Results 31 to 40 of about 90,732 (260)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Chemically and Biologically Harmless versus Harmful Ferritin/Copper–Metallothionein Couples [PDF]
Chemistry – A European Journal, 2014 AbstractThe simultaneous measurement of the decrease of available FeII ions and the increase of available FeIII ions allowed the analysis of the ferroxidase activity of two distinct apoferritins. Although recombinant human apoferritin (HuFtH) rapidly oxidizes FeII to FeIII, this iron is not properly stored in the ferritin cavity, as otherwise occurs in
Fernando Carmona +7 more
openaire +3 more sources
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
An experimental study of messages communicating potential harms of electronic cigarettes.
PLoS ONE, 2020 There has been an upsurge of e-cigarette use in the United States in recent years. While e-cigarettes may contain lower levels of toxic chemicals than combusted cigarettes, they still pose serious health hazards, including increased risk for heart and ...
Daniel Owusu +2 more
doaj +1 more source
The Invisible Barrier to Safe Textile Recycling
Frontiers in Sustainability, 2022 • Presence of certain chemical additives (e.g. halogenated flame retardants, perfluoroalkyl substances, and phthalates) could hinder textile recycling operations as their presence renders end-of-life materials as “hazardous” and therefore not recyclable;•
Martin Sharkey, Marie Coggins
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Farklı Lokasyonlardan Alınan İçme Sularında Ağır Metal Analizi
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2014 Dünyada endüstri ve şehirleşmenin artmasıyla giderek artan bir su ihtiyacı oluşmaktadır. Ağır metaller de içme suyu ile insan vücuduna alınan kimyasallar arasındadır. Yüksek seviyede ağır metal maruziyetinde ise insan vücuduna olumsuz etkileri vardır. Bu
Bayram Poyraz
doaj
Case Studies in Chemical and Environmental EngineeringIn this study, the environmental concepts were applied to preserve the environment by utilizing natural materials instead of harmful chemicals to synthesize a nanocomposite comprising quartz sand reinforced with Fe/Zn nanoparticles, wherein eucalyptus ...
Haneen Salih Hadi, Ziad Tark Abd Ali
doaj +1 more source