Results 101 to 110 of about 169,796 (260)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Caratterizzazione metallurgica dell acciaio inox 15-5 ph fabbricato con processo di rifusione var ed esr [PDF]
, 2011 The purpose of this thesis is to assess difference between the ESR and VAR remelting systems of 15-5PH steel, and subsequent heat treatments of ageing (precipitation hardening) can influence the microstructure of stainless steel 15-5PH, the mechanical ...
Spaliviero, Alberto
core
New nonlinear stress-strain model for loess and its comparative research
Yantu gongcheng xuebao, 2017 At present, the stress-strain curve of loess can only be described by using different mathematical models according to its morphological type. To achieve a unified description of the stress-strain mathematical model, a new nonlinear model is proposed ...
WANG Li-qin 1, 2, LU Zhong-gang 1, SHAO Sheng-jun 1, 2
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
UNSTRAIN TEMPERING TECHNOLOGY IN MAGNET SPACE OF THIN-WALLED RING ITEMS
Advanced Engineering Research, 2011 The availability of the external magnetic field for the simultaneous embodiment of hardening reserves and strain elimination of thin-walled ring items at the expense of the magnetic field initiating effect on the martensitic transformation within the ...
Victor N. Pustovoit, Yuri V. Dolgachev
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
, 1964 This book intended for shop use tries to familiarize the reader with the peculiari ties of a hardening method which due to its many advantages is now in use,many shops.
Grönegress, Hans Wilh
core +1 more source
Experimental study of tensile response of Strain Hardening UHPFRC at early age [PDF]
, 2017 Strain Hardening Ultra High Performance Fibre Reinforced Concrete (SH-UHPFRC), has a high tensile strength (over 10 MPa) and exhibit significant strain hardening (several ‰) under tensile loads.
Mohamed A. Hafiz +3 more
core +2 more sources