bats to lethal thermal peaks, highlighting a previously overlooked impact of climate change on these mammals and potential interactions with forest fragmentation.
Danilo Russo, Anne Mäenurm, Luca Cistrone, Adriano Martinoli, Greta Foiani, Valentina Giongo, Stefania Leopardi   +6 more
wiley   +1 more source

Phylogenetic Characterization of Orthohantavirus dobravaense (Dobrava Virus)

Emerging Infectious Diseases
We report complete coding sequences of Orthohantavirus dobravaense (Dobrava virus) Igneada strains and phylogenetic characterization of all available complete coding sequences. Our analyses suggested separation of host-dependent lineages, followed by geographic clustering.
Erdin, Mert, Polat, Ceylan, Smura, Teemu, Irmak, Sercan, Cetintas, Ortac, Cogal, Muhsin, Colak, Faruk, Karatas, Ahmet, Sozen, Mustafa, Matur, Ferhat, Vapalahti, Olli, Sironen, Tarja, Oktem, Ibrahim Mehmet Ali   +12 more
openaire   +6 more sources

Effect of Land‐Use on Hantavirus Infection Among Introduced and Endemic Small Mammals of Madagascar

Ecology and Evolution, Volume 15, Issue 4, April 2025.
Addressing the risk of Hantavirus spillover from animal reservoirs to humans requires identifying the local reservoirs and the predictors of infection. We screened a collection of 1880 small mammals for Hantavirus RNA from northeastern Madagascar, and specifically investigated the influence of diverse natural or anthropized habitats as well as animal ...
Jérémy Dubrulle, Kayla Kauffman, Voahangy Soarimalala, Toky Randriamoria, Steven M. Goodman, James Herrera, Charles Nunn, Pablo Tortosa   +7 more
wiley   +1 more source

Hantavirus in rodents in the United States: Temporal and spatial trends and report of new hosts

Ecosphere, Volume 16, Issue 3, March 2025.
Abstract In North America, the rodent‐borne hantavirus pulmonary syndrome is predominantly caused by the Sin Nombre virus, typically associated with the deer mouse Peromyscus maniculatus. Utilizing data from the National Ecological Observatory Network (NEON) hantavirus program, we assessed factors that may influence the spatial and temporal ...
Francisca Astorga, Abdelghafar Alkishe, Paanwaris Paansri, Gabriel Mantilla, Luis E. Escobar   +4 more
wiley   +1 more source

Puumala Orthohantavirus Reassortant Genome Variants Likely Emerging in the Watershed Forests

International Journal of Molecular Sciences, 2023
Hemorrhagic fever with renal syndrome (HFRS) remains a prevalent zoonosis in the Republic of Tatarstan (RT), Russian Federation. Puumala orthohantavirus (PUUV), carried by bank voles (Myodes glareolus), is the principal zoonotic pathogen of HFRS in the RT.
Emmanuel Kabwe, Anton F. Shamsutdinov, Setora Suleimanova, Ekaterina V. Martynova, Ruzilya K. Ismagilova, Venera G. Shakirova, Tatiana A. Savitskaya, Guzel S. Isaeva, Albert A. Rizvanov, Svetlana F. Khaiboullina, Sergey P. Morzunov, Yuriy N. Davidyuk   +11 more
openaire   +2 more sources