Results 71 to 80 of about 7,672 (161)
EBioMedicine, 2022 Summary: Background: The hallmarks of HPS are increase of vascular permeability and endothelial dysfunction. Although an exacerbated immune response is thought to be implicated in pathogenesis, clear evidence is still elusive.
Ayelén Aluminé Iglesias +16 more
doaj +1 more source
Acta Biomedica Scientifica, 2018 Orthohantaviruses (Orthohantavirus genus, Hantaviridae family) are the causative agents of a widespread natural focal infection in the Russian Federation, hemorrhagic fever with renal syndrome (HFRS).
A. B. Pott +3 more
doaj +1 more source
Journal of Medical Virology, Volume 97, Issue 7, July 2025.ABSTRACT Orthohantavirus puumalaense causes hemorrhagic fever with renal syndrome in Europe, with Puumala virus (PUUV) as its primary representative. Muju virus (MUJV), harbored by Craseomys regulus, an Arvicolinae rodent species endemic to the Republic of Korea (ROK), is also a genotype of O. puumalaense.
Kyungmin Park +12 more
wiley +1 more source
Dissection of the NKG2C NK cell response against Puumala Orthohantavirus
PLOS Neglected Tropical Diseases, 2021 Background Infections with the Puumala orthohantavirus (PUUV) in humans may cause hemorrhagic fever with renal syndrome (HFRS), known as nephropathia epidemica (NE), which is associated with acute renal failure in severe cases. In response to PUUV-infections, a subset of potent antiviral NKG2C+ NK cells expand, whose role in virus defence and ...
Hannes Vietzen +3 more
openaire +4 more sources
Ecology and Evolution, Volume 15, Issue 6, June 2025.In this review, we synthesize mechanistic evidence for diversity‐disease patterns in rodent‐orthohantavirus systems in the Americas, models of directly transmitted disease systems. We found that host regulation has been examined the most while other mechanisms have received less attention. Based on our findings, we propose that for a negative diversity‐
Andreas Eleftheriou, Angela D. Luis
wiley +1 more source
Quantification and kinetics of viral RNA transcripts produced in Orthohantavirus infected cells
Virology Journal, 2018 Background Rodent borne viruses of the Orthohantavirus genus cause hemorrhagic fever with renal syndrome among people in Eurasia, and hantavirus cardiopulmonary syndrome in the Americas.
Julia Wigren Byström +6 more
doaj +1 more source
Climate Change‐Driven Heatwaves Pose Lethal Risks to Newborn Forest Bats
Ecology and Evolution, Volume 15, Issue 5, May 2025.This is the first recorded case of forest bat mortality in temperate regions caused by heatwaves. The study suggests that forest fragmentation exposes bats to lethal thermal peaks, highlighting a previously overlooked impact of climate change on these mammals and potential interactions with forest fragmentation.
Danilo Russo +6 more
wiley +1 more source
Genetic diversity and phylogeography of Jeju Orthohantavirus (Hantaviridae) in the Republic of Korea
Virology, 2020 Orthohantaviruses are negative-sense, single-stranded RNA viruses harbored by rodents, shrews, moles, and bats. Of the shrew-borne orthohantaviruses in the Republic of Korea (ROK), Jeju orthohantavirus (Jeju virus, JJUV) was found on Jeju Island. This small-scale epidemiologic survey investigated the geographic distribution and molecular phylogeny of ...
Seung-Ho, Lee +11 more
openaire +2 more sources
Effect of Land‐Use on Hantavirus Infection Among Introduced and Endemic Small Mammals of Madagascar
Ecology and Evolution, Volume 15, Issue 4, April 2025.Addressing the risk of Hantavirus spillover from animal reservoirs to humans requires identifying the local reservoirs and the predictors of infection. We screened a collection of 1880 small mammals for Hantavirus RNA from northeastern Madagascar, and specifically investigated the influence of diverse natural or anthropized habitats as well as animal ...
Jérémy Dubrulle +7 more
wiley +1 more source
Virus- and cell type-specific effects in orthohantavirus infection
Virus Research, 2019 Orthohantaviruses Hantaan (HTNV) and Puumala (PUUV) virus cause hemorrhagic fever with renal syndrome (HFRS), that is characterized by acute renal failure with often massive proteinuria and by morphological changes of the tubular and glomerular apparatus. Orthohantaviral N protein is found in renal cells and plays a key role in replication.
Stefan Hägele +5 more
openaire +2 more sources