Results 51 to 60 of about 231,107 (286)

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

Advanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei, Wenzhu Peng, Zekun Huang, Bingye Yang, Yiyu Wu, Minzhen Han, Yi Wang, Bingling Peng, Guosheng Hu, Jiawei Hong, Guijia Liu, Linwei Nie, Yang Gan, Miaoqin Huang, Xuan Luo, Weiwei You, Wen Liu, Caihuan Ke   +17 more
wiley   +1 more source

The dystrophinopathies in Costa Rica

Revista de Biología Tropical, 2004
A five-years long study aiming to describe the basic genetic epidemiology of the dystrophinopathies in Costa Rica recruited 31 patients with clinical symptoms of DMD/BMD at the National Children’s Hospital (HNN).
Jorge Azofeifa
doaj  

Origin and Distribution of the VRN-A1 Exon 4 and Exon 7 Haplotypes in Domesticated Wheat Species

Agronomy, 2018
The high adaptive potential of modern wheat to a wide range of environmental conditions is determined by genetic changes during domestication. Genetic diversity in VRN1 genes is a key contributor to this adaptability.
Alexandr Muterko, Elena Salina
doaj   +1 more source

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

Sensitivity towards DMI fungicides and haplotypic diversity of their CYP51 target in the Mycosphaerella graminicola population of Flanders [PDF]

, 2014
Septoria leaf blotch, caused by the fungus Mycosphaerella graminicola, is the most important wheat disease in Northwestern Europe, and is currently controlled by fungicide applications.
Curvers, Katrien, Gheysen, Godelieve, Haesaert, Geert, Kyndt, Tina, Pycke, Bart   +4 more
core   +1 more source

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

Mitochondrial DNA discriminates distinct population of two deadly snakes (Reptilia: Elapidae) in Northeast India

Mitochondrial DNA. Part B. Resources, 2020
The DNA data of Indian snakes are scanty in the global database, especially from the northeastern states. The present study generated the mitochondrial Cytochrome b gene information of two morphologically identified deadly elapid species from Mizoram ...
Shantanu Kundu, Hmar Tlawmte Lalremsanga, Kaomud Tyagi, Lal Biakzuala, Vikas Kumar, Kailash Chandra   +5 more
doaj   +1 more source

Low Diversity and Strong Genetic Structure Between Feeding and Nesting Areas in Brazil for the Critically Endangered Hawksbill Sea Turtle

Frontiers in Ecology and Evolution, 2021
Marine turtle nesting areas are characterized by receiving several females every year. The species Eretmochelys imbricata, known as hawksbill turtle is listed as Critically Endangered by the IUCN, and has been the target of studies on genetic structure ...
Thyara Noely Simões, Ednilza Maranhão dos Santos, Alesandro Souza Santos, Fernanda Amato Gaiotto, Marco Antônio Costa, Elza Thaynara Cardoso de Menezes Assis, Vivian Chimendes da Silva Neves, Werlanne Mendes de Santana Magalhães, Rita Mascarenhas, Waltyane Alves Gomes Bonfim, Juliede Nonato Neves, Mirco Solé, Mirco Solé   +12 more
doaj   +1 more source

Origin of the Jews and the Arabs: Date of their Most Recent Common Ancestor is Written in their Y-Chromosomes - However, There Were Two of Them [PDF]

, 2010
A pattern of Y-chromosomal mutations in 37 and 67 marker haplotypes of the Jews and the Arabs indicates that their most recent common ancestor in haplogroup J1 (subclade J1e*) and that (a different one) in haplogroup J2 (subclade J2a*) lived 4300+/-500 ...
Anatole A. Klyosov
core   +1 more source

Genetic association study of UCMA/GRP and OPTN genes (PDB6 locus) with Paget's disease of bone [PDF]

, 2012
We performed a genetic association study of rare variants and single nucleotide polymorphisms (SNPs) of UCMA/GRP and OPTN genes, in French-Canadian patients with Paget's disease of bone (PDB) and in healthy controls from the same population.
Albagha, Albagha, Avilion, Basu-Roy, Cancela, Chen, Chung, Desmet, Edith Gagnon, Ethel S. Siris, Fahmi, Gabriel Miltenberger-Miltenyi, Goode, Hocking, Jacques P. Brown, Jean Morissette, Laurin, Laurin, Layfield, Laëtitia Michou, Le Jeune, Lefebvre, Lucas, Luu-The, M. Leonor Cancela, Maruyama, Michou, Morissette, Natércia Conceição, Pankiv, Rath, Rezaie, Rousiere, Shankar, Singh, Staden, Surmann-Schmitt, Tagariello, Tong, van Staa, Viegas, Viegas   +41 more
core   +1 more source