Results 61 to 70 of about 505,352 (366)

Design of Wear-Resistant Diecast AlSi9Cu3(Fe) Alloys for High-Temperature Components

open access: yesMetals, 2019
Type AlSi9Cu3(Fe) alloy has been modified by alloying with iron, manganese, and chromium elements to develop wear-resistant diecast hypoeutectic Al−Si−Cu alloys that can be applied for high-temperature applications.
Giulio Timelli   +3 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

The Relationship of Hard X-ray and Optical Line Emission in Low Redshift Active Galactic Nuclei [PDF]

open access: yesAstrophys.J.634:161-168,2005, 2005
In this paper we assess the relationship of the population of Active Galactic Nuclei (AGN) selected by hard X-rays to the traditional population of AGN with strong optical emission lines. First, we study the emission-line properties of a new hard X-ray selected sample of 47 local AGN (classified optically as both Type 1 and Type 2 AGN).
arxiv   +1 more source

Sintering studies on iron-carbon-copper compacts [PDF]

open access: yesScience of Sintering, 2016
Sintered Iron-Carbon-Copper parts are among the most widely used powder metallurgy product in automobile. In this paper, studies have been carried out to find out the sintering characteristics of iron-carbon-copper compacts when sintered in ...
Perianayagam Philomen-D-Anand Raj   +2 more
doaj   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

How hard are hard triggers? [PDF]

open access: yes, 2012
International ...
Jayez, Jacques, Mongelli, Valeria
openaire   +2 more sources

Effect of Severe Plastic Deformation on the Conductivity and Strength of Copper-Clad Aluminium Conductors

open access: yesMetals, 2019
Aluminium rods with different copper sheath thicknesses were processed by severe plastic deformation at room temperature and then annealed, to join the constituent metals and produce a nanocrystalline microstructure.
Rimma Lapovok   +3 more
doaj   +1 more source

Effect of soya milk on nutritive, antioxidative, reological and textural properties of chocolate produced in a ball mill [PDF]

open access: yesHemijska Industrija, 2011
Chocolate is a complex rheological system in which non-fat cocoa particles and sugar particles are enveloped by crystal matrix of cocoa butter. Physical properties of chocolate depend on ingredient composition, method of production and properly ...
Zarić Danica B.   +5 more
doaj   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

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