Results 171 to 180 of about 109,284 (237)

Mitochondrial DNA phylogeography of a species-specific sucking louse, Johnsonpthirus heliosciuri, act as a proxy to provide insights into the population connectivity of its host, smith's bush squirrels, Paraxerus cepapi. [PDF]

Parasitol Res
Raubenheimer I, Matthee S, Wentzel J, Matthee CA.   +3 more
europepmc   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

Brain Pathology, EarlyView.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown, Jeanne K. Brooks, Louise Kelly, Madeline M. Vroom, Matthew Longo, Jean‐Cosme Dodart, Roxana Carare, Justin D. Boyd   +7 more
wiley   +1 more source

Exploring standing genetic variation for barley leaf rust resistance in Australian breeding panel. [PDF]

Theor Appl Genet
Pandit M, Dracatos P, Periyannan S, Lam Y, Brunner SM, Honse T, Tong J, Dinglasan E, Ganesalingam D, Moody D, Baraibar S, Hickey L, Alahmad S, Robinson H.   +13 more
europepmc   +1 more source

Genetic diversity analysis of sorghum grain traits and development of KASP markers for grain width genes SbTGW3 and SbGS5. [PDF]

BMC Plant Biol
Wang H, Li J, He M, Zhang R, Wu Y, Zhao J, Zhang Y, Liu Q.   +7 more
europepmc   +1 more source

Fetal Fraction Signatures: A Quality Control Tool to Detect Potentially Confounding Situations in NonInvasive Prenatal Diagnosis of Monogenic Conditions

Clinical Genetics, EarlyView.
Noninvasive prenatal diagnosis for monogenic diseases (NIPD‐M) to detect inherited mutations is performed in parallel with fetal fraction signatures, to detect various anomalies that may compromise diagnosis. An extra regression analysis may be necessary to resolve mosaic situations. ABSTRACT Noninvasive prenatal diagnosis relies on the analysis of the
Jean‐Louis Blouin, Claudine Rieubland, Thierry Nouspikel   +2 more
wiley   +1 more source

The fungal pathogen Rhizoctonia solani AG-8 has 2 nuclear haplotypes that differ in abundance. [PDF]

G3 (Bethesda)
Sperschneider J, DeBoer K, Singh KB, Vadakattu GVSR, Anderson J.   +4 more
europepmc   +1 more source

Expanding Phenotype of GINS1 Deficiency: A Case Report and Review of the Literature

Clinical Genetics, EarlyView.
The authors present a novel case and review of individuals with GINS1 deficiency, causing severe growth restriction and combined immunodeficiency. Only the ninth case of this ultrarare disorder, it highlights the role of these variants in disease, glaucoma as a feature, and the possibility of immunodeficiency without infections in affected individuals.
Michael P. Mackley, Rae Brager, Hannah Geddie, Vicky Breakey, Rebecca Hough, Dimitrios J. Stavropoulos, Vanda McNiven   +6 more
wiley   +1 more source

Population of Northern Portugal: Study of Genetic Diversity and Forensic Parameters of 26 Y-STR Markers. [PDF]

Genes (Basel)
Maia B, Fadoni J, Cainé L, Souto L, Amorim A.   +4 more
europepmc   +1 more source

Clinical‐Grade Human Induced Pluripotent Stem Cell‐Derived Neural Precursor Cells Restore Motor Function and Preserve Striatal Integrity in a Quinolinic Acid‐Lesioned Rat Model of Huntington's Disease

Cell Proliferation, EarlyView.
Clinical‐grade HLA‐homozygous iPSC‐derived neural precursor cells restore motor function, rebuild striatal circuitry and reduce neuroinflammation in QA‐lesioned rats. These findings demonstrate robust neuronal replacement and microenvironment modulation, supporting their potential as a regenerative therapy for Huntington's disease.
Hyeonjoong Jeon, Il‐Shin Lee, Sanghun Lee, Hyo Chang Park, Beomsoo Kim, Hyun Sook Kim, Jihwan Song   +6 more
wiley   +1 more source

Genomic Insights into Winter Wheat Breeding for Severely Cold Climates. [PDF]

Int J Mol Sci
Sertse D, Bekele WA, McCartney CA.
europepmc   +1 more source