Results 51 to 60 of about 407,509 (363)

Chromosome-scale, haplotype-resolved assembly of human genomes

Nature Biotechnology, 2020
Haplotype-resolved or phased genome assembly provides a complete picture of genomes and their complex genetic variations. However, current algorithms for phased assembly either do not generate chromosome-scale phasing or require pedigree information ...
Shilpa Garg, Arkarachai Fungtammasan, Andrew Carroll, Mike Chou, Anthony Schmitt, Xiang Zhou, Stephen Mac, P. Peluso, Emily Hatas, Jay Ghurye, Jr. Gerald Q. Maguire, M. Mahmoud, Haoyu Cheng, Davide Heller, J. Zook, Tobias Moemke, T. Marschall, F. Sedlazeck, John D Aach, Chen-Shan Chin, G. M. Church, Heng Li   +21 more
semanticscholar   +1 more source

Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance

Advanced Science, EarlyView.
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei, Junbin Chen, Chuang Liu, DanDan Liu, Meida Du, Shengfeng He, Wenyu Cheng, Vijai Bhadauria, You‐Liang Peng, Wangsheng Zhu   +9 more
wiley   +1 more source

phylogenetic study of the Mongolian Tree Pipit (Anthus trivialis, Linnaeus, 1758) population based on mitochondrial DNA (mtDNA) genes

Proceedings of the Mongolian Academy of Sciences
Our aim was to identify nucleotide polymorphisms, assess their distribution in haplotype diversity, and construct a phylogenetic tree by analyzing mtDNA markers of the Mongolian Tree Pipits(Anthus trivialis).
Ulziisaikhan Tumendemberel, Sod-erdene Byambadash, Gabor Sramko, Tserendulam Batsukh   +3 more
doaj   +1 more source

Steelhead (Oncorhynchus mykiss) lineages and sexes show variable patterns of association of adult migration timing and age‐at‐maturity traits with two genomic regions

Evolutionary Applications, 2020
As life history diversity plays a critical role in supporting the resilience of exploited populations, understanding the genetic basis of those life history variations is important for conservation management.
Stuart C. Willis, Jon E. Hess, Jeff K. Fryer, John M. Whiteaker, Chris Brun, Ryan Gerstenberger, Shawn R. Narum   +6 more
doaj   +1 more source

Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle

Nature Communications, 2020
Inbred animals were historically chosen for genome analysis to circumvent assembly issues caused by haplotype variation but this resulted in a composite of the two genomes.
W. Low, R. Tearle, Ruijie Liu, S. Koren, A. Rhie, D. Bickhart, B. Rosen, Zev N. Kronenberg, S. Kingan, Elizabeth Tseng, F. Thibaud-Nissen, Fergal J. Martin, Konstantinos Billis, Jay Ghurye, A. Hastie, Joyce Lee, A. Pang, M. P. Heaton, A. Phillippy, S. Hiendleder, T. Smith, J. Williams   +21 more
semanticscholar   +1 more source

A Transmembrane Protein WAI‐B2 Confers Multiple Disease Resistance in Wheat by Activating Autoimmunity

Advanced Science, EarlyView.
Wheat production is under threat from multiple diseases. This study clones the wheat autoimmunity gene WAI‐B2 from an EMS‐induced mutant that encodes a distinct transmembrane protein conferring resistance to wheat rusts and powdery mildew ‐ two major diseases affecting wheat crops.
Wenling Li, Yongxing Chen, Lei Dong, Guanghao Guo, Huaizhi Zhang, Tao Shen, Gaojie Wang, Lingli Dong, Ping Lu, Miaomiao Li, Dan Qiu, Keyu Zhu, Beibei Li, Yikun Hou, Xuejia Cui, Baoge Huang, Fugang Yang, Hongkui Fu, Delin Li, Zhan Li, Jinghuang Hu, Yunfeng Qu, Huanhuan Lou, Shisheng Chen, Zaifeng Li, Ling Kang, Wuyun Yang, Chengguo Yuan, Hongjie Li, Yusheng Zhao, Zhiyong Liu, Haiyan Jia, Qiuhong Wu   +32 more
wiley   +1 more source

Clinical and Metabolic Signatures of FAM47E–SHROOM3 Haplotypes in a General Population Sample

Kidney International Reports
Introduction: Genome-wide association studies (GWAS) identified a locus on chromosome 4q21.1, spanning the Family With Sequence Similarity 47 Member E (FAM47E), Starch Binding Domain 1 (STBD1), Coiled-Coil Domain Containing 158 (CCDC158), and Shroom ...
Dariush Ghasemi-Semeskandeh, Eva König, Luisa Foco, Nikola Dordevic, Martin Gögele, Johannes Rainer, Markus Ralser, Dianne Acoba, Francisco S. Domingues, Dorien J.M. Peters, Peter P. Pramstaller, Cristian Pattaro   +11 more
doaj   +1 more source

Family-Based Haplotype Estimation and Allele Dosage Correction for Polyploids Using Short Sequence Reads

Frontiers in Genetics, 2019
DNA sequence reads contain information about the genomic variants located on a single chromosome. By extracting and extending this information using the overlaps between the reads, the haplotypes of an individual can be obtained.
Ehsan Motazedi, Ehsan Motazedi, Chris Maliepaard, Richard Finkers, Richard Visser, Dick de Ridder   +5 more
doaj   +1 more source

Monitoring drought responses of barley genotypes with semi-robotic phenotyping platform and association analysis between recorded traits and allelic variants of some stress genes [PDF]

, 2013
Genetic improvement of complex traits such as drought adaptation can be advanced by the combination of genomic and phenomic approaches. Semi-robotic phenotyping platform was used for computer-controlled watering, digital and thermal imaging of barley ...
Cseri, András, Dudits, Dénes, Pauk, János, Sass, László, Törjék, Ottó, Vass, Imre   +5 more
core  

A Pan‐TE Map Reveals the Important Role of Transposable Elements in Gene Expression and Phenotypic Diversity in 2,311 Rapeseed Accessions

Advanced Science, EarlyView.
This study presents the first pan‐transposable element (TE) atlas in rapeseed, profiling over 8 million TEs across 2311 accessions. Integrative analyses reveal that TEs broadly shape gene expression through diverse regulatory mechanisms, with key insertions in BnaA03.FLC and BnaA09.CYP78A9 linked to flowering time and silique development.
Zhiquan Yang, Haiyan Fan, Yifan Chen, Jiawei Li, Minjian Chen, Yingying Tan, Liang Guo, Jintao Li, Kede Liu, Qing‐Yong Yang   +9 more
wiley   +1 more source