Results 61 to 70 of about 66,380 (265)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Numerical simulations of progressive hardening by using ABAQUS FEA software
The paper concerns numerical simulations of progressive hardening include phase transformations in solid state of steel. Abaqus FEA software is used for numerical analysis of temperature field and phase transformations.
Domański Tomasz +4 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Physical and mechanical properties of cement stone with superabsorbent polyacrylate solutions
The 3D-technology is becoming widespread in construction. Thus, the development of mixtures with the indifferent set of properties to the influence of the environment is actual.
Evgeniy Korolev +2 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Effect of Cold Stress on Physiological Traits of Pistacia atlantica and P. khinjuk during Acclimation [PDF]
Among the different species of Pistacia genus, P. atlantica is more distributed in cold area than P. khinjuk. In this study, in order to illustrate the physiological mechanisms of cold tolerance under acclimation phenomenon, two experiments were ...
Somayeh Homayoonfar +2 more
doaj
High Power Diode Laser (HPDL) for Fatigue Life Improvement of Steel: Numerical Modelling
This paper deals with the improvement of fatigue life of AISI 1040 steel components by using a High Power Diode Laser (HPDL). First, the meaningfulness of each operational parameter was assessed by varying the experimental laser power and scan speed ...
Stefano Guarino +1 more
doaj +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source

