Results 131 to 140 of about 169,796 (260)
Feasibility of Laminar Plasma-Jet Hardening of Cast Iron Surface
Nontransferred DC laminar plasma jets of stable flow and low impinging pressure acting on the substrate were used to heat W–Mo–Cu cast iron for phase transfer hardening of the surface layer. Substrates were heated in multipass with or without overlapping
潘文霞 +4 more
core +1 more source
Elastoplastic modeling of fatigue cracks
The presented work provides a detailed analysis of modern approaches to creating elastoplastic models of surface crack growth that take into account the influence of the type of biaxial loading on the development of stresses and strains at the crack tip ...
K. A. Vansovich, V. I. Yadrov
doaj +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Fire hardening grant guide. Spanish
Title from PDF cover (viewed on April 11, 2022)."Adaptado de Wildfire Home Retrofit Guide (Guía de Adaptación de Viviendas a los Incendios Forestales), publicación #SP-20-11, con el permiso de la Universidad de Nevada, Extensión de Reno y el Programa ...
core
The working parts of soil cultivation and sowing machines operate under conditions of intense abrasive wear. As wear on the working parts increases, the relative unevenness of their travel depth increases, leading to higher traction resistance and ...
Kanat Uteulov +5 more
doaj +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Contactless gas-phase boriding is suitable for strengthening the surface of precision steel components because it avoids direct contact between the workpiece and the boriding medium, thereby helping to maintain dimensional accuracy and surface roughness.
Shunqi Mei +7 more
doaj +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Work-hardening predicition using a dislocation based model for automotive Interstitial Free (IF) steels [PDF]
With a view to environmental, economic and safety concerns, car manufacturers need to design lighter and safer vehicles in ever shorter development times.
BALAN, Tudor +5 more
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