Results 121 to 130 of about 71,928 (261)

Effect of Small Molecules on Blastocyst Development and Outgrowth Establishment of Bovine Haploid Parthenogenetic Embryos. [PDF]

Animals (Basel)
Aguila L, Castillo R, Pérez-García F, Treulen F, Valencia C, Perecin F, Smith LC, Arias ME, Felmer R.   +8 more
europepmc   +1 more source

Reductive Methylation: An Alternative to Lysine → Arginine Mutagenesis

Journal of Peptide Science, Volume 32, Issue 7, July 2026.
Replacing lysine with arginine, the standard genetic approach to eliminate amine reactivity, alters physicochemical properties and leaves the N terminus unprotected. Here, reductive methylation is characterized as a conservative chemical alternative. Complete dimethylation of human ribonucleases preserves thermostability, protein–protein interaction ...
Oscar J. Molina, Clair S. Gutierrez, Jinyi Yang, Evans C. Wralstad, Ronald T. Raines   +4 more
wiley   +1 more source

Targeted CENH3 protein depletion in egg cells enables highly efficient haploid induction. [PDF]

Plant Commun
Somasundaram S, Yaşar S, Fuchs J, Cuacos M, Claassen J, Weiss O, Kochevenko A, Lamb JC, Li T, Capdeville N, Puchta H, Houben A.   +11 more
europepmc   +1 more source

De Novo Genome Assemblies of Four Rainbow Trout Genetic Lines Reveal Structural Variants in Pursuit of a Pangenome Reference

Molecular Ecology Resources, Volume 26, Issue 5, July 2026.
ABSTRACT Rainbow trout (Oncorhynchus mykiss) exhibit extensive genomic diversity shaped by domestication, life history and geographic origin. To advance the development of a comprehensive pangenome reference, we present new de novo genome assemblies of two genetically and ecologically distinct lines: Whale Rock (WR; wild, landlocked, Central California)
Ali Ali, Geoffrey C. Waldbieser, Ramey C. Youngblood, Paul A. Wheeler, Brian E. Scheffler, Stuart Willis, Shawn R. Narum, Gary H. Thorgaard, Mohamed Salem, Yniv Palti   +9 more
wiley   +1 more source

Mitochondrial metabolic imbalance drives diploidization in mouse haploid embryonic stem cells via NADPH overload. [PDF]

Nat Commun
Di Minin G, Rüegg AB, Halter K, Fuhrer T, Kleele T, Zamboni N, Wutz A.   +6 more
europepmc   +1 more source

Microtubule Inner Protein CFAP77 Contributes to Sperm Motility and Male Fertility in Mice

Andrology, Volume 14, Issue 5, Page 1240-1248, July 2026.
ABSTRACT Background Sperm motility is essential for male fertility, and its regulation is dependent on the structural integrity of the axoneme. The axoneme consists of a conserved “9+2” microtubule arrangement and is supported by microtubule inner proteins. However, the functional significance of many microtubule inner proteins remains unclear.
Haoting Wang, Anh Hoang Pham, Mengjiao Luo, Masahito Ikawa, Haruhiko Miyata   +4 more
wiley   +1 more source

Aneuploidy promotes transient stress adaptation and metabolic flexibility in the human fungal pathogen Aspergillus fumigatus. [PDF]

Curr Biol
Lehmann AE, Aguilar Ramírez E, Keller NP, Heitman J.   +3 more
europepmc   +1 more source

Interaction Between Rec8 and Mis4 Is Required for Axis‐Loop Chromatin Formation and Homologous Chromosome Recombination During Meiosis

Genes to Cells, Volume 31, Issue 4, July 2026.
We identified a Mis4 cohesin loader mutant that is specifically defective in chromatin axis formation and homologous recombination while retaining normal sister chromatid cohesion. The mis4‐LR mutant, carrying the L1150S and R1159G amino acid substitutions, exhibited reduced interaction between Mis4 and Rec8, suggesting a meiosis‐specific role for the ...
Takeshi Sakuno, Yasuto Murayama, Tokuko Haraguchi, Yasushi Hiraoka   +3 more
wiley   +1 more source

Chromosomal rearrangements: tempo and mode of karyotype evolution in Scarabaeoidea. [PDF]

J Evol Biol
Chien S, Blackmon H.
europepmc   +1 more source

Progress and Challenges in Phylogenomics and Genomics of Lophotrochozoa/Spiralia

Zoologica Scripta, Volume 55, Issue 4, Page 521-544, July 2026.
ABSTRACT Lophotrochozoa is one of the three major bilaterian groups comprising more than half of the bilaterian phyla. Lophotrochozoa includes among others Mollusca, Annelida, Platyhelminthes and Rotifera. Despite representing such a large proportion of animal diversity, they are historically understudied and genomic resources have been scarce. However,
Torsten H. Struck
wiley   +1 more source