Results 181 to 190 of about 111,740 (256)

Rapid and reproducible haplotyping of complete mitochondrial genomes using split k-mers. [PDF]

BMC Genomics
Stuehler DS, Cano LM, Heck M.
europepmc   +1 more source

Lack of association between vaccine‐induced immune thrombocytopenia and thrombosis and HLA loci in a large cohort

British Journal of Haematology, EarlyView.
Linda Schönborn, Ana Tzvetkova, Thomas Thiele, Uwe Völker, Sabine Ameling, Sören Franzenburg, Lars Kaderali, Andreas Greinacher   +7 more
wiley   +1 more source

The insulin‐like growth factor system and the progression of renal complications of type 2 diabetes

Diabetic Medicine, EarlyView.
Abstract Aims Chronic kidney disease is associated with dysregulation of the insulin‐like growth factor (IGF) system. Alterations in IGF bioavailability, driven by IGF binding proteins (IGFBPs), may influence the decline in renal function. However, the longitudinal relationship between baseline IGF‐I, IGF‐II, IGFBPs and progression of kidney ...
Adrian Heald, Yasitha lllangasekera, Andreas Matheou, Ram Prakash Narayanan, Stephen White, Hellena Habte‐Asres, Abigail Lay, Liliana Shalamanova, William Ollier, Graham A. Hitman, Ritwika Mallik, Philip A. Kalra, Martin Whyte, J. Martin Gibson   +13 more
wiley   +1 more source

Conservation Hotspots of <i>Quercus castaneifolia</i> Revealed Through the Integration of Genetic Diversity and Landscape Connectivity. [PDF]

Ecol Evol
Shahnaseri G, Malekian M, Müller M, Gailing O.   +3 more
europepmc   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source

Genetic Diversity and Impacts of Stocking on Cyprinus carpio Populations in Türkiye: Insights From Mitochondrial, Nuclear, and Microsatellite Markers

Fisheries Management and Ecology, EarlyView.
ABSTRACT Understanding genetic diversity and population structure is essential for the sustainable management of widely stocked freshwater species such as common carp (Cyprinus carpio). In this study, we conducted a comprehensive genetic assessment of C.
Meryem Cansu Yesiltaş, Rafet Çağrı Öztürk, Emre Keskin, Ilhan Altinok   +3 more
wiley   +1 more source

Fine‐scale patterns of genetic structure in three species of forest birds reveal dynamic Pleistocene history within an Amazonian interfluve

Ibis, EarlyView.
Phylogeographical studies of Amazonian birds have revealed large intraspecific diversity, even within recognized areas of endemism. To understand the origin and organization of Amazonian diversity, including the influence of current and historical landscapes, we need to evaluate fine‐scale patterns of genetic diversity in relation to detailed ...
Affonso Henrique Nascimento de Souza, Camila Duarte Ritter, João Marcos Guimarães Capurucho, Juliana Menger, Camila Cherem Ribas   +4 more
wiley   +1 more source

Towards haplotypes of blood group genes: the impact of long-read sequencing in molecular immunohematology. [PDF]

Ann Transl Med
Wörner L, Bugert P.
europepmc   +1 more source

Functional immune profiling reveals CD4+ T cell dysregulation in coeliac disease

Immunology &Cell Biology, EarlyView.
The T cell momentum assay quantifies division, survival and activation decay to reveal intrinsic CD4+ programming defects marked by prolonged activation and impaired feedback control in coeliac disease. This scalable platform provides a functional screen for early T cell dysregulation across autoimmune and immune‐mediated diseases.
Anthony J Farchione, HoChan Cheon, David Vremec, Julika Neumann, Gwenny M Verstappen, Melinda Y Hardy, Mai B Margetts, Lauren J Howson, Lee M Henneken, Maureen Forde, Jason A Tye‐Din, Susanne Heinzel, Philip D Hodgkin, Vanessa L Bryant   +13 more
wiley   +1 more source

Comparative genomics of different haplotypes in Ditylenchus destructor provides insights into their host preferences. [PDF]

Commun Biol
Zhao Z, Zhang H, Wang J, Luo N, Li H, Lin R, Xie B.   +6 more
europepmc   +1 more source