Results 11 to 20 of about 209,468 (302)
A Bayesian Hierarchical Model for Detecting Haplotype-Haplotype and Haplotype-Environment Interactions in Genetic Association Studies [PDF]
Human Heredity, 2011 <i>Objective: </i>Genetic association studies based on haplotypes are powerful in the discovery and characterization of the genetic basis of complex human diseases. However, statistical methods for detecting haplotype-haplotype and haplotype-environment interactions have not yet been fully developed owing to the difficulties encountered ...
Jun, Li, Kui, Zhang, Nengjun, Yi
openaire +3 more sources
Haplotype reconstruction error as a classical misclassification problem [PDF]
, 2008 Statistically reconstructing haplotypes from single nucleotide polymorphism (SNP) genotypes, can lead to falsely classified haplotypes. This can be an issue when interpreting haplotype association results or when selecting subjects with certain ...
Heid, Iris M. +3 more
core +1 more source
Haplotype-resolved genome assembly, gene annotation and repeat annotation of Coriaria nepalensis.
, 2023 Haplotype-resolved genome assembly, gene annotation and repeat annotation of Coriaria ...
Tian-Le Shi (8873099) +16 more
core +1 more source
Genotyping of invasive Ponto-Caspian gobies in Croatia [PDF]
Journal of Central European Agriculture, 2020 The biology and ecology of non-native freshwater Ponto-Caspian (P-C) gobies: monkey goby, Neogobius fluviatilis (Pallas, 1814), round goby, Neogobius melanostomus (Pallas, 1814) and bighead goby, Ponticola kessleri (Günther, 1861) have been studied in ...
Goran Jakšić +6 more
doaj +1 more source
Association of smoking behavior with an odorant receptor allele telomeric to the human major histocompatibility complex [PDF]
, 2008 Smoking behavior has been associated in two independent European cohorts with the most common Caucasian human leukocyte antigen (HLA) haplotype (A1-B8-DR3). We aimed to test whether polymorphic members of the two odorant receptor (OR) clusters within the
Yu CY +28 more
core +1 more source
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
Single-nucleotide polymorphisms, mapping and association analysis of 1-FFT-A1 gene in wheat
Journal of Integrative Agriculture, 2017 Fructans are major nonstructural carbohydrates in wheat (Triticum aestivum L.). Fructan 1-fructosyltransferase (1-FFT) is the key enzyme in fructan biosynthesis. In the present study, 96 sequence variants were detected in the 1-FFT-A1 gene among 26 wheat
Ai-qin YUE +5 more
doaj +1 more source
Frontiers in Immunology, 2020 Human chromosome 19q13.4 contains genes encoding killer-cell immunoglobulin-like receptors (KIR). Reported haplotype lengths range from 67 to 269 kb and contain 4 to 18 genes.
David Roe +7 more
doaj +1 more source
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions [PDF]
, 2008 Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organisms.
Coin, LJM +15 more
core +1 more source
The Saudi Journal of Gastroenterology, 2014 Background/Aim: Phospholipase C epsilon 1 (PLCE1) plays a crucial role in carcinogenesis and progression of several types of cancers. A single nucleotide polymorphism (SNP, rs2274223) in PLCE1 has been identified as a novel susceptibility locus.
Manzoor A Malik +3 more
doaj +1 more source