Results 71 to 80 of about 7,320 (164)
PLoS Neglected Tropical Diseases, 2020 BackgroundHantaan orthohantavirus (Hantaan virus, HTNV), harbored by Apodemus agrarius (the striped field mouse), causes hemorrhagic fever with renal syndrome (HFRS) in humans. Viral genome-based surveillance at new expansion sites to identify HFRS risks
Geum-Young Lee +13 more
doaj +1 more source
Puumala Hantavirus Infections Show Extensive Variation in Clinical Outcome
Viruses, 2023 The clinical outcome of Puumala hantavirus (PUUV) infection shows extensive variation, ranging from inapparent subclinical infection (70–80%) to severe hemorrhagic fever with renal syndrome (HFRS), with about 0.1% of cases being fatal.
Antti Vaheri +10 more
doaj +1 more source
The FASEB Journal, Volume 39, Issue 1, 15 January 2025.The proposed model of HTNV induced PTEN degradation and PTEN‐regulated autophagy in progeny virus production: In HTNV‐infected HK‐2 cells, the viral Gc glycoprotein specifically promotes NEDD4 mediated ubiquitination and degradation of PTEN. Disruption of PTEN expression prevents autophagosome formation and increases HTNV production, whereas ...
Shuang Lu +16 more
wiley +1 more source
Virus- and cell type-specific effects in orthohantavirus infection
Virus Research, 2019 Orthohantaviruses Hantaan (HTNV) and Puumala (PUUV) virus cause hemorrhagic fever with renal syndrome (HFRS), that is characterized by acute renal failure with often massive proteinuria and by morphological changes of the tubular and glomerular apparatus. Orthohantaviral N protein is found in renal cells and plays a key role in replication.
Stefan Hägele +5 more
openaire +2 more sources
Advances in Virology, Volume 2025, Issue 1, 2025.Common bean (Phaseolus vulgaris L) is Kenya’s second most important agricultural product after maize, serving as a vital source of protein for many rural families in Western Kenya. However, viral diseases caused by RNA and DNA viruses greatly impair bean productivity, often leading to yield losses of up to 100%, thus contributing to food insecurity ...
Aggrey Keya Osogo +4 more
wiley +1 more source
Fundamental and applied research for key propriety areas of bioecology and biotechnology, 2023 В статье проведён сравнительный и филогенетический анализ нуклеотидных последовательностей S- и M-сегментов штаммов Puumala orthohantavirus из Бавлинского района Республики Татарстан. Установлено, что исследованные штаммы не имеют близкого родства с другими штаммами из Закамья Татарстана и, вероятно, могут относиться к отдельной группе штаммов ...
Timur R. Nasyrov; Kazan Federal University +1 more
openaire +2 more sources
Wildlife Pathogens and Zoonotic Disease Risk Assessment in Vietnam: A Wildlife Trade Hotspot
Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.Vietnam is a wildlife trade hotspot presenting multiple high‐risk interfaces for pathogen spillover from wildlife to humans. However, the zoonotic disease risk remains poorly characterized in the country and needs to be assessed to better inform policy dialog and legislative reforms.
Alice Latinne +2 more
wiley +1 more source
Quantification and kinetics of viral RNA transcripts produced in Orthohantavirus infected cells
Virology Journal, 2018 Background Rodent borne viruses of the Orthohantavirus genus cause hemorrhagic fever with renal syndrome among people in Eurasia, and hantavirus cardiopulmonary syndrome in the Americas.
Julia Wigren Byström +6 more
doaj +1 more source
Evaluation of a Luminex‐Based Multiplex Immunoassay of Hemorrhagic Fever Viruses in Senegal
Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.Given the growing threat posed by viral hemorrhagic fevers, the development of surveillance tools is crucial to provide accurate and rapid solutions. Public health response involves risk assessment as well as effective and sustainable surveillance to ensure downstream communication and preparedness. A serological approach that offers high precision and
Safietou Sankhe +17 more
wiley +1 more source
Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.Ticks serve as critical viral vectors, and border regions, acting as convergence zones of complex ecosystems, provide diverse habitats for ticks and their hosts, thereby underscoring the need to investigate the tick‐borne virome composition in such areas. In this study, metatranscriptomic analysis of five tick species, namely Haemaphysalis longicornis,
Zhe Liu +15 more
wiley +1 more source