Results 71 to 80 of about 330,338 (279)

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

open access: yesAdvanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan   +10 more
wiley   +1 more source

In-Water Photo Identification, Site Fidelity, and Seasonal Presence of Harbor Seals (Phoca vitulina richardii) in Burrows Pass, Fidalgo Island, Washington

open access: yesOceans
Little is known about the in-water behavior and site fidelity of harbor seals (Phoca vitulina richardii), as most photo-identification (photo-ID) studies are typically conducted while they are hauled-out on land.
Ciera J. Edison   +2 more
doaj   +1 more source

Discrimination of area differences by the harbor seal [PDF]

open access: yesPsychonomic Science, 1966
An earlier investigation of the underwater size discrimination abilities of the California sea lion (Zalophus californianus) was replicated with Harbor seals (Phoca vitulina). Performance was equivalent even though there was a marked difference in test behavior and general activity level.
Stephen H. Feinstein, Charles E. Rice
openaire   +1 more source

Continuous Evolution System Based on Toxin–Antitoxin System Combined with Base Deaminase Accelerates the In Vivo Modification of Target Proteins

open access: yesAdvanced Science, EarlyView.
The promoted Escherichia coli‐assisted continuous evolution (PEACE) system operates through a stringent three step genetic circuit: target gene mutation via a deaminase–T7 RNA polymerase (T7 RNAP) fusion, coupling variant function to antitoxin expression, and growth based selection of surviving cells.
Xinyu Zhang   +10 more
wiley   +1 more source

Seal from the Egg Harbor City Carnival Parade.

open access: yes, 1915
The seal is from the Egg Harbor City Carnival Parade. The seal is composed of four rings. The outside is white and imprinted, CARNIVAL SEPT., 16-17-18, 1915 "THE IDEAL SPOT FOR YOUR HOME". The rest of the rings are black with white printing.

core   +1 more source

Targeting Hippocampal PTEN Suppresses Ferroptosis and Rescues Cognitive Decline in Alzheimer's Disease via Dual AKT/GSK3β/Nrf2 and AKT/STAT3 Axes

open access: yesAdvanced Science, EarlyView.
PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang   +5 more
wiley   +1 more source

Monitoring Harbor Seal Abundance Counts at Haul-Out Site on Goose Island [PDF]

open access: yes
Phoca vitulina (harbor seal) haul-out behavior provides metabolic benefits, safety, and reproduction opportunities. Collecting seal count data at these sites between different times of day can provide indications about harbor seal abundance as well as ...
Donahue, Galadriel
core  

F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers

open access: yesAdvanced Science, EarlyView.
Near‐atomic cryo‐EM structures of a Gram‐negative F‐type pyocin reveal a conserved tail tip architecture shared with bacteriophage λ together with a previously unrecognized side‐fiber attachment mode. These findings provide new insight into tailocin assembly and host recognition and establish a structural framework for engineering precision ...
Zhiwei Gu   +5 more
wiley   +1 more source

[News Clip: Harbor seal]

open access: yes, 1959
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about a seal receiving medical attention at the Forest Part Zoo in Fort ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

Programmable Topological Magnetic Textures in Above‐Room‐Temperature 2D Ferromagnet Fe3GaTe2

open access: yesAdvanced Science, EarlyView.
This work demonstrates the programmable generation and deterministic modulation of magnetic skyrmion bags with high‐order topological numbers in the above‐room‐temperature 2D ferromagnet Fe3GaTe2 (FGaT) via current‐pulse control. Furthermore, highly efficient electrical manipulation and current‐driven parallel motion of these high‐order topological ...
Hanqing Shi   +8 more
wiley   +1 more source

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