Results 81 to 90 of about 169,796 (260)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
A new hardening law for strain gradient plasticity
, 2000 A new hardening law of the strain gradient theory is proposed in this paper, which retains the essential structure of the incremental version of conventional J(2) deformation theory and obeys thermodynamic restrictions.
Chen, SH (reprint author), Chinese Acad Sci, Inst Mech, LNM, Beijing 100080, Peoples R China. +2 more
core +1 more source
Investigation of the hardening of cement-based materials with nuclear magnetic resonance (NMR)
, 2022 S.13-33Hydrogen nuclear magnetic resonance (1H NMR) is a direct method to determine the hydrogen content and with it the water content (moisture) in solids.
Dobmann, G., Wolter, B., Pel, L.
core +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Research on the Temperature Field in Laser Hardening
, 2006 Temperature field in the laser hardening process was numerically simulated by MSC.Marc software. The influence of energy density on laser hardening effect is analyzed.
Su YP +5 more
core +1 more source
Numerical simulations of progressive hardening by using ABAQUS FEA software
MATEC Web of Conferences, 2018 The paper concerns numerical simulations of progressive hardening include phase transformations in solid state of steel. Abaqus FEA software is used for numerical analysis of temperature field and phase transformations.
Domański Tomasz +4 more
doaj +1 more source
Morphological Evaluation of Gallesia Integrifolia Seedlings Under Different Water Management Systems
Floresta e Ambiente, 2020 This study aimed to quantify the effects of water management during hardening on seedlings of Gallesia integrifolia (Spreng.) Harms, evaluating leaf temperature, morphometric variables, and their performance after hardening in sandy and clayey soil ...
Paulo Ricardo Lima +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source