Results 11 to 20 of about 231,107 (286)
Pure Parsimony Xor Haplotyping [PDF]
IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2009 The haplotype resolution from xor-genotype data has been recently formulated as a new model for genetic studies. The xor-genotype data is a cheaply obtainable type of data distinguishing heterozygous from homozygous sites without identifying the ...
Bonizzoni, Paola +4 more
core +8 more sources
Mapping Haplotype-haplotype Interactions with Adaptive LASSO [PDF]
BMC Genetics, 2010 AbstractBackgroundThe genetic etiology of complex diseases in human has been commonly viewed as a complex process involving both genetic and environmental factors functioning in a complicated manner. Quite often the interactions among genetic variants play major roles in determining the susceptibility of an individual to a particular disease ...
Li Ming +3 more
openaire +3 more sources
Detecting Local Haplotype Sharing and Haplotype Association [PDF]
Genetics, 2014 Abstract A novel haplotype association method is presented, and its power is demonstrated. Relying on a statistical model for linkage disequilibrium (LD), the method first infers ancestral haplotypes and their loadings at each marker for each individual.
Xu, Hanli, Guan, Yongtao
openaire +2 more sources
Cells, 2022 Plasma concentrations of natriuretic peptides (NP) contribute to risk stratification and management of patients undergoing non-cardiac surgery. However, genetically determined variability in the levels of these biomarkers has been described previously ...
Markus Hahn +5 more
doaj +1 more source
Horticulturae, 2022 Previously developed Annona cherimola specific primers based on the plant barcode gene matK were tested in 546 cherimoya accessions. Of those, 296 belong to an ex situ world reference germplasm collection maintained at the IHSM La Mayora-CSIC-UMA in ...
Nerea Larranaga +4 more
doaj +1 more source
Frontiers in Genetics, 2022 We describe a genome-wide analytical approach, SNP and Haplotype Regional Heritability Mapping (SNHap-RHM), that provides regional estimates of the heritability across locally defined regions in the genome.
Richard F. Oppong +10 more
doaj +1 more source
Search for Risk Haplotype Segments with GWAS Data by Use of Finite Mixture Models [PDF]
, 2015 The region-based association analysis has been proposed to capture the collective behavior of sets of variants by testing the association of each set instead of individual variants with the disease.
Ali, Fadhaa, Zhang, Jian
core +1 more source
Analysis of the VERNALIZATION-A1 exon-4 polymorphism in polyploid wheat
Вавиловский журнал генетики и селекции, 2017 One of the key genes that influence the adaptability of wheat to environments and yield are the VRN1 genes. In recent studies, an association of missense mutations within VERNALIZATION-A1 exon-4 with modulation of quantitative values of such ...
A. F. Muterko, E. A. Salina
doaj +1 more source
Joint Haplotype Assembly and Genotype Calling via Sequential Monte Carlo Algorithm [PDF]
, 2015 Genetic variations predispose individuals to hereditary diseases, play important role in the development of complex diseases, and impact drug metabolism. The full information about the DNA variations in the genome of an individual is given by haplotypes,
Ahn, Soyeon, Vikalo, Haris
core +3 more sources
Minimum error correction-based haplotype assembly: considerations for long read data
, 2020 The single nucleotide polymorphism (SNP) is the most widely studied type of genetic variation. A haplotype is defined as the sequence of alleles at SNP sites on each haploid chromosome.
de Ridder, Dick +2 more
core +1 more source