Results 31 to 40 of about 4,384,582 (248)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Agricultura, 2018 The veterinarian from the emergency service is part of the professional group exposed to biological agents harmful to the health. The main types of biological agent can be zoonotic and vector born diseases.
Cosmin Peștean +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Harmful biological agents in preschools [PDF]
, 2014 Głównym zagrożeniem zawodowym dla wychowawców nauczania przedszkolnego jest kontakt z wydzielinami i wydalinami organizmów dzieci oraz bioaerozolem emitowanym przez nie w trakcie zabawy.
Gołofit-Szymczak, M. +2 more
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Journal of Biological Regulators and Homeostatic Agents
, 2006 Journal of Biological Regulators & Homeostatic Agents is published every three months. The journal publishes original papers describing research in the fields of experimental and clinical medicine, molecular biology, biochemistry, regulatory molecules ...
BOLOGNESI, ANDREA
core +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
A healthier way to control harmful agents: biological control
Revista MENDIVE, 2008 This article is based on the assessment of the biological struggle, as an essential element in the Entire Management of Plagues, in order to reduce de negative impact that the irrational use of chemical products produces on nature, and in order to ...
Célida León Hernández +2 more
doaj
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Harmful biological agents in dental care facilities [PDF]
, 2012 Głównym zagrożeniem zawodowym dla personelu medycznego w gabinetach stomatologicznych jest kontakt z krwią i śliną pacjenta oraz bioaerozol powstający podczas pracy z wysokoobrotowymi narzędziami stomatologicznymi.
Ławniczek-Wałczyk, A. +3 more
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