Results 1 to 10 of about 270,239 (265)

In Vivo Rapid Assessment of Compound Exposure (RACE) for Profiling the Pharmacokinetics of Novel Chemical Probes [PDF]

Current Protocols in Chemical Biology, 2012
AbstractThe Rapid Assessment of Compound Exposure (RACE) assay is an easy and efficient method for estimating the pharmacokinetic parameter of exposure (AUC: area under the curve) of novel chemical probe compounds in mice. RACE is a truncated and compressed version of a traditional comprehensive in vivo pharmacokinetics study.
Danielle, McAnally, Michael, Vicchiarelli, Khandaker, Siddiquee, Layton H, Smith   +3 more
exaly   +3 more sources

In-situ Real-Time Monitoring of Volatile Organic Compound Exposure and Heart Rate Variability for Patients with Multiple Chemical Sensitivity [PDF]

International Journal of Environmental Research and Public Health, 2015
In-situ real-time monitoring of volatile organic compound (VOC) exposure and heart rate variability (HRV) were conducted for eight multiple chemical sensitivity (MCS) patients using a VOC monitor, a Holter monitor, and a time-activity questionnaire for 24 h to identify the relationship between VOC exposure, biological effects, and subjective symptoms ...
Hiroaki Kumano, Kazukiyo Kumagai, Atsushi Mizukoshi   +2 more
exaly   +3 more sources

Exposure to an accidental trichlorosilane spill: three case reports [PDF]

Clinical and Experimental Emergency Medicine, 2022
Chlorosilane is a hazardous chemical compound which is used as a raw material in the production of silicone. Despite strict restrictions, accidental spillage of chlorosilane is often reported.
Chang Won Park, Seong Hun Kim, Soo Hyung Lee, Shinwoo Kim, Woo Young Nho   +4 more
doaj   +1 more source

Sociodemographic and clinical profile of patients with occupational contact dermatitis seen at a work-related dermatology service, 2000 - 2014 [PDF]

Anais Brasileiros de Dermatologia, 2019
: BACKGROUND: Occupational dermatoses are common, especially contact dermatitis. Epidemiological studies on these dermatoses are scarce in Brazil and they are necessary as part of the public policy to protect workers' health.
Maria das Graças Mota Melo, Ana Luiza Castro Fernandes Villarinho, Iuri da Costa Leite   +2 more
doaj   +1 more source

Impact of Chemicals on the Age of Menarche: A Literature Review

Children, 2023
A growing body of evidence suggests that chemicals interfere with the age of onset of menarche. We conducted a review in order to demonstrate the relationship between several categories of chemicals and menarche.
Xristos Anastasiadis, Alkis Matsas, Theodoros Panoskaltsis, Panagiotis Bakas, Dimitrios T. Papadimitriou, Panagiotis Christopoulos   +5 more
doaj   +1 more source

Review on cumulative exposure risk assessment model and method of combined action of chemical mixtures at home and abroad

Zhongguo shipin weisheng zazhi, 2022
The combined effects of human exposure to chemical mixtures have attracted the attention of government agencies in many countries. Many institutions have carried out a lot of research on the cumulative exposure assessment of the combined effects of ...
BAO Hanbing, LIU Zhaoping, WEI Sheng, SONG Yan   +3 more
doaj   +1 more source

Innovative therapeutic approach to chemical burns produced by vesicants; an experimental study

Journal of Mind and Medical Sciences, 2022
Vesicants are compounds that cause severe toxic effects on various tissues. Such chemical action causes tissue necrosis, with clinical expression of skin lesions with a burning character and characteristic blisters.
Cristina Anca Secară, Otilia Liudmila Cinteză, Diana Popescu, Claudia Valentina Popa, Camelia Andreea Hîrjeu, Oana Cristina Voinea, Luiza Georgia Șerbănescu, Andreea Marilena Păuna, Mihail Silviu Tudosie   +8 more
doaj   +1 more source

Chemical-by-chemical and cumulative risk assessment of residential indoor exposure to semivolatile organic compounds in France [PDF]

Environment International, 2018
The toxic effects of environmental exposure to chemicals are increasingly being studied and confirmed, notably for semivolatile organic compounds (SVOCs). These are found in many products and housing materials, from which they are emitted to indoor air, settled dust and other surfaces.The objective of this work is to assess the human health risk posed ...
Pelletier, Maud, Glorennec, Philippe, Mandin, Corinne, Le Bot, Barbara, Ramalho, Olivier, Mercier, Fabien, Bonvallot, Nathalie   +6 more
openaire   +2 more sources

Open, High-Resolution EI+ Spectral Library of Anthropogenic Compounds

Frontiers in Public Health, 2021
To address the lack of high-resolution electron ionisation mass spectral libraries (HR-[EI+]-MS) for environmental chemicals, a retention-indexed HR-[EI+]-MS library has been constructed following analysis of authentic compounds via GC-Orbitrap MS.
Elliott J. Price, Elliott J. Price, Jirí Palát, Katerina Coufaliková, Petr Kukučka, Garry Codling, Chiara Maria Vitale, Štěpán Koudelka, Jana Klánová   +8 more
doaj   +1 more source

Azole selenourea disrupted the midgut and caused malformed development of Plutella xylostella

Journal of Integrative Agriculture, 2023
Chemical insecticides targeting the digestive system of diamondback moth (DBM), Plutella xylostella, have not been developed. The discovery of an insecticide with novel mode of action is a challenge for the control of DBM.
Xue-ying GUO, Zi-hao HUANG, Lan-tu XIONG, Li DONG, Yue-kun HUANG, Lin-hao WEI, Ri-yuan TANG, Zhi-lin WANG, Han-hong XU   +8 more
doaj   +1 more source