Results 21 to 30 of about 135,110 (255)

Genetic diversity of Xanthomonas citri subsp. citri in citrus orchards in northwest Paraná state, Brazil

open access: yesPhytopathologia Mediterranea, 2017
Xanthomonas citri subsp. citri, which causes Asiatic citrus canker (ACC), is an important pathogen of citrus in Brazil and elsewhere. The genetic diversity of X. citri subsp.
Aline GONÇALVES-ZULIANI   +5 more
doaj   +1 more source

Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country

open access: yesFrontiers in Microbiology, 2020
Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). By haplotype analysis of 6,356 US isolates, we identified a pattern of strongly localized outbreaks at the ...
Lishuang Shen   +8 more
doaj   +1 more source

GIPR rs10423928 and bone mineral density in postmenopausal women in Shanghai

open access: yesEndocrine Connections, 2022
We demonstrated previously that there is a correlation between glucagon-like peptide-1 (GLP-1) single-nucleotide polymorphism (SNP) and bone mineral density in postmenopausal women.
Lizhi Zhang   +5 more
doaj   +1 more source

Molecular characterization of the noble crayfish (Astacus astacus L.) population from Pomeranian lakes (north-western Poland) based on mitochondrial DNA

open access: yesKnowledge and Management of Aquatic Ecosystems, 2016
The genetic variability between individuals from five crayfish (Astacus astacus L.) populations was determined. The analysis was based on sequences variations of mitochondrial DNA (cytochrome oxidase subunit I (COI) and 16S ribosomal
Skuza L.   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

BjuB05.GS1.4 promotes nitrogen assimilation and participates in the domestication of shoot nitrogen use efficiency in Brassica juncea

open access: yesJournal of Integrative Agriculture
Elucidating crops’ physiological and molecular mechanisms to adapt to low nitrogen environment and promoting nitrogen transfer from senescent leaves to new leaves is crucial in improving Brassica’s nitrogen use efficiency (NUE). Glutamine synthetase gene
Rumeng Wang   +7 more
doaj   +1 more source

The association of 20 short tandem repeat loci of autosomal chromosome with male schizophrenia

open access: yesBrain and Behavior, 2022
Introduction Schizophrenia's heritability and familial transmission have been known for several decades. The male‐specific Y chromosome plays an important role in schizophrenia.
Chun Yang   +3 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

The TaMYB44–TaMYB1 module regulates grain amylose biosynthesis and flour viscosity in wheat

open access: yesPlant Communications
Starch content and composition in wheat endosperm are critical determinants of wheat yield and quality. Amylose content is a key parameter used to characterize starch viscosity in wheat flour, which influences pasting time, peak viscosity, and ...
Sen Li   +9 more
doaj   +1 more source

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