Results 91 to 100 of about 367,365 (296)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

UNSTRAIN TEMPERING TECHNOLOGY IN MAGNET SPACE OF THIN-WALLED RING ITEMS

open access: yesAdvanced Engineering Research, 2011
The availability of the external magnetic field for the simultaneous embodiment of hardening reserves and strain elimination of thin-walled ring items at the expense of the magnetic field initiating effect on the martensitic transformation within the ...
Victor N. Pustovoit, Yuri V. Dolgachev
doaj  

Hardening effects on formability limit prediction based on gurson-type damage models and bifurcation analysis [PDF]

open access: yes, 2017
In this work, ductility limits of metallic materials, associated with the occurrence of strain localization, are predicted using the GTN damage model coupled with bifurcation theory.
Abed-Meraim, F., Chalal, H.
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

New nonlinear stress-strain model for loess and its comparative research

open access: yesYantu gongcheng xuebao, 2017
At present, the stress-strain curve of loess can only be described by using different mathematical models according to its morphological type. To achieve a unified description of the stress-strain mathematical model, a new nonlinear model is proposed ...
WANG Li-qin 1, 2, LU Zhong-gang 1, SHAO Sheng-jun 1, 2
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

SOFTENING OF HARDENED MEDIUM-CARBON STEEL DURING HEATING

open access: yesNauka ta progres transportu, 2019
Purpose. The work is aimed to clarify the softening mechanism during the heating of martensite hardened carbon steel, which is of practical importance, especially in the development of the production technology of rolled products with different levels of
I. O. Vakulenko   +3 more
doaj   +1 more source

A priori error estimates for the optimal control of laser surface hardening of steel [PDF]

open access: yes, 2010
A priori error estimates for the optimal control of laser surface hardening of ...
Amiya K   +5 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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