Results 131 to 140 of about 57,819 (310)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A Study of the Relationship between Family Functioning and Psychological Hardiness of High School Students in Isfahan

open access: yesروانشناسی بالینی و شخصیت, 2005
As a buffer personality characteristic against life stress events, the role and significance of psychological hardiness has been shown in several investigations.
Kh. Sharifi, H.R. Arizi, K. Namdari
doaj  

HUBUNGAN ANTARA KEPRIBADIAN HARDINESS DAN STRES KERJA PADA FRESH GRADUATE [PDF]

open access: yes, 2016
Tujuan dari penelitian ini adalah untuk menguji hubungan antara kepribadian hardiness dan stres kerja pada fresh graduate. Sampel dalam penelitian ini adalah 100 pria/wanitafresh graduate yang bekerja di Jakarta berusiaantara 21-24 tahun dengan ...
Rohma, Fildza
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Mindfulness among University Students and Its Relationship to Their Psychological Hardiness

open access: yesEducational Process: International Journal
Background/purpose. This study aimed to examine the mindfulness and psychological hardiness levels among university students and investigate the relationship between mindfulness and psychological hardiness. Materials/Methods.
Ahmad Al Alwan   +2 more
doaj   +1 more source

Hubungan antara Hardiness dengan Self-efficacy pada Lansia Masih Bekerja di Banguntapan Bantul [PDF]

open access: yes, 2015
This research aims to know the relationship between hardiness and self-efficacy of lansia (elderly) who still works in Banguntapan Bantul. The Hypotheses in this research is the relationship between hardiness and self-efficacy of lansia (elderly) who ...
Indriati, F. (Feranita)   +1 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Hardiness Dan Kecenderungan Post Power Syndrome Pada Lanjut Usia Pensiunan Pegawai Negeri Sipil (Pns) Anggota Persatuan Wredatama Republik Indonesia (Pwri) Kecamatan Gajah Mungkur Semarang [PDF]

open access: yes, 2015
Penelitian ini bertujuan untuk mengetahui hubungan antara hardiness dengan kecenderungan post power syndrome. Post power syndrome merupakan sekumpulan gejala mental yang menimbulkan gejala-gejala depresi yang diderita oleh orang yang mengalami stresor ...
Ariyanti, M. (Mahsunah)   +1 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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