Results 41 to 50 of about 375,626 (299)

The Influence of Wheel/Rail Contact Conditions on the Microstructure and Hardness of Railway Wheels [PDF]

open access: yes, 2014
The susceptibility of railway wheels to wear and rolling contact fatigue damage is influenced by the properties of the wheel material (microstructure and hardness).
Bevan, Adam   +7 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Steiner tree problem on graphs: inapproximability results [PDF]

open access: yes, 2008
The Steiner tree problem on weighted graphs seeks a minimum weight subtree containing a given subset of the vertices (terminals). We show that it is NP-hard to approximate the Steiner tree problem within a factor 96/95.
Chlebikova, Janka   +3 more
core   +1 more source

Virtual Sensor for On-Line Hardness Assessment in TIG Welding of Inconel 600 Alloy Thin Plates

open access: yesSensors
Maintaining high-quality welded connections is crucial in many industries. One of the challenges is assessing the mechanical properties of a joint during its production phase.
Jacek Górka   +4 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

A contact area function for Berkovich nanoindentation : Application to hardness determination of a TiHfCN thin film [PDF]

open access: yes, 2014
In nanoindentation, especially at very low indenter displacements, the indenter/material contact area must be defined in the best possible way in order to accurately determine the mechanical properties of the material.
LOUIS, G.   +12 more
core   +1 more source

Enhancement in the Hardness and Corrosion Resistance of Mild Steel Surfaces by Nickel-Chromium Addition and Rapid Cooling After Welding

open access: yesJournal of Applied Science and Engineering
In a corrosive environment, it is crucial to increase the hardness and corrosion resistance of mild steel bucket excavators. Making a hard layer of nickel-chromium (NiCr) alloy by the deposition method is one of the many approaches to achieve this.
Sopiyan   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pancake Flipping Is Hard [PDF]

open access: yesJournal of Computer and System Sciences, 2012
Corrected ...
Laurent Bulteau   +2 more
openaire   +9 more sources

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