Results 51 to 60 of about 4,746,761 (313)

Prevention and Harm Reduction Interventions for Adult Gambling at the Local Level: An Umbrella Review of Empirical Evidence

International Journal of Environmental Research and Public Health, 2021
Concerns about negative consequences of gambling diffusion are increasing. Prevention and harm reduction strategies play a crucial role in reducing gambling supply and harms.
V. Velasco, P. Scattola, Laura Gavazzeni, Lara Marchesi, Ioana Elena Nita, Gilberto Giudici   +5 more
semanticscholar   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Organizational support for frontline harm reduction and systems navigation work among workers with living and lived experience: qualitative findings from British Columbia, Canada

Harm Reduction Journal, 2021
Background The inclusion of people with lived and living experience of substance use is essential to effective and client-centered harm reduction services and strategies.
A. Greer, J. Buxton, B. Pauly, V. Bungay
semanticscholar   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Professional education to reduce provider stigma toward harm reduction and pharmacotherapy

Drugs: Education, Prevention and Policy, 2021
Aims A novel professional training was developed to reduce stigma toward harm reduction and pharmacotherapy for substance use disorders. Methods The training was delivered over three sessions to n = 147 health professionals in Utah between 2019 and 2020,
Sandra H. Sulzer, Suzanne Prevedel, T. Barrett, M. Voss, Cassandra Manning, E. Madden   +5 more
semanticscholar   +1 more source

Homelessness and harm reduction [PDF]

Canadian Medical Association Journal, 2006
Every night, about 800 000 Americans and tens of thousands of Canadians sleep on the street or in homeless shelters.[1][1],[2][2] Countless more stay temporarily with friends or relatives because they have no home of their own.[3][3] Those who experience homelessness represent a remarkably ...
openaire   +3 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Women and barriers to harm reduction services: a literature review and initial findings from a qualitative study in Barcelona, Spain

Harm Reduction Journal, 2020
Background There are an estimated 3.2 million women who inject drugs worldwide, constituting 20% of all people who inject drugs. The limited data that are available suggest that women who inject drugs are at greater risk of HIV and viral hepatitis ...
Sam Shirley-Beavan, A. Roig, N. Burke-Shyne, Colleen Daniels, Róbert Csák   +4 more
semanticscholar   +1 more source

Lisbon’s COVID 19 response: harm reduction interventions for people who use alcohol and other drugs in emergency shelters

Harm Reduction Journal, 2021
Four emergency shelters were instituted in Lisbon during COVID-19, and are still in operation. Between March and August 2020, they served over 600 people.
R. Fuertes, Elsa Belo, Cristiana S Merendeiro, A. Curado, D. Gautier, A. Neto, H. Taylor   +6 more
semanticscholar   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source