Results 21 to 30 of about 275,736 (271)

A genome-wide combinatorial strategy dissects complex genetic architecture of seed coat colour in chickpea

Frontiers in Plant Science, 2015
The study identified 9045 high-quality SNPs employing both genome-wide GBS- and candidate gene-based SNP genotyping assays in 172, including 93 cultivated (desi and kabuli) and 79 wild chickpea accessions.
Deepak eBajaj, Shouvik eDas, Hari Deo eUpadhyaya, Rajeev eRanjan, Rajeev eRanjan, SAURABH eBADONI, Vinod eKumar, Shailesh eTripathi, CL Laxmipathi Gowda, Shivali eSharma, Sube eSingh, Akhilesh eTyagi, SWARUP KUMAR PARIDA   +12 more
doaj   +1 more source

Ultraaccurate genome sequencing and haplotyping of single human cells. [PDF]

, 2017
Accurate detection of variants and long-range haplotypes in genomes of single human cells remains very challenging. Common approaches require extensive in vitro amplification of genomes of individual cells using DNA polymerases and high-throughput short ...
Bafna, Vineet, Bansal, Vikas, Chu, Wai Keung, Edge, Peter, Huang, Xiaohua, Lee, Ho Suk, Zhang, Kun   +6 more
core   +1 more source

HandyCNV: Standardized Summary, Annotation, Comparison, and Visualization of Copy Number Variant, Copy Number Variation Region, and Runs of Homozygosity

Frontiers in Genetics, 2021
Detection of CNVs (copy number variants) and ROH (runs of homozygosity) from SNP (single nucleotide polymorphism) genotyping data is often required in genomic studies.
Jinghang Zhou, Jinghang Zhou, Liyuan Liu, Liyuan Liu, Thomas J. Lopdell, Dorian J. Garrick, Yuangang Shi   +6 more
doaj   +1 more source

Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis [PDF]

, 2005
BACKGROUND AND AIMS: The MDR1 gene encodes P-glycoprotein 170, an efflux transporter that is highly expressed in intestinal epithelial cells. The MDR1 exonic single nucleotide polymorphisms (SNPs) C3435T and G2677T have been shown to correlate with ...
Arnott, Ian D, Drummond, Hazel, Fennell, Janice, Ho, Gwo-Tzer, Mowat, Craig, Nimmo, Elaine R, Satsangi, Jack, Tenesa, Albert   +7 more
core   +1 more source

Association of ABCB1, 5-HT3B receptor and CYP2D6 genetic polymorphisms with ondansetron and metoclopramide antiemetic response in Indonesian cancer patients treated with highly emetogenic chemotherapy. [PDF]

, 2011
Our study shows that in Indonesian cancer patients treated with highly cytostatic emetogenic, carriership of the CTG haplotype of the ABCB1 gene is related to an increased risk of delayed chemotherapy-induced nausea and ...
Baak-Pablo, Renee F, Gelderblom, Hans, Guchelaar, Henk-Jan, Hakimi, Mohammad, Mustofa, Mustofa, Nortier, Johann W R, Perwitasari, Dyah A, van der Straaten, Robert J H M, Wessels, Judith A M   +8 more
core   +2 more sources

Family-Based Haplotype Estimation and Allele Dosage Correction for Polyploids Using Short Sequence Reads

Frontiers in Genetics, 2019
DNA sequence reads contain information about the genomic variants located on a single chromosome. By extracting and extending this information using the overlaps between the reads, the haplotypes of an individual can be obtained.
Ehsan Motazedi, Ehsan Motazedi, Chris Maliepaard, Richard Finkers, Richard Visser, Dick de Ridder   +5 more
doaj   +1 more source

Efficient Sequencing, Assembly, and Annotation of Human KIR Haplotypes

Frontiers in Immunology, 2020
The homology, recombination, variation, and repetitive elements in the natural killer-cell immunoglobulin-like receptor (KIR) region has made full haplotype DNA interpretation impossible in a high-throughput workflow.
David Roe, Jonathan Williams, Keyton Ivery, Jenny Brouckaert, Nick Downey, Chad Locklear, Rui Kuang, Rui Kuang, Martin Maiers   +8 more
doaj   +1 more source

phylogenetic study of the Mongolian Tree Pipit (Anthus trivialis, Linnaeus, 1758) population based on mitochondrial DNA (mtDNA) genes

Proceedings of the Mongolian Academy of Sciences
Our aim was to identify nucleotide polymorphisms, assess their distribution in haplotype diversity, and construct a phylogenetic tree by analyzing mtDNA markers of the Mongolian Tree Pipits(Anthus trivialis).
Ulziisaikhan Tumendemberel, Sod-erdene Byambadash, Gabor Sramko, Tserendulam Batsukh   +3 more
doaj   +1 more source

Clinical and Metabolic Signatures of FAM47E–SHROOM3 Haplotypes in a General Population Sample

Kidney International Reports
Introduction: Genome-wide association studies (GWAS) identified a locus on chromosome 4q21.1, spanning the Family With Sequence Similarity 47 Member E (FAM47E), Starch Binding Domain 1 (STBD1), Coiled-Coil Domain Containing 158 (CCDC158), and Shroom ...
Dariush Ghasemi-Semeskandeh, Eva König, Luisa Foco, Nikola Dordevic, Martin Gögele, Johannes Rainer, Markus Ralser, Dianne Acoba, Francisco S. Domingues, Dorien J.M. Peters, Peter P. Pramstaller, Cristian Pattaro   +11 more
doaj   +1 more source

A common variant associated with dyslexia reduces expression of the KIAA0319 gene [PDF]

, 2013
This work was supported by the Wellcome Trust (MYD, SP, TSS, JCK, RWM, PC, SB, and APM), the Intramural Research Programs of the National Human Genome Research Institute (MYD and EDG) and National Cancer Institute (MPO), and the NIH/Ox-Cam Graduate ...
Beck, Stephan, Coggill, Penny, Dennis, Megan Y., Green, Eric D., Knight, Julian C., Monaco, Anthony P., Paracchini, Silvia, Prokunina-Olsson, Ludmila, Scerri, Thomas S., Wade-Martins, Richard   +9 more
core   +1 more source