Results 61 to 70 of about 209,468 (302)
American Journal of Hematology, EarlyView.ABSTRACT Although circulating nucleated red blood cells (cNRBCs) have previously been detected in patients with sickle cell disease (SCD), their prevalence and clinical significance during steady‐state disease have not been established. We retrospectively analyzed 270 adults with an SS or Sβ0‐thalassemia genotype.
Ugo Boccadifuoco +7 more
wiley +1 more source
, 2019 Haplotype-based associations with relatively major effects (>15%) for the traits of leaf angle (LA), ear height (EH), plant height (PH) and the EH/PH ratio, measured in inbred lines of tropical maize during two growing seasons.
Carlos Maldonado (5527520) +3 more
core +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Genetic modifiers of Duchenne muscular dystrophy (DMD) that alter disease severity or response to therapy have been reported using natural history or registry data sets of older corticosteroid‐treated patients. We tested associations of genetic modifiers on motor function outcomes in young (4 to < 7 years) steroid naïve clinical trial ...
Utkarsh J. Dang +16 more
wiley +1 more source
Computational analyses of ancient pathogen DNA from herbarium samples: challenges and prospects
Frontiers in Plant Science, 2015 The application of DNA sequencing technology to the study of ancient DNA has enabled the reconstruction of past epidemics from genomes of historically important plant-associated microbes.
Kentaro eYoshida +3 more
doaj +1 more source
Frontiers in Psychiatry, 2020 BackgroundIn psychiatric illness, pathogenic role of neuroinflammation has been supported by multiple lines of evidence. Astrocytes contribute to the blood-brain barrier (BBB) with formation of the “glymphatic” drainage system of the central nervous ...
Yung-Fu Wu +4 more
doaj +1 more source
Haplotype analysis in block 1.
, 2013 Haplotypes are constructed. Case ratio means in the case group, the frequency of this kind of haplotype vs. other kinds of haplotype; control ratio means in the control group, the frequency of this kind of haplotype vs. other kinds of haplotype.
Jingyi Liu (400542) +5 more
core +1 more source
A Common Variant Associated with Dyslexia Reduces Expression of the KIAA0319 Gene [PDF]
, 2009 Numerous genetic association studies have implicated the KIAA0319 gene on human chromosome 6p22 in dyslexia susceptibility. The causative variant(s) remains unknown but may modulate gene expression, given that (1) a dyslexia-associated haplotype has been
Penny Coggill +42 more
core +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Biallelic variants in NSMCE2 (MMS21), which encodes the SUMO E3 ligase subunit of the SMC5/6 chromatin‐maintenance complex, have recently been implicated in microcephalic primordial dwarfism (MPD), corresponding to Seckel syndrome type 10 (OMIM #617246).
Cristina Peduto +5 more
wiley +1 more source
The Role of Glutamatergic and Dopaminergic Genes in Resistant Schizophrenia: A Systematic Review
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Psychosis is a heterogeneous disorder, with approximately one‐third of patients experiencing treatment resistance, predominantly among individuals diagnosed with Schizophrenia. Treatment‐resistant schizophrenia (TRS) may stem from a distinct biological signature, involving abnormalities in the dopaminergic and glutamatergic systems.
Maria Teresa Moreno‐Calle +3 more
wiley +1 more source
Linking unfounded beliefs to genetic dopamine availability
Frontiers in Human Neuroscience, 2015 Unfounded convictions involving beliefs in the paranormal, grandiosity ideas or suspicious thoughts are endorsed at varying degrees among the general population.
Katharina eSchmack +6 more
doaj +1 more source