Results 131 to 140 of about 229,423 (345)

In Vitro Assessment of Drug‐Induced Liver Injury Using Three‐Dimensional Cultured HepaSH Cells Derived From Chimeric Mouse Model With Humanized Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Drug‐induced liver injury (DILI) is a serious adverse event and a common cause of postmarketing drug withdrawal. Despite nonclinical assessments of DILI risk, which are predominantly conducted in experimental animals, DILI remains a frequent adverse event, highlighting the need to improve nonclinical assessments.
Xingming Liu, Yuichiro Higuchi, Yuta Sakamoto, Shota Yanagida, Shotaro Uehara, Hiroshi Suemizu, Yasunari Kanda, Hiroyuki Kawagishi   +7 more
wiley   +1 more source

Morpometric and molecular characterization of Surguli goat through CO1 gene in district Kohat

Animal Biotechnology
The present study was designed with the aim to study morphometric characterization as well as phylogeny and diversity of the local Surguli goat at their breeding tract district Kohat through mitochondrial DNA region, i.e., Cytochrome C Oxidase Subunit ...
Muhammad Munir Khan, Syed Muhammad Suhail, Hafiz Abdul Majid, Ijaz Ahmad, Umer Sadique, Rajwali Khan, Iftikhar Ahmad, Asim Ijaz, Khalid Khan, Farhad Ali, Muhammad Saeed Khan, Ahmed A. El-Mansi   +11 more
doaj   +1 more source

The H-2 haplotype of the PN (Palmerston North) inbred strain [PDF]

, 1982
Jane S. Schultz, Sara E. Walker, Chella S. David   +2 more
openalex   +1 more source

De Novo Whole Genome Assemblies of Unusual Case‐Making Caddisflies (Trichoptera) Highlight Genomic Convergence in the Composition of the Major Silk Gene (h‐fibroin)

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
The major silk gene, h‐fibroin, was annotated in high‐quality genomes of two unusual case‐making Trichoptera. H‐Fibroin of Limnocentropus insolitus shows a similar amino acid composition to other case‐making species, while the amino acid composition of h‐fibroin of Phryganopsyche brunnea resembles that of retreat‐making species.
Xiling Deng, Steffen U. Pauls, Ryoichi B. Kuranishi, Paul B. Frandsen, Jacqueline Heckenhauer   +4 more
wiley   +1 more source

Two distinct HLA-DR3 haplotypes are associated with age related heterogeneity in Type 1 (insulin-dependent) diabetes [PDF]

, 1988
I Deschamps, A Marcelli-Barge, J. C. Poirier, Odile Cohen‐Haguenauer, Hadi Abderrahim, Daniel Cohen, H Lestradet, J Hors   +7 more
openalex   +1 more source

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

Genetic Epidemiology, 2010
Yun Li, C. Willer, Jun Ding, P. Scheet, G. Abecasis   +4 more
semanticscholar   +1 more source

Impact of placental and peripheral blood DNA methylation on celiac disease susceptibility

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Several studies suggest that the first immunogenic insult in celiac disease (CeD) could occur during fetal development. The placenta is a key organ that could link the environment with the genome and future outcomes, including CeD.
Alba Hernangomez‐Laderas, Ariadna Cilleros‐Portet, Mikel de la Peña‐Sanz, Sergi Marí, Corina Lesseur, Itziar González‐Moro, Bárbara P. González‐García, Jia Chen, Iraia García‐Santisteban, Carmen J. Marsit, Jose Ramon Bilbao, Nora Fernandez‐Jimenez   +11 more
wiley   +1 more source

Recombination between two mouset-haplotypes (t^w12tfandt^Lub-1): segregation of lethal factors relative to centromere and tufted (tf) locus [PDF]

, 1983
Hubert Condamine, Jean‐Louis Guénet, François Jacob   +2 more
openalex   +1 more source

Chronic atrial and intestinal dysrythmia syndrome: A late‐onset intestinal pseudo‐obstruction and cardiac dysfunction due to an SGO1 mutation

JPGN Reports, EarlyView.
Abstract Objectives Pediatric intestinal pseudo‐obstruction (PIPO) is a rare, heterogeneous, and severe gut motility disorder. In 2014, Chetaille et al. described chronic atrial and intestinal dysrhythmia (CAID) syndrome associated with a recessive SGO1 mutation (p.Lys23Glu) linking it to both intestinal pseudo‐obstruction and cardiac dysrhythmia. This
Linda Adouane, Pierre Poinsot, Julie Castilloux, Dorothée Dal Soglio, Christophe Faure   +4 more
wiley   +1 more source

Role of the H-2s haplotype in survival of mice after infection with Trypanosoma cruzi [PDF]

, 1984
Ruth A. Wrightsman, Stuart M. Krassner, J D Watson, Jerry E. Manning   +3 more
openalex   +1 more source