Results 71 to 80 of about 225,166 (306)

Values and preferences for hepatitis C self-testing among people who inject drugs in Kyrgyzstan

BMC Infectious Diseases, 2021
Background The prevalence of hepatitis C virus (HCV) among people who inject drugs (PWID) continues to be a major public-health burden in this highly stigmatised population. To halt transmission of HCV, rapid HCV self-testing kits represent an innovative
Guillermo Z. Martínez-Pérez, Danil S. Nikitin, Alla Bessonova, Emmanuel Fajardo, Sergei Bessonov, Sonjelle Shilton   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

C no more: a prospective single-arm study to evaluate the effectiveness of a nurse and peer-led mobile model of hepatitis C testing and treatment at community corrections offices

Health & Justice
Background The community corrections population in Australia shares similar risk factors for hepatitis C virus (HCV) infection with people incarcerated in prisons, but without access to prison-based testing and treatment.
Samara Griffin, Timothy Papaluca, Jacinta A Holmes, Bridget Reid, Anne Craigie, Jane Dicka, Sione Crawford, Amanda Callus, Mark Belzer, Tim Spelman, Margaret Hellard, Shelley Walker, Mark Stoové, Alexander J Thompson, Rebecca J Winter   +14 more
doaj   +1 more source

Smoking Harm Reduction

American Journal of Public Health, 2016
A letter to the editor is presented in response to the article "New product marketing blurs the line between nicotine replacement therapy and smokeless tobacco products," by Ganna Kostygina, Lucinda England and Pamela M. Ling along with a response from the authors.
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The global state of harm reduction 2010: key issues for broadening the response. [PDF]

, 2010
This report provides a region-by-region update of key developments in harm reduction since the first Global State report was released in 2008. It also explores several issues key to the response to drug-related harms worldwide, including increasing ...

core  

Harm Reduction

Radical History Review
Harm reduction and risk reduction: practices at the intersection of queer, addiction and antiracist activism, which refuses to ask the question of use and dependence from the point of view of eradication, and instead embarks on the definitively impure paths of mutual aid. A pleasure activism and everyday life willfulness, a poem for survival.
J. David Stiffler, Ariane Ling, Gentry Torell, Victoria Jonas   +3 more
  +7 more sources

‘This is PEEP’ participatory qualitative study: learning from a provincial consultation and advisory group of people with lived and living experience of substance use in British Columbia, Canada

BMJ Open
Objectives To summarise PEEP’s (Professionals for Ethical Engagement of Peers—a group of consultants with lived and living experience of substance use) outputs and gain insights into PEEP’s impact and suggestions for the future.Design Included an ...
Jane A Buxton, Kurt Lock, Charlene Burmeister, Kerolos Daowd, Jessica Lamb, Jenny McDougall, Amirnima Danaei, Paul Choisil, Elizabeth Haywood, Iesha Henderson, Kali Sedgemore   +10 more
doaj   +1 more source

Participant perceptions on the acceptability and feasibility of a telemedicine-based HIV PrEP and buprenorphine/naloxone program embedded within syringe services programs: a qualitative descriptive evaluation

Harm Reduction Journal, 2022
Background People who inject drugs (PWID) are at risk for HIV and opioid overdose. We piloted PARTNER UP, a telemedicine-based program to provide PWID with access to both oral pre-exposure prophylaxis (PrEP) for HIV prevention and medication for opioid ...
Amy Corneli, Brian Perry, Andrea Des Marais, Yujung Choi, Hillary Chen, Rebecca Lilly, Denae Ayers, Jesse Bennett, Lauren Kestner, Christina S. Meade, Nidhi Sachdeva, Mehri S. McKellar   +11 more
doaj   +1 more source