Results 181 to 190 of about 275,736 (271)

Expanding Phenotype of GINS1 Deficiency: A Case Report and Review of the Literature

Clinical Genetics, EarlyView.
The authors present a novel case and review of individuals with GINS1 deficiency, causing severe growth restriction and combined immunodeficiency. Only the ninth case of this ultrarare disorder, it highlights the role of these variants in disease, glaucoma as a feature, and the possibility of immunodeficiency without infections in affected individuals.
Michael P. Mackley, Rae Brager, Hannah Geddie, Vicky Breakey, Rebecca Hough, Dimitrios J. Stavropoulos, Vanda McNiven   +6 more
wiley   +1 more source

High-resolution quantitative trait loci mapping and pyramiding effects of candidate genes for plant height in soybean. [PDF]

Plant Genome
Sha D, Zhang Z, Gu Y, Zhang S, Khattak AN, Liu Y, Ma C, Hu M, Niu J, Yu L, Zhang S, Iqbal A, Muhammad A, Li J, Sun J, Guan R, Li B.   +16 more
europepmc   +1 more source

Gene flow among Pacific harbor seals in Northern California [PDF]

, 2009
Conrad, Michele Maria
core   +1 more source

Clinical‐Grade Human Induced Pluripotent Stem Cell‐Derived Neural Precursor Cells Restore Motor Function and Preserve Striatal Integrity in a Quinolinic Acid‐Lesioned Rat Model of Huntington's Disease

Cell Proliferation, EarlyView.
Clinical‐grade HLA‐homozygous iPSC‐derived neural precursor cells restore motor function, rebuild striatal circuitry and reduce neuroinflammation in QA‐lesioned rats. These findings demonstrate robust neuronal replacement and microenvironment modulation, supporting their potential as a regenerative therapy for Huntington's disease.
Hyeonjoong Jeon, Il‐Shin Lee, Sanghun Lee, Hyo Chang Park, Beomsoo Kim, Hyun Sook Kim, Jihwan Song   +6 more
wiley   +1 more source

Exploring the potential of naked barley to manage deoxynivalenol accumulation from Fusarium head blight. [PDF]

Theor Appl Genet
Ige AD, Hawkins J, Dong Y, Meints B, Smith K.   +4 more
europepmc   +1 more source

Distinct Tryptase Gene Copy Number Variations Correlate With Tryptase Levels in a Population‐Based Cohort

Allergy, EarlyView.
Yannick Chantran, Simone Choi, Céline Roda, Stéphane Barete, Pierre Hirsch, Olivier Hermine, Laura Polivka, Julien Rossignol, Michel Arock, Fanny Rancière, Isabelle Momas   +10 more
wiley   +1 more source

An international consensus on screening and monitoring early‐stage type 1 diabetes: A roadmap to European implementation

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Type 1 diabetes (T1D) is a chronic autoimmune disease that results in loss of insulin‐secreting pancreatic β‐cells in the islets of Langerhans. A diagnosis of T1D is typically associated with children and adolescents, yet half of all diagnoses of T1D are made in adults.
Sufyan Hussain, Timothy Tree, Chantal Mathieu, Tomasz Klupa, Anna‐Kaisa Tuomaala, Maartje de Wit, Olga Kordonouri, Katarina Braune, Jaivir Pall, Luis Castano, Rachel E. J. Besser, Júlia Galhardo, Francesca Ulivi, Emanuele Bosi, Uroš Bogdanovic, Coralie Alabert, Tadej Battelino   +16 more
wiley   +1 more source

Haplotype-resolved and near telomere-to-telomere assembly of the autotetraploid potato genome. [PDF]

Genome Biol
Xiao PX, Tan L, Dong J, Huang J, Huang Y, He JB, Su H, Song B, Jiao WB.   +8 more
europepmc   +1 more source

Teplizumab in Stage 2 Type 1 Diabetes: Clinical Practice Experience on Feasibility in 3 Adult Patients

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To describe the first Italian experience with teplizumab administered under a compassionate use programme for adults with Stage 2 type 1 diabetes (T1D), and to evaluate its feasibility, safety and early metabolic outcomes in a real‐life clinical setting outside formal clinical trials.
V. Guarnotta, F. Pantò, E. Vigneri, G. Piombo, M. I. Mineo, L. Tomasello, G. Arnaldi   +6 more
wiley   +1 more source

Genome-wide exploration of bacterial leaf blight resistance and fine mapping of major resistance gene (Bb13) in upland cotton (Gossypium hirsutum L.). [PDF]

Plant Genome
Gandhadmath SS, Bourland FM, Gowda SA, Shrestha N, Jones DC, Bissonnette K, Kuraparthy V.   +6 more
europepmc   +1 more source