Results 81 to 90 of about 3,578,042 (213)

Reducing structural harm to empower youth [PDF]

open access: yes, 2019
Presented at the Harm Reduction International Conference (HR19), Porto, Portugal 2019. Amidst one of the most significant public health emergencies, Vancouver Coastal Health (VCH) recognized the need to address the growing and changing needs of youth ...

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Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

How understanding and application of drug-related legal instruments affects harm reduction interventions in Cambodia: a qualitative study

open access: yes, 2017
Background Harm reduction interventions in Cambodia face numerous obstacles because of conflicting understanding and interests and inconsistencies in the implementation by law enforcement officials.
Tola Chan   +35 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Good Practices and Ethical Data Collection at Harm Reduction Programs: A Brief Summary

open access: yes, 2023
This guidance is for harm reduction programs and for funders and others who require data from programs. This is a brief summary of good and ethical data collection and data use practices in harm reduction programs. The guidance may help programs evaluate
Buer, Lesly-Marie
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Hotel of Last Resort: Enhancing User Agency in Harm Reduction Architecture

open access: yes, 2020
Homeless individuals who use drugs represent some of the most vulnerable and marginalized among society. In the context of a national opioid epidemic in Canada, harm reduction strategies, which reduce the adverse consequences associated with practices or
Manoy, Kamille
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Harm Reduction and Person-Centered Language

open access: yes, 2021
Summarize the history and principles of harm reduction. Identify examples of harm reduction and explain the importance of harm reduction.
Sweet, Liz   +2 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

People who use drugs and mental health. [PDF]

open access: yes, 2021
Ongoing discussions, including among key international donors, have raised concerns within Harm Reduction International and the International Network of People who Use Drugs (INPUD) about the proposed inclusion of mental health within the harm reduction ...

core  

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