Results 231 to 240 of about 290,368 (328)

The S 15 Self-Incompatibility Haplotype in Brassica Oleracea Includes Three S Gene Family Members Expressed in Stigmas [PDF]

open access: green, 1999
Didier Cabrillac   +7 more
openalex   +1 more source

RDAforest: Identifying Environmental Drivers of Polygenic Adaptation

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT Identifying environmental gradients driving genetic adaptation is one of the major goals of ecological genomics. We present RDAforest, a methodology that leverages the predominantly polygenic nature of adaptation and harnesses the versatility of random forest regression to solve this problem.
Mikhail V. Matz, Kristina L. Black
wiley   +1 more source

Methods for multiancestry genome‐wide association study meta‐analysis

open access: yesAnnals of Human Genetics, EarlyView.
Abstract Genome‐wide association studies (GWAS) have significantly enhanced our understanding of the genetic basis of complex diseases. Despite the technological advancements, gaps in our understanding remain, partly due to small effect sizes and inadequate coverage of genetic variation.
Chuan Fu Yap, Andrew P. Morris
wiley   +1 more source

The molecular basis of lactase persistence: Linking genetics and epigenetics

open access: yesAnnals of Human Genetics, EarlyView.
Abstract Lactase persistence (LP) — the genetic trait that determines the continued expression of the enzyme lactase into adulthood — has undergone recent, rapid positive selection since the advent of animal domestication and dairying in some human populations.
Céleste E. Cohen   +2 more
wiley   +1 more source

Genetic Determinants of the Familial Hypercholesterolaemia Phenotype

open access: yesAnnals of Human Genetics, EarlyView.
ABSTRACT Individuals with familial hypercholesterolaemia (FH) have severely elevated plasma concentrations of low‐density lipoprotein cholesterol (LDL‐C) from birth and as a consequence have an elevated morbidity and mortality due to the development of coronary heart disease (CHD).
Steve Eric Humphries, Marta Futema
wiley   +1 more source

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