Results 21 to 30 of about 231,107 (286)

Functional Analysis of Haplotypes in Bovine PSAP Gene and Their Relationship with Beef Cattle Production Traits

Animals, 2020
The purpose of this study was to explore functional variants in the prosaposin (PSAP) three prime untranslated region (3’ UTR) and clarify the relationship between the variants and morphological traits.
Haidong Zhao, Mingli Wu, Xiaohua Yi, Xiaoqin Tang, Pingbo Chen, Shuhui Wang, Xiuzhu Sun   +6 more
doaj   +1 more source

Genetic Differentiation and Population Structure of Threatened Prunus africana Kalm. in Western Cameroon Using Molecular Markers

Diversity, 2020
Genetic diversity of species is an important baseline for the domestication process. In Cameroon, Prunus africana, an important and threatened medicinal tree, is among the priority species for domestication.
Justine G. Nzweundji, Ulrike Huewe, Nicolas Niemenak, Néhémie T. Donfagsiteli, Klaus Eimert   +4 more
doaj   +1 more source

The dynamics of alternative pathways to compensatory substitution [PDF]

, 2013
The role of epistatic interactions among loci is a central question in evolutionary biology and is increasingly relevant in the genomic age. While the population genetics of compensatory substitution have received considerable attention, most studies ...
Nasrallah, Chris A.
core   +2 more sources

Accurate Allele Frequencies from Ultra-low Coverage Pool-Seq Samples in Evolve-and-Resequence Experiments

G3: Genes, Genomes, Genetics, 2019
Evolve-and-resequence (E+R) experiments leverage next-generation sequencing technology to track the allele frequency dynamics of populations as they evolve.
Susanne Tilk, Alan Bergland, Aaron Goodman, Paul Schmidt, Dmitri Petrov, Sharon Greenblum   +5 more
doaj   +1 more source

Polymorphisms of MicroRNA-146a Gene in Behcet’s Disease in Iraqi Patients

Journal of Pure and Applied Microbiology, 2018
The present study was carried out to detect the association of miR-146a haplotypes polymorphisms with Behcet’s Disease in Iraqi patients, PCR-SSCP technique used in present study, blood was used to DNA extraction, the results show that there was strong
Israa Harjan Mohsen, Mona N. Al-Terehi, Abbas Hussein Mugheer, Ahmed Al-Hachamy, Ali H. Al-Saadi   +4 more
doaj   +1 more source

Haplotypes of [‐794(CATT)5–8/‐173G>C] MIF gene polymorphisms and its soluble levels in cutaneous squamous cell carcinoma in western Mexican population

Molecular Genetics & Genomic Medicine, 2023
Background Some cytokines are strongly implicated in the development of squamous cell carcinoma (SCC) such as the Macrophage migration inhibitory factor (MIF).
Elizabeth Guevara‐Gutiérrez, Marina Ramos‐Súarez, Romina Angélica Villalobos‐Ayala, Alberto Tlacuilo‐Parra, José Francisco Muñoz‐Valle, Victor Tarango‐Martínez, Yeminia Valle, Jorge Ramón Padilla‐Gutiérrez, José Manuel Rojas‐Díaz, Emmanuel Valdés‐Alvarado   +9 more
doaj   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source

Pyrenophora tritici–repentis in Tunisia: Race Structure and Effector Genes

Frontiers in Plant Science, 2019
Tan spot is a destructive foliar wheat disease worldwide and caused by the ascomycete fungus Pyrenophora tritici–repentis (Ptr); it has become more frequent in Tunisia over the last decade.
Sana Kamel, Mejda Cherif, Mohamed Hafez, Therese Despins, Reem Aboukhaddour   +4 more
doaj   +1 more source

SNP-Density Crossover Maps of Polymorphic Transposable Elements and HLA Genes Within MHC Class I Haplotype Blocks and Junction

Frontiers in Genetics, 2021
The genomic region (~4 Mb) of the human major histocompatibility complex (MHC) on chromosome 6p21 is a prime model for the study and understanding of conserved polymorphic sequences (CPSs) and structural diversity of ancestral haplotypes (AHs)/conserved ...
Jerzy K. Kulski, Jerzy K. Kulski, Shingo Suzuki, Takashi Shiina   +3 more
doaj   +1 more source

Optimizing Sequencing Resources in Genotyped Livestock Populations Using Linear Programming

Frontiers in Genetics, 2021
Low-cost genome-wide single-nucleotide polymorphisms (SNPs) are routinely used in animal breeding programs. Compared to SNP arrays, the use of whole-genome sequence data generated by the next-generation sequencing technologies (NGS) has great potential ...
Hao Cheng, Keyu Xu, Jinghui Li, Kuruvilla Joseph Abraham, Kuruvilla Joseph Abraham   +4 more
doaj   +1 more source