Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
Effect of the over-ageing treatment on the mechanical properties of AA2024 aluminum alloy. [PDF]
The evolution of the hardness of the over-ageing AA2024 alloy scale was followed by measurements of Vickers hardness. The nanoindentation is adapted to the determination of elastoplastic properties (hardness and Young’s modulus) of the matrix and also of
Abrudeanu, Marioara+6 more
core
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Study of hot hardness characteristics of tool steels [PDF]
Hardness measurements of tool steel materials in electric furnace at elevated temperatures and low oxygen environment are discussed. Development of equation to predict short term hardness as function of intial room temperature hardness of steel is ...
Chevalier, J. L.+2 more
core +1 more source
Mechanical Properties of Scots pine (Pinus sylvestris) with Impregnation Modifiers [PDF]
Wood modification is a promising alternative to improving the performance of wood without harmful side effects. This study investigates impregnation modification and its effects on the mechanical properties of solid wood, which has been paid limited ...
Ville LAHTELA, Timo KARKI
doaj
Mechanical Properties and Microstructure of WE43 Mg Alloy Processed by Warm ECAPFollowed by Extrusion [PDF]
In the present paper, the effects of the subsequent extrusion after multi-pass equal-channel angular pressing (ECAP) process on the mechanical properties and microstructure of WE43 magnesium alloy are investigated.
A. Torkian, G. Faraji, M. Karimpour
doaj +1 more source
The Hardness of Additively Manufactured Alloys
The rapidly evolving field of additive manufacturing requires a periodic assessment of the progress made in understanding the properties of metallic components. Although extensive research has been undertaken by many investigators, the data on properties
T. DebRoy, J. Zuback
semanticscholar +1 more source
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi+2 more
wiley +1 more source
On the Hardness of a New Boron Phase, Orthorhombic {\gamma}-B28
Measurements of the hardness of a new high-pressure boron phase, orthorhombic {\gamma}-B28, are reported. According to the data obtained, {\gamma}-B28 has the highest hardness (~50 GPa) of all known crystalline modifications of ...
A. R. Oganov+10 more
core +1 more source
Hardness of Demineralized Enamel with the Application of Toothpaste Containing Green Tea Extract [PDF]
The aim of this study was to analyze the influence of toothpastes with or without green tea extract on the enamel hardness. Human teeth were used as specimens and surface enamel demineralization by soaking in 1% citric acid.
Indrani, D. J. (Decky)+2 more
core +2 more sources