Results 141 to 150 of about 57,819 (310)
Bromegrass in Alaska. II. Autumn Food-Reserve Storage, Freeze Tolerance, and Dry-Matter Concentration in Overwintering Tissues as Related to Winter Survival of Latitudinal Ecotypes [PDF]
The objective of this study was to acquire improved understanding of factors that influence winter survival of bromegrass (Bromus spp.) at northern latitudes.
Klebesadel, Leslie J.
core
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Acreage Living, June 2001, Vol.7, no.6 [PDF]
Monthly newsletter for people in Iowa that live on Acreages, produced by Iowa State University Copperative ...
core
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Psychometric Properties of Occupational Hardiness Questionnaire Short form among Nurses
Background & Aim: Occupational hardiness as a set of personality traits is a source of resistance and protection against stressful life events. The aim of this study was assessment of psychometric properties of Occupational Hardiness Scale.
A Akbari Balotanbegan +4 more
doaj
Kobasa Concept of Hardiness [PDF]
The concept of Hardiness was first given by Suzanne C. Kobasa (1979) as a personality style or pattern associated with continued good health and performance under stress.
Mund, P. (Pallabi)
core
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source

