Results 51 to 60 of about 109,284 (237)

Pure Parsimony Xor Haplotyping [PDF]

IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2009
The haplotype resolution from xor-genotype data has been recently formulated as a new model for genetic studies. The xor-genotype data is a cheaply obtainable type of data distinguishing heterozygous from homozygous sites without identifying the homozygous alleles.
BONIZZONI, PAOLA, DELLA VEDOVA, GIANLUCA, Dondi, R, PIROLA, YURI, Rizzi, R.   +4 more
openaire   +8 more sources

Pan‐3D Genome Analysis Reveals the Roles of Structural Variation in Chicken Chromatin Architectures, Domestication and Production Traits

Advanced Science, EarlyView.
This study firstly presents a comprehensive and high‐resolution pan‐3D genome resource in chicken. Our findings reveal the role of structural variations in 3D genome architectures, and how they influence the domestication process and production traits at the 3D genome level.
Zhen Zhou, Danfeng Cai, Changbin Zhao, Siyu Zhang, Jiahao Li, Zhaofeng Zhang, Shaofen Kong, Xin Yang, Xiaoli Zhou, Farhad Bordbar, Fayi Chen, Yaohuan Xu, Zhe Zhang, Lihong Gu, Zhenhui Li, Xiquan Zhang, Wen Luo, Jingting Shu, Bolin Cai, Qinghua Nie   +19 more
wiley   +1 more source

Frecuencias alélicas, genotípicas y haplotípicas HLA-A, HLA-B, HLA-DRB1 en donantes fallecidos, Medellín, Colombia

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. La caracterización genética del sistema HLA es de gran utilidad en estudios antropogenéticos, en la comprensión de mecanismos asociados a susceptibilidad o resistencia a diversas enfermedades, en los fenómenos inmunológicos durante el ...
Libia M. Rodríguez, Mabel C. Giraldo, Natalia García, Laura Velásquez, Sara C. París, Cristiam M. Álvarez, Luis F. García   +6 more
doaj   +1 more source

Long-range, high-throughput haplotype determination via haplotype-fusion PCR and ligation haplotyping [PDF]

Nucleic Acids Research, 2008
Ligation Haplotyping is a robust, novel method for experimental determination of haplotypes over long distances, which can be applied to assaying both sequence and structural variation. The simplicity and efficacy of the method for genotyping large chromosomal rearrangements and haplotyping SNPs over long distances make it a valuable and powerful ...
Turner, Daniel J., Tyler-Smith, Chris, Hurles, Matthew E.   +2 more
openaire   +2 more sources

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

Advanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei, Wenzhu Peng, Zekun Huang, Bingye Yang, Yiyu Wu, Minzhen Han, Yi Wang, Bingling Peng, Guosheng Hu, Jiawei Hong, Guijia Liu, Linwei Nie, Yang Gan, Miaoqin Huang, Xuan Luo, Weiwei You, Wen Liu, Caihuan Ke   +17 more
wiley   +1 more source

Development of chloroplast microsatellite markers for Glyptostrobus pensilis (Cupressaceae)

Applications in Plant Sciences, 2019
Premise Glyptostrobus pensilis (Cupressaceae) is a critically endangered conifer native to China, Laos, and Vietnam, with only a few populations remaining in the wild. Methods and Results Using a complete chloroplast genome sequence, we designed 70 cpSSR
Ya‐Dan Yan, Xin‐Yu Li, James R. P. Worth, Xue‐Ying Lin, Markus Ruhsam, Lu Chen, Xing‐Tong Wu, Min‐qiu Wang, Philip I. Thomas, Ya‐Feng Wen   +9 more
doaj   +1 more source

Asociación de variantes en genes de las proteínas desacoplantes con diabetes mellitus tipo 2 en una población del nordeste colombiano

Biomédica: revista del Instituto Nacional de Salud, 2009
Introducción. Las proteínas desacoplantes pertenecen a la familia de proteínas transportadoras de aniones que desacoplan la producción de ATP de la respiración mitocondrial, causando pérdida de protones a través de la membrana mitocondrial interna y ...
Liliana Franco-Hincapié, Constanza Elena Duque, María Victoria Parra, Natalia Gallego, Alberto Villegas, Andrés Ruiz-Linares, Gabriel Bedoya   +6 more
doaj   +1 more source

Haplotype inference for present–absent genotype data using previously identified haplotypes and haplotype patterns [PDF]

Bioinformatics, 2007
AbstractMotivation: Killer immunoglobulin-like receptor (KIR) genes vary considerably in their presence or absence on a specific regional haplotype. Because presence or absence of these genes is largely detected using locus-specific genotyping technology, the distinction between homozygosity and hemizygosity is often ambiguous.
Yun Joo, Yoo, Jianming, Tang, Richard A, Kaslow, Kui, Zhang   +3 more
openaire   +2 more sources

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

High-throughput haplotype determination over long distances by haplotype fusion PCR and ligation haplotyping [PDF]

Nature Protocols, 2009
When combined with haplotype fusion PCR (HF-PCR), ligation haplotyping is a robust, high-throughput method for empirical determination of haplotypes, which can be applied to assaying both sequence and structural variation over long distances. Unlike alternative approaches to haplotype determination, such as allele-specific PCR and long PCR, HF-PCR and ...
Daniel J, Turner, Matthew E, Hurles
openaire   +2 more sources