Results 81 to 90 of about 7,672 (161)

Hantavirus in rodents in the United States: Temporal and spatial trends and report of new hosts

open access: yesEcosphere, Volume 16, Issue 3, March 2025.
Abstract In North America, the rodent‐borne hantavirus pulmonary syndrome is predominantly caused by the Sin Nombre virus, typically associated with the deer mouse Peromyscus maniculatus. Utilizing data from the National Ecological Observatory Network (NEON) hantavirus program, we assessed factors that may influence the spatial and temporal ...
Francisca Astorga   +4 more
wiley   +1 more source

Report of a novel pathogenic orthohantavirus in Tucuman, Argentina

open access: yesRevista Argentina de Microbiología
The confirmation of two cases of hantavirus pulmonary syndrome (HPS) in the city of San Miguel de Tucuman, province of Tucuman, is described in the present study. In 2021, the diagnosis of two patients with HPS with no history of travel outside the province was confirmed. The infection was determined by serology in both cases. Case 1 had an unfavorable
Julia Brignone   +11 more
openaire   +2 more sources

Interactions Between Hantavirus Nucleoprotein and Glycoproteins: A Quantitative Fluorescence Microscopy Study

open access: yesViruses
Orthohantaviruses are tri-segmented negative-sense RNA viruses that can cause severe pathologies in humans. Currently, limited information exists on the molecular interactions driving orthohantavirus assembly in infected cells.
Amit Koikkarah Aji   +2 more
doaj   +1 more source

Hantaan virus glycoprotein Gc induces NEDD4‐dependent PTEN ubiquitination and degradation to escape the restriction of autophagosomes and facilitate viral propagation

open access: yesThe FASEB Journal, Volume 39, Issue 1, 15 January 2025.
The proposed model of HTNV induced PTEN degradation and PTEN‐regulated autophagy in progeny virus production: In HTNV‐infected HK‐2 cells, the viral Gc glycoprotein specifically promotes NEDD4 mediated ubiquitination and degradation of PTEN. Disruption of PTEN expression prevents autophagosome formation and increases HTNV production, whereas ...
Shuang Lu   +16 more
wiley   +1 more source

Unveiling Common Bean (Phaseolus vulgaris L) RNA‐ and DNA‐Based Virome in Western Kenya: Insights From Metatranscriptomic and Metagenomic Signatures

open access: yesAdvances in Virology, Volume 2025, Issue 1, 2025.
Common bean (Phaseolus vulgaris L) is Kenya’s second most important agricultural product after maize, serving as a vital source of protein for many rural families in Western Kenya. However, viral diseases caused by RNA and DNA viruses greatly impair bean productivity, often leading to yield losses of up to 100%, thus contributing to food insecurity ...
Aggrey Keya Osogo   +4 more
wiley   +1 more source

Serum Concentrations of TIM-3, LAG-3, and PD-1 in Patients with Hemorrhagic Fever with Renal Syndrome

open access: yesLife
Hemorrhagic fever with renal syndrome (HFRS) is a rodent-borne disease widespread in Europe and Asia. HFRS is caused by negative-sensed single-stranded RNA orthohantaviruses transmitted to humans through inhaling aerosolized excreta of infected rodents ...
Željka Mačak Šafranko   +6 more
doaj   +1 more source

Phylogeographic diversity and hybrid zone of Hantaan orthohantavirus collected in Gangwon Province, Republic of Korea.

open access: yesPLoS Neglected Tropical Diseases, 2020
BackgroundHantaan orthohantavirus (Hantaan virus, HTNV), harbored by Apodemus agrarius (the striped field mouse), causes hemorrhagic fever with renal syndrome (HFRS) in humans. Viral genome-based surveillance at new expansion sites to identify HFRS risks
Geum-Young Lee   +13 more
doaj   +1 more source

Wildlife Pathogens and Zoonotic Disease Risk Assessment in Vietnam: A Wildlife Trade Hotspot

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Vietnam is a wildlife trade hotspot presenting multiple high‐risk interfaces for pathogen spillover from wildlife to humans. However, the zoonotic disease risk remains poorly characterized in the country and needs to be assessed to better inform policy dialog and legislative reforms.
Alice Latinne   +2 more
wiley   +1 more source

Evaluation of a Luminex‐Based Multiplex Immunoassay of Hemorrhagic Fever Viruses in Senegal

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Given the growing threat posed by viral hemorrhagic fevers, the development of surveillance tools is crucial to provide accurate and rapid solutions. Public health response involves risk assessment as well as effective and sustainable surveillance to ensure downstream communication and preparedness. A serological approach that offers high precision and
Safietou Sankhe   +17 more
wiley   +1 more source

Puumala Hantavirus Genotypes in Humans, France, 2012–2016

open access: yesEmerging Infectious Diseases, 2019
The analysis of the nucleoprotein gene of 77 Puumala hantavirus strains detected in human samples in France during 2012–2016 showed that all belonged to the Central European lineage.
Jean-Marc Reynes   +3 more
doaj   +1 more source

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