Results 81 to 90 of about 1,076,507 (302)

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

The machinability of nickel-based alloys in high-pressure jet assisted (HPJA) turning

Metalurgija, 2013
Due to their mechanical, thermal and chemical properties, nickel-based alloys are generally included among materials that are hard to machine. An experimental study has been performed to investigate the capabilities of conventional and high-pressure jet ...
D. Kramar, M. Sekulić, Z. Jurković, J. Kopač   +3 more
doaj  

Possibilities of Application of High Pressure Jet Assisted Machining in Hard Turning with Carbide Tools [PDF]

Tribology in Industry, 2017
High Pressure Jet Assisted Machining (HPJAM) in turning is a hybrid machining method in which a high pressure jet of cooling and lubrication fluid, under high pressure (50 MPa), leads to the zone between the cutting tool edge and workpiece.
G. Globočki Lakić, B. Sredanović, D. Kramar, D. Kramar   +3 more
doaj  

Research on surface integrity of AISI M2 workpiece hard-turning precision machining with cubic boron nitride cutting tool [PDF]

Mechanical Sciences
To investigate the surface integrity of AISI M2 workpieces during hard turning with a cubic boron nitride tool, the surface morphology, metamorphic layers, and mechanical properties of 18 hard-turning experimental samples were characterized using ...
T. Zhou, T. Zhou, L. Zhao, T. Chen, T. Chen, J. Liu   +5 more
doaj   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

A Multivariate Statistical Quality Control of AISI 52100 Hardened Steel Turning

IEEE Access, 2020
Hard turning processes have several advantages against traditional turning. Improved surface integrity and short process time are some examples. Surface integrity is one of the most important issues in modeling of machining processes.
George Evangelista, Rogerio Santana Peruchi, Tarcisio Goncalves Brito, Paulo Rotela Junior, Luiz Celio Souza Rocha   +4 more
doaj   +1 more source

Velocity Correlations, Diffusion and Stochasticity in a One-Dimensional System

, 2001
We consider the motion of a test particle in a one-dimensional system of equal-mass point particles. The test particle plays the role of a microscopic "piston" that separates two hard-point gases with different concentrations and arbitrary initial ...
A. Dhar, C. Van den Broeck, Ch. Gruber, D. W. Jepsen, E. Teramoto, H. L. Frisch, I. Bena, J. L. Lebowitz, J. L. Lebowitz, J. Piasecki, M. Aizenman, V. Balakrishnan, V. Balakrishnan   +12 more
core   +1 more source

Constructing a Stochastic Model of Bumblebee Flights from Experimental Data [PDF]

, 2013
PMCID: PMC3592844This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A James, A Mashanova, Aleksei V. Chechkin, AM Edwards, AM Edwards, AM Reynolds, B Lindner, C Hawkes, Christof Markus Aegerter, DW Sims, E Kai, EA Codling, EA Codling, F Bartumeus, F Lenz, F Lenz, F Peruani, Friedrich Lenz, GM Viswanathan, GM Viswanathan, L Giuggioli, M Ragwitz, MC Santos, MJ Plank, NE Humphries, O Bénichou, O Bénichou, O Miramontes, P Bovet, P Dieterich, P Romanczuk, P Romanczuk, PM Kareiva, R Friedrich, Rainer Klages, S Benhamou, S Benhamou, S Petrovskii, TC Ings, TC Ings   +39 more
core   +3 more sources

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel, Charlotte Hennessey, Hannah Lee, Pia Parekh, Sheng‐Han Kuo, Ami Kumar   +5 more
wiley   +1 more source