Results 111 to 120 of about 84,533 (300)

Which Samples Should be Learned First: Easy or Hard?

, 2022
An effective weighting scheme for training samples is essential for learning tasks. Numerous weighting schemes have been proposed. Some schemes take the easy-first mode, whereas some others take the hard-first one. Naturally, an interesting yet realistic
Wu, Ou, Zhou, Xiaoling
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

A model of lathe dynamic system when cutting hard-to-work materials

Известия высших учебных заведений. Поволжский регион:Технические науки
Background. Ensuring the surface quality of critical products of aviation equipment, chemical, power engineering, transport systems for various purposes presents certain requirements for the equipment on which surface formation is carried out.
A.A. Ignat'ev, T.G. Nasad, V.A. Dobryakov, V.A. Revyakin   +3 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Solution of Bin Packing Instances in Falkenauer T Class: Not So Hard

Algorithms
In this work, the Bin Packing combinatorial optimization problem is studied from the practical side. The focus is on the Falkenauer T benchmark class, which is a collection of 80 problem instances that are considered hard to handle algorithmically ...
György Dósa, András Éles, Angshuman Robin Goswami, István Szalkai, Zsolt Tuza   +4 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Friction Analysis on Scratch Deformation Modes of Visco-Elastic-Plastic Materials [PDF]

, 2012
Understanding of abrasion resistance and associated surfaces deformation mechanisms is of primary importance in materials engineering and design. Instrumented scratch testing has proven to be a useful tool for characterizing the abrasion resistance of ...
D.J. , Schipper, J. , Jamari, I. , Syafaat, Budi , Setiyana   +3 more
core  

Instability of vibrational modes in hexagonal lattice

, 2017
The phenomenon of modulational instability is investigated for all four delocalized short-wave vibrational modes recently found for the two-dimensional hexagonal lattice with the help of a group-theoretic approach. The polynomial pair potential with hard-
Elena A. Korznikova, Dmitry V. Bachurin, Fomin, S. Y., Dmitriev, S. V., Korznikova, E. A., Sergey Yu. Fomin, Alexander P. Chetverikov, Bachurin, D. V., Chetverikov, A. P., Sergey V. Dmitriev   +9 more
core   +1 more source

Observation of Dynamic Interactions between Fundamental and Second-Harmonic Modes in a High-Power Sub-Terahertz Gyrotron Operating in Regimes of Soft and Hard Self-Excitation

, 2012
Dynamic mode interaction between fundamental and second-harmonic modes has been observed in high-power sub-terahertz gyrotrons [T. Notake et al., Phys. Rev. Lett. 103, 225002 (2009); T. Saito et al. Phys. Plasmas 19, 063106 (2012)].
YAMAGUCHI, YuuSuke, OGAWA, Isamu, OGASAWARA, Shinya, SAITO, Teruo, IKEUCHI, Shinji, YAMADA, Naoki, IKEDA, Ryosuke, TATEMATSU, Yoshinori, IDEHARA, Toshitaka   +8 more
core   +2 more sources