Results 61 to 70 of about 7,672 (161)

The Changing Landscape of Hantavirus Infections: A Narrative Review of Epidemiology, Pathogenesis, and Countermeasures

Reviews in Medical Virology, Volume 36, Issue 5, September 2026.
ABSTRACT Hantaviruses are emerging zoonotic pathogens of increasing global public health significance. Their epidemiological landscape is rapidly changing due to ecological disruption, climate variability, urbanisation, and evolving human–animal interfaces.
Francesco De Maria, Francesco Branda, Giancarlo Ceccarelli, Fabio Scarpa, Massimo Ciccozzi, Alessandro Russo   +5 more
wiley   +1 more source

A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies.

PLoS Pathogens
Orthohantaviruses are emerging zoonotic viruses that can infect humans via the respiratory tract. There is an unmet need for an in vivo model to study infection of different orthohantaviruses in physiologically relevant tissue and to assess the efficacy ...
Melanie Rissmann, Danny Noack, Thomas M Spliethof, Vincent P Vaes, Rianne Stam, Peter van Run, Jordan J Clark, Georges M G M Verjans, Bart L Haagmans, Florian Krammer, Marion P G Koopmans, Judith M A van den Brand, Barry Rockx   +12 more
doaj   +1 more source

Use of a diagnostic Puumala virus real-time RT-PCR in an orthohantavirus endemic region in the Netherlands

Microbiology Spectrum
Laboratory diagnosis of orthohantavirus infection is primarily based on serology. However, for a confirmed serological diagnosis, evaluation of a follow-up serum sample is essential, which is time consuming and causes delay.
Felix Geeraedts, Mariska Wevers, Froukje Bosma, Maria de Boer, J. N. Brinkman, Corine Delsing, Corine GeurtsvanKessel, Barry Rockx, Adri van der Zanden, Gozewijn D. Laverman   +9 more
doaj   +1 more source

Genomic Epidemiology and Active Surveillance to Investigate Outbreaks of Hantaviruses

Frontiers in Cellular and Infection Microbiology, 2021
Emerging and re-emerging RNA viruses pose significant public health, economic, and societal burdens. Hantaviruses (genus Orthohantavirus, family Hantaviridae, order Bunyavirales) are enveloped, negative-sense, single-stranded, tripartite RNA viruses that
Won-Keun Kim, Won-Keun Kim, Seungchan Cho, Seung-Ho Lee, Jin Sun No, Geum-Young Lee, Kyungmin Park, Kyungmin Park, Daesang Lee, Seong Tae Jeong, Jin-Won Song, Jin-Won Song   +11 more
doaj   +1 more source

Remodelling of P-bodies and the cytoskeleton by <i>Orthohantavirus puumalaense</i> (Puumala virus). [PDF]

J Gen Virol
Orthohantaviruses are emerging zoonotic pathogens that can cause life-threatening diseases in humans. Their tripartite, negative-sense RNA genome is encapsidated by the viral nucleoprotein, but the subcellular localization and dynamics of these viral RNAs and proteins remain poorly characterized.
Schwarzer-Sperber HS, Petrich A, Schade M, Nilson N, Chibrac-Ahad L, Lehmann MJ, Paulick K, Weiss S, Dluzak T, Bourquain D, Witkowski PT, Krüger DH, Herrmann A, Schwarzer R.   +13 more
europepmc   +5 more sources

Temporal Dynamics of Viremia in Hemorrhagic Fever With Renal Syndrome Patients

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT The pathogenesis of hemorrhagic fever with renal syndrome (HFRS) remains incompletely understood. Currently, the clinical diagnosis of HFRS primarily relies on epidemiological history and clinical presentation, while the confirmation of HFRS depends mainly on the detection of hemorrhagic fever antibodies.
ShuWei Ma, JiaYi Zhan, Chao Fan, XuYang Zheng, Hong Du, LiMei Wang, Hong Jiang   +6 more
wiley   +1 more source

Community Assembly Reveals How Environmental Controls Over Rodent Competition Drive Deer Mouse Density and Hantavirus Infection

Ecology Letters, Volume 29, Issue 4, April 2026.
We examined how community assembly processes shape Sin Nombre hantavirus (SNV) dynamics in rodent communities across the southwestern United States. Environmental factors structured community composition, which regulated deer mouse abundance and SNV infection, rather than diversity alone.
Angela D. Luis, Dean E. Pearson
wiley   +1 more source

Immunogenic Properties of MVs Containing Structural Hantaviral Proteins: An Original Study

Pharmaceutics, 2022
Hemorrhagic fever with renal syndrome (HFRS) is an emerging infectious disease that remains a global public health threat. The highest incidence rate is among zoonotic disease cases in Russia. Most cases of HFRS are reported in the Volga region of Russia,
Layaly Shkair, Ekaterina Evgenevna Garanina, Ekaterina Vladimirovna Martynova, Alena Igorevna Kolesnikova, Svetlana Sergeevna Arkhipova, Angelina Andreevna Titova, Albert Anatolevich Rizvanov, Svetlana Francevna Khaiboullina   +7 more
doaj   +1 more source

Surveillance of Zoonotic Pathogens in Small Mammals Across Forests With Different Levels of Anthropization in Eastern France

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The emergence of infectious diseases associated with land‐use changes is well‐documented. However, the presence and dynamics of zoonotic pathogens in small mammals within European forests, whether from rural development or urban greening, remain underexplored.
Marie Bouilloud, Maxime Galan, Anaïs Bordes, Caroline Tatard, Philippe Gauthier, Julien Pradel, Guillaume Castel, Hussein Alburkat, Lara Dutra, Tarja Sironen, Clémence Galon, Sara Moutailler, Zorée Djelouadji, Benjamin Roche, Nathalie Charbonnel, Javier Millán   +15 more
wiley   +1 more source

Phylogenetic Characterization of Orthohantavirus dobravaense (Dobrava Virus)

Emerging Infectious Diseases
We report complete coding sequences of Orthohantavirus dobravaense (Dobrava virus) Igneada strains and phylogenetic characterization of all available complete coding sequences. Our analyses suggested separation of host-dependent lineages, followed by geographic clustering.
Oktem, Ibrahim Mehmet Ali, Sironen, Tarja, Vapalahti, Olli, Matur, Ferhat, Sozen, Mustafa, Karatas, Ahmet, Colak, Faruk, Cogal, Muhsin, Cetintas, Ortac, Irmak, Sercan, Smura, Teemu, Polat, CEYLAN, Erdin, Mert   +12 more
openaire   +7 more sources