Results 31 to 40 of about 231,107 (286)

Effects of the number of markers per haplotype and clustering of haplotypes on the accuracy of QTL mapping and prediction of genomic breeding values [PDF]

open access: yes, 2009
The aim of this paper was to compare the effect of haplotype definition on the precision of QTL-mapping and on the accuracy of predicted genomic breeding values.
Mario PL Calus   +28 more
core   +3 more sources

Advances in methodologies for detecting MHC-B variability in chickens

open access: yesPoultry Science, 2020
The chicken major histocompatibility B complex (MHC-B) region is of great interest owing to its very strong association with resistance to many diseases. Variation in the MHC-B was initially identified by hemagglutination of red blood cells with specific
J.E. Fulton
doaj   +1 more source

Multiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malaria. [PDF]

open access: yes, 2009
BACKGROUND: Although the molecular basis of resistance to a number of common antimalarial drugs is well known, a geographic description of the emergence and dispersal of resistance mutations across Africa has not been attempted.
A-Elbasit, Ishraga E   +40 more
core   +5 more sources

Discovery and Validation of Grain Shape Loci in U.S. Rice Germplasm Through Haplotype Characterization

open access: yesFrontiers in Genetics, 2022
Rice grain shape is a major determinant of rice market value and the end-use. We mapped quantitative trait loci (QTL) for grain shape traits in a bi-parental recombinant inbred line population (Trenasse/Jupiter) and discovered two major grain length QTLs—
Brijesh Angira   +2 more
doaj   +1 more source

The mitochondrial DNA HVI and HVII sequences and haplogroup distribution in a population sample from Vietnam

open access: yesAnnals of Human Biology, 2022
Background Mitochondrial DNA (mtDNA) analysis has been used in forensics and requires well-established population databases for statistical interpretations. However, high-quality mtDNA data from Vietnamese population samples have been limited.
Nam Ngoc Nguyen   +7 more
doaj   +1 more source

Determination of linkage disequilibrium region suggests association of the ancient haplotype, hX with neural function [PDF]

open access: yes, 2011
Modern human populations are known to contain "ancient haplotypes" that originated from archaic humans by hybridization. Some of them had been reported before the development of human genomic diversity databases, such as HapMap. Consequently,
Makoto Shimada, Tsutomu Kanasashi
core   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

DNA barcoding of minor fish fauna: a case study in the Province of Bolzano/Bozen, Italy

open access: yesThe European Zoological Journal
The fish fauna of the Province of Bolzano/Bozen (northern Italy) currently includes at least 35 species, mostly defined on a morphological basis. Naturally occurring fish are presumably native to the northern Adriatic Catchment, as the alpine divide is ...
L. Zanovello   +11 more
doaj   +1 more source

alpha-thalassemia, HbS, and beta-globin gene cluster haplotypes in two Afro-Uruguayan sub-populations from northern and southern Uruguay

open access: yesGenetics and Molecular Biology, 2006
Hemoglobinopathies are the most common monogenic disorders worldwide; however, they have never been systematically studied from a genetic perspective in Uruguay. In this study, we determined the frequencies of hemoglobin variants in Afro-Uruguayans.
Julio A. da Luz   +5 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

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