Results 21 to 30 of about 295,678 (328)
The dynamics of alternative pathways to compensatory substitution [PDF]
, 2013 The role of epistatic interactions among loci is a central question in evolutionary biology and is increasingly relevant in the genomic age. While the population genetics of compensatory substitution have received considerable attention, most studies ...
Nasrallah, Chris A.
core +2 more sources
Long-range, high-throughput haplotype determination via haplotype-fusion PCR and ligation haplotyping [PDF]
Nucleic Acids Research, 2008 Ligation Haplotyping is a robust, novel method for experimental determination of haplotypes over long distances, which can be applied to assaying both sequence and structural variation. The simplicity and efficacy of the method for genotyping large chromosomal rearrangements and haplotyping SNPs over long distances make it a valuable and powerful ...
Daniel J. Turner +2 more
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Frontiers in Genetics, 2021 Detection of CNVs (copy number variants) and ROH (runs of homozygosity) from SNP (single nucleotide polymorphism) genotyping data is often required in genomic studies.
Jinghang Zhou +6 more
doaj +1 more source
Association of polymorphisms of the ADIPOQ, ADIPOR1 and ADIPOR2 genes with type 2 diabetes mellitus
Сахарный диабет, 2015 The study of hereditary predisposition to multifactorial diseases is essential for diagnosis and selection of the optimal treatment. The study of polymorphisms of candidate genes whose products are involved in the pathogenesis of multifactorial diseases ...
Dmitry Sergeevich Khodyrev +9 more
doaj +1 more source
Persian Journal of Acarology, 2019 A molecular characterization based on mitochondrial cytochrome oxidase subunit I gene was used to genotype central-southern Iranian populations of Varroa destructor for the first time.
Zahra Hajializadeh +3 more
doaj +1 more source
Of Genes, Blocks, and Haplotypes [PDF]
Biology of Blood and Marrow Transplantation, 2012 indicate normal function. Today, functional assays such as with tetramer staining, intracellular cytokine staining, and degranulation assays, are becoming more readily available and allow us to functionally interrogate lymphocyte subpopulations. These assessments, if validated as predictors of infection and relapse, will not only help elucidate the ...
openaire +3 more sources
Pure Parsimony Xor Haplotyping [PDF]
IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2009 The haplotype resolution from xor-genotype data has been recently formulated as a new model for genetic studies. The xor-genotype data is a cheaply obtainable type of data distinguishing heterozygous from homozygous sites without identifying the homozygous alleles.
BONIZZONI, PAOLA +4 more
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Introgression Breeding in Barley: Perspectives and Case Studies
Frontiers in Plant Science, 2020 Changing production scenarios resulting from unstable climatic conditions are challenging crop improvement efforts. A deeper and more practical understanding of plant genetic resources is necessary if these assets are to be used effectively in developing
Javier Hernandez +2 more
doaj +1 more source
Diploid Alignments and Haplotyping [PDF]
, 2015 Sequence alignments have been studied for decades under the simplified model of a consensus sequence representing a chromosome. A natural question is if there is some more accurate notion of alignment for diploid (and in general, polyploid) organisms.
Valenzuela Daniel, Mäkinen Veli
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Frontiers in Pharmacology, 2023 Arylamine N-acetyltransferase 2 (NAT2) is a phase II metabolic enzyme, best known for metabolism of aromatic amines and hydrazines. Genetic variants occurring in the NAT2 coding region have been well-defined and are known to affect the enzyme activity or
Kyung U. Hong +2 more
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