Results 91 to 100 of about 330,338 (279)

Haul-out behaviour, site fidelity and vigilance of common seals (Phoca vitulina) and grey seals (Halichoerus grypus) in the tees Estuary [PDF]

, 1994
The project was carried out from the beginning of May to the beginning of July 1994, at Seal Sands, in the Tees estuary. The study aimed to examine (i) ecological and (ii) behavioural aspects of two species of seals, common seals (Phoca vitulina) and ...
Gaspari, Stefania
core  

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Pinniped response to diadromous fish restoration in the Penobscot River Estuary

Frontiers in Conservation Science
Successful conservation of pinnipeds in the northwest Atlantic has led to increasing populations of harbor seals (Phoca vitulina) and gray seals (Halichoerus grypus) in the Gulf of Maine.
Lauri Leach, Lauri Leach, Justin R. Stevens, Kristina Cammen   +3 more
doaj   +1 more source

Pup mortality in a rapidly declining harbour seal (Phoca vitulina) population [PDF]

, 2013
This research was funded by the Scottish Government (www.scotland.gov.uk), Scottish Natural Heritage (www.snh.gov.uk) and the Natural Environment Research Council (www.nerc.ac.uk).
Thompson Dave, Simon Moss (490180), Duck, Callan, Duck, Callan David, Mike Lonergan, Callan Duck (490179), Lonergan Mike, Nora Hanson, Moss Simon, Callan Duck, Dave Thompson, Hanson, Nora Nell, Thompson, David, Mike Lonergan (490181), Dave Thompson (292267), Lonergan, Mike, Hanson Nora, Hanson, Nora, Moss, Simon, Duck Callan, Thompson, Dave, Nora Hanson (490178), Simon Moss   +22 more
core   +2 more sources

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

Whole-genome re-sequencing of the Baikal seal and other phocid seals for a glimpse into their genetic diversity, demographic history, and phylogeny

GigaByte
The Baikal seal (Pusa sibirica) is a freshwater seal endemic to Lake Baikal, where it became landlocked million years ago. It is an abundant species of least concern despite the limited habitat.
Marcel Nebenführ , Ulfur Arnason , Axel Janke   +2 more
doaj   +1 more source

Moravian Church Easter Service at Egg Harbor Cemetery, 1938

, 1938
This image, from 1938, depicts a church service of the Moravian Church of Egg Harbor City, NJ. This service is from Easter Sunday, 1938, and appears to be taken at the Egg Harbor City Cemetery on Moss Mill Road and Hamburg Avenue in Egg Harbor, NJ.

core   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron

Angewandte Chemie, EarlyView.
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej, Arturo Rodríguez‐Banqueri, Danuta Mizgalska, Borys Szmigielski, Zuzanna Nowakowska, Małgorzata Benedyk‐Machaczka, Monika Bzowska, Katarzyna Mikruta, Juan Sebastián Ramírez‐Larrota, Chinanu Agunanne, Olivier Julien, Anthony J. O'Donoghue, Carsten Scavenius, Mario López‐Martín, Enrique Marcos, Łukasz Koziej, Sebastian Glatt, Pablo Guerra, Ulrich Eckhard, Jan Potempa, F. Xavier Gomis‐Rüth   +20 more
wiley   +2 more sources